Gary D. Kao

faculty photo
Associate Professor of Radiation Oncology
Attending Staff Physician, Department of Radiation Oncology, Hospital of the University of Pennsylvania
Attending Staff Physician, Philadelphia Veterans Medical Center, Department of Radiation Oncology
Consulting Staff, Chester County Hospital
Staff Physician, Pennsylvania Hospital, Department of Radiation Oncology
Consulting Staff, Presbyterian Hospital
Consulting Staff, Capital Health Systems at Mercer
Associate Medical Staff, Holy Redeemer Hospital, Department of Radiation Oncology
Chief, Brachytherapy Services, Philadelphia Veterans Medical Center, Department of Radiation Oncology
Department: Radiation Oncology

Contact information
Department of Radiation Oncology
Smilow Center for Translational Research, Room 8-134
3400 Civic Center Blvd.
University of Pennsylvania
Philadelphia, PA 19104
Office: 215-573-2285
Graduate Group Affiliations
Education:
BA (Philosophy)
Johns Hopkins University , 1984.
M.D. (Medicine)
Johns Hopkins School of Medicine, 1988.
PhD (Molecular Biology)
University of Pennsylvania, 1998.
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Description of Research Expertise

Molecular and Cellular Biology

Description of Itmat Expertise

The Kao laboratory studies mechanisms governing cancer cell viability and treatment resistance, with a primary focus on mechanisms mediated by histone deacetylase and mitotic checkpoint regulation. We have also helped pioneer the use of zebrafish as novel vertebrate model system for translational research.

Selected Publications

Ju M, Kao GD, Steinmetz D, Chandrasekaran S, Keefe SM, Guzzo TJ, Christodouleas JP, Hahn SM, Dorsey JF.: Application of a telomerase-based circulating tumor cell (CTC) assay in bladder cancer patients receiving postoperative radiation therapy: A case study. Cancer Biol Ther. 15(6): 683-7, Jun 2014.

Macarthur KM, Kao GD, Chandrasekaran S, Alonso-Basanta M, Chapman C, Lustig RA, Wileyto EP, Hahn SM, Dorsey JF.: Detection of brain tumor cells in the peripheral blood by a telomerase promoter-based assay. Cancer Res. 74(8): 2152-9, Apr 2014.

MacArthur KM, Kao GD, Hahn SM, Christodouleas JP, Bekelman JE, Dorsey JF: Preliminary results of a telomerase-based circulating tumor cell assay in prostate cancer patients undergoing definitive radiotherapy. J Clin Oncol. 32(4), Feb 2014.

Al Zaki A, Joh D, Cheng Z, de Barros AL, Kao G, Dorsey J, Tsourkas A.: Gold-Loaded Polymeric Micelles for Computed Tomography-Guided Radiation Therapy Treatment and Radiosensitization. ACS nano 8(1): 104-12, Jan 2014.

Joh DY, Kao GD, Murty S, Stangl M, Sun L, Al Zaki A, Xu X, Hahn SM, Tsourkas A, Dorsey JF.: Theranostic gold nanoparticles modified for durable systemic circulation effectively and safely enhance the radiation therapy of human sarcoma cells and tumors. Transl Oncol. 6(6): 722-31, Dec 2013.

Joh DY, Sun L, Stangl M, Al Zaki A, Murty S, Santoiemma PP, Davis JJ, Baumann BC, Alonso-Basanta M, Bhang D, Kao GD, Tsourkas A, Dorsey JF. : Selective targeting of brain tumors with gold nanoparticle-induced radiosensitization. PLoS One. 8(4), Apr 30 2013.

Chandrasekaran S, Hollander A, Xu X, Benci JL, Davis JJ, Dorsey JF, Kao G.: 18F-fluorothymidine-pet imaging of glioblastoma multiforme: effects of radiation therapy on radiotracer uptake and molecular biomarker patterns. ScientificWorldJournal. 2013, Apr 4 2013.

Kimple RJ, Kao GD: A 10-year analysis of american society for radiation oncology junior faculty career development awards. Int J Radiat Oncol Biol Phys. 85(4): 924-8, Mar 2013.

Baumann BC, Kao GD, Mahmud A, Harada T, Swift J, Chapman C, Xu X, Discher DE, Dorsey JF: Enhancing the Efficacy of Drug-loaded Nanocarriers against Brain Tumors by Targeted Radiation Therapy. Oncotarget. 4(1): 64-79, Jan 2013.

Baumann BC, Dorsey JF, Benci JL, Joh DY, Kao GD: Stereotactic intracranial implantation and in vivo bioluminescent imaging of tumor xenografts in a mouse model system of glioblastoma multiforme. J Vis Exp.(67), Sep 25 2012.

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Last updated: 06/13/2014
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