Jae W. Song
Assistant Professor of Radiology at the Hospital of the University of Pennsylvania
Active, Pennsylvania Hospital – Department of Radiology, Division of Neuroradiology
Active, Chester County Hospital – Department of Radiology Neuroradiology
Active, Penn Presbyterian Medical Center – Department of Radiology, Division of Neuroradiology
Attending, Hospital of the University of Pennsylvania – Department of Radiology, Division of Neuroradiology
Department: Radiology
Contact information
University of Pennsylvania
Perelman School of Medicine
Department of Radiology
3400 Spruce St., 1 Silverstein, Ste. 130
Philadelphia, PA 19104
Perelman School of Medicine
Department of Radiology
3400 Spruce St., 1 Silverstein, Ste. 130
Philadelphia, PA 19104
Publications
Education:
BA (Biology, Magna Cum Laude)
University of Pennsylvania, 2000.
MD (Medicine, Honors in Cell Biology)
New York University School of Medicine, 2008.
MS (Biostatistics and Clinical Epidemiology)
University of Michigan, School of Public Health, 2010.
BA (Biology, Magna Cum Laude)
University of Pennsylvania, 2000.
MD (Medicine, Honors in Cell Biology)
New York University School of Medicine, 2008.
MS (Biostatistics and Clinical Epidemiology)
University of Michigan, School of Public Health, 2010.
Post-Graduate Training
Fulbright Scholar (Developmental Biology), University of Freiburg, 2001-2002.
Max Kade Fellow, Department of Surgery, Medical University of Vienna, Austria, 2007-2007.
Internship, General Surgery, University of Michigan Hospital Systems, 2008-2009.
Research Fellow, Hand Surgery, University of Michigan Medical School, 2009-2011.
Research Fellow, Newborn Medicine, Boston Children’s Hospital, 2011-2012.
Residency, Diagnostic Radiology, Hahnemann University Hospital, 2012-2013.
Residency, Diagnostic Radiology and Biomedical Imaging, Yale New Haven Hospital, 2013-2016.
Andlinger Fellow, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Austria, 2015-2015.
Clinical Fellow, Diagnostic Radiology, Division of Neuroradiology, Massachusetts General Hospital, 2016-2017.
Chief Fellow, Diagnostic Radiology, Division of Neuroradiology, Massachusetts General Hospital, 2017-2018.
Permanent linkFulbright Scholar (Developmental Biology), University of Freiburg, 2001-2002.
Max Kade Fellow, Department of Surgery, Medical University of Vienna, Austria, 2007-2007.
Internship, General Surgery, University of Michigan Hospital Systems, 2008-2009.
Research Fellow, Hand Surgery, University of Michigan Medical School, 2009-2011.
Research Fellow, Newborn Medicine, Boston Children’s Hospital, 2011-2012.
Residency, Diagnostic Radiology, Hahnemann University Hospital, 2012-2013.
Residency, Diagnostic Radiology and Biomedical Imaging, Yale New Haven Hospital, 2013-2016.
Andlinger Fellow, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Austria, 2015-2015.
Clinical Fellow, Diagnostic Radiology, Division of Neuroradiology, Massachusetts General Hospital, 2016-2017.
Chief Fellow, Diagnostic Radiology, Division of Neuroradiology, Massachusetts General Hospital, 2017-2018.
Description of Itmat Expertise
NeuroradiologyStroke/Transient Ischemic Attack
Atherosclerosis
CNS Vasculitis
Description of Research Expertise
Dr. Song’s research seeks to understand one of the most clinically impactful questions in cerebrovascular disease: what is the stroke mechanism? To this end, her work centers on establishing imaging biomarkers of atherosclerosis and inflammatory vasculitis using advanced non-invasive MR and CT imaging techniques to guide therapy and monitor treatment. She images the intracranial and extracranial vasculature in submillimeter resolution to draw mechanistic insight about the development and progression of disease in the vessel walls. Her research in vessel wall imaging complements the multidisciplinary expertise of the Penn Comprehensive Stroke Center. Together, the teams are committed to translating innovative diagnostic imaging technologies to provide patients with integrated and personalized care. She completed a master's degree in clinical research with a focus on study design, biostatistics and epidemiology at the University of Michigan School of Public Health. She serves on committees for the American Stroke Association, American Society of Neuroradiology, American Society of Functional Neuroradiology, Radiological Society of North America (RSNA) and International Society of Magnetic Resonance in Medicine and reviews grants for the RSNA, Netherlands Organisation for Scientific Research, Deutsche Forschungsgemeinshaft, and Austrian Science Fund. She is an Associate Editor for Radiology Advances. Her national and international awards include a Fulbright Fellowship to Freiburg, Germany, NIH NRSA Award, recognition for Research Excellence by the American Heart Association, and Andlinger Fellowship at the Medical University of Vienna, Austria.Selected Publications
Saba L, Cau R, Murgia1 A, Nicolaides AN, Wintermark M, Castillo M, Staub D, Kakkos S, Yang Q, Paraskevas KI, Yuan C, Edjlali1 M, Sanfilippo R, Hendrikse J, Johansson E, Mossa-Basha M, Balu N, Dichgans M, Saloner D, Bos D, Jager RH, Naylor R, Faa G, Suri JS, Costello J, Auer DP, McNally S, Bonati LH, Nardi V, van der Lugt A, Griffin M, Wasserman BA, Kooi ME, Gillard J, Lanzino G, Mikhailidis DP, Mandell DM, Benson J, van Dam-Nolen D, Kopczak A, Song JW, Gupta A, Demarco JK, Chaturvedi S, Virmani R, Hatsukami T, Brown M, Moody AR, Libby P, Schindler A*, Saam T*. : Carotid Plaque-RADS Classification, A Novel Stroke Risk Classification System. Journal of the American College of Cardiology Sept 2023 Notes: *Equal contribution.Song JW#, Frame MY, Sellers RT, Klahn C, Fitzgerald K, Pomponio B, Schnall MD, Kasner SE, Loevner, LA.: Implementation of a Clinical Vessel Wall MR Imaging Program at an Academic Medical Center. American Journal of Neuroradiology Mar 2024 Notes: (#Corresponding author.).
Song JW*, Xiao J*, Cen SY, Liu X, Wu F, Schlick K, Li D, Yang Q, Song SS, Fan Z: Sex-Differences in Intracranial Atherosclerosis in Hypertensive Patients with Acute Ischemic Stroke. Journal of the American Heart Association Page: e025579, May 2022 Notes: *Equal contribution.
Guggenberger KV*, Pavlou A*, Cao Q, Bhatt IJ, Cui QN, Bley TA, Curtin HD, Savatovsky J, Song JW#: Orbital Magnetic Resonance Imaging of Giant Cell Arteritis with Ocular Manifestations: A Systematic Review and Individual Participant Data Meta-Analysis. European Radiology May 2023 Notes: (*Equal Contribution. #Corresponding Author) DOI: 10.1007/s00330-023-09770-2.
Sakai Y, Lehman VT, Eisenmenger LB, Obusez EC, Kharal GA, Xiao J, Wang GJ, Fan Z, Cucchiara BL, Song JW#: Vessel Wall MR Imaging of Aortic Arch, Cervical Carotid and Intracranial Arteries in Patients with Embolic Stroke of Undetermined Source. Frontiers in Neurology 13: 968390, July 2022 Notes: (#Corresponding author).
Song JW#, Pavlou A, Xiao J, Kasner SE, Fan Z, Messé SR: Vessel Wall MR Imaging Biomarkers of Symptomatic Intracranial Atherosclerosis: A Meta-Analysis. Stroke 52(1): 193-202, Jan 2021 Notes: (#Corresponding author).
Mattay RR, Saucedo JF, Lehman VT, Xiao J, Obusez EC, Raymond SB, Fan Z, Song JW#.: Current Clinical Applications of Intracranial Vessel Wall MR Imaging. Seminars in Ultrasound, CT, and MRI 42(5): 463-473, Oct 2021 Notes: (#Corresponding author).
Montes D, Vranic J, Lim JC, Song JW, Silverman SB, Gonzalez RG, Romero JM: Cardiovascular Risk Factors Affect Specific Segments of the Intracranial Vasculature in High-Resolution (HR) Vessel Wall Imaging (VWI). Journal of Stroke and Cerebrovascular Diseases 30(10): 106026, Aug 2021.
Song JW#, Cao Q, Siegler JE, Thon JM, Woo JH, Cucchiara BL: Sex-differences in Carotid Plaque Composition in Patients with Embolic Stroke of Undetermined Source. Journal of the American Heart Association 10(9): e020143, May 2021 Notes: (#Corresponding author).
Song JW#, Pavlou A, Burke MP, Shou H, Atsina KB, Xiao J, Loevner LA, Mankoff D, Fan Z, Kasner SE.: Imaging Endpoints of Intracranial Atherosclerosis using Vessel Wall MR Imaging: A Systematic Review. Neuroradiology 63(6): 847-856, Jun 2021 Notes: (#Corresponding author).
Arnett N, Pavlou A, Burke MP, Cucchiara BL, Rhee RL, Song JW: Vessel Wall MR Imaging of Central Nervous System Vasculitis: A Systematic Review. Neuroradiology 64(1): 43-58, Jan 2022 Notes: (#Corresponding author).
Song JW#, Moon BF, Burke MP, Kamesh Iyer S, Elliott MA, Shou H, Messé SR, Kasner SE, Loevner LA, Schnall MD, Kirsch JE, Witschey WR, Fan Z: MR Intracranial Vessel Wall Imaging: A Systematic Review. Journal of Neuroimaging 30(4): 428-442, May 2020 Notes: (#Corresponding author; Review of VWI MR Pulse Sequences and Protocols).
Song JW#, Guiry SC, Shou H, Wang S, Witschey WR, Messé SR, Kasner SE, Loevner LA: Qualitative Assessment and Reporting Quality of Intracranial Vessel Wall MR Imaging Studies: A Systematic Review. AJNR American Journal of Neuroradiology 40(12): 2025-2032, Nov 2019 Notes: (#Corresponding author)
Song JW, Wasserman BA.: Vessel wall MR imaging of Intracranial Atherosclerosis. Cardiovascular Diagnosis and Therapy 10(4): 982-993, Aug 2020.
Song JW#, Obusez EC, Raymond SB, Rafla SD, Schaefer PW, Romero JM: Vessel Wall MRI Added to MR Angiography in the Evaluation of Suspected Vasculopathies. Journal of Neuroimaging 29(4): 454-457. Feb 2019 Notes: (#Corresponding author).
Soun JE, Song JW, Romero JM, Schaefer PW.: Central Nervous System Vasculopathies. Radiologic Clinics of North America 57(6): 1117-1131, July 2019.
Song JW#, Shou H, Obusez EC, Raymond SB, Rafla SD, Kharal GA, Schaefer PW, Romero JM: Spatial Distribution of Intracranial Vessel Wall Enhancement in Hypertension and Primary Angiitis of the CNS. Scientific Reports. Nature Publishing Group, 9(1), Dec 2019 Notes: (#Corresponding author).
Song, JW, Misgeld T, Kang H, Knecht, S, Lu, J, Cao Y, Cotman SL, Bishop DL, Lichtman JW: Lysosomal Activity Associated with Developmental Axon Pruning. Journal of Neuroscience 28(36): 8993-9001, Sep 2008 Notes: (Cover.).
Song, JW: Deja Review: Histology & Medical Cell Biology. McGraw-Hill 2010 Notes: (Editor of book.) ISBN-10: 9780071627269.