Can Ficicioglu

faculty photo
Associate Professor of Pediatrics at the Children's Hospital of Philadelphia
Consultant Physician, Hospital of University of Pennsylvania- Neonatology
Consultant Physician, Pennsylvania Hospital-Neonatology
Department: Pediatrics

Contact information
Division of Human Genetics
The Children's Hospital of Philadelphia
3501 Civic Center Blvd #9054.
Philadelphia, PA 19104
Office: 215 590 3376
Fax: 215 590 4297
Education:
MD
University of Istanbul, Cerrahpasa Medical School ( with High Honors), 1985.
PhD (Histology & Embryology)
University of Marmara, 1996.
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Description of Itmat Expertise

Dr. Ficicioglu is developing algorithms for the effective short and long-term care of patients detected by newborn screening, and new drugs to treat lysosomal storage disorders.

Selected Publications

Ahrens-Nicklas RC, Pyle LC, Ficicioglu C: Morbidity and Mortality Among Exclusively Breastfed Neonates With Medium Chain Acyl-CoA Dehydrogenase Deficiency Genetics in Medicine May 2016.

Bobby G. Ng, Shiryaev S, Rymen D, Eklund E, Raymond K, Kircher M, Abdenur J, Alehan F, Midrob A, Bamshad M, Barone R, Berry G, Brumbaugh, Buckingham K, Clarkson K, Cole S, O'Connor S, Cooper GM, Van Coster R, Demmer L, Diogo L, Fay A, Ficicioglu C, Fiumara , Gahl WA, Ganetzky G, Goel H, Harshman L, He M, Jaeken J, Lachlan K , Lam C , Yaplito-Lee J, Nickerson D , Peters H, Race V, Régal L, Rush J, Rutledge S, Shendure S, Sparks S, Trapane P, Sanchez-Valle A, Vilain E, Waechter C, Wang R, Wolfe L, Wong DA, Wood T, Yang AC , Matthijs G , Freeze HH: ALG1-CDG: Clinical and molecular characterization of 39 unreported patients. Human Mutations March 2016.

Weber DR, Coughlin II C, Brodsky JL, Lindstrom K, Ficicioglu C, Kaplan P, Freehauf CL, Levine MA : Low Bone Mineral Density is a Common Finding in Patients with Homocystinuria Molecular Genetics and Metabolism December 2015.

Burton B, Balwani M , Francois F, Baric I, Burrow A, Grande C, Coker M, Sánchez A, Deegan P, Di Rocco M, Enns G, Erbe R, Ezgu F, Ficicioglu C, Furuya K, Kane J, Laukaitis C, Mengel E, Neilan E, Nightingale S, Peters H, Scarpa M, Schwab K, Smolka V, Valayannopoulos V, Wood M, Goodman Z, Yang Y, Eckert S, Rojas-Caro S, Quinn A.: A Phase 3 Trial of Sebelipase Alfa in Lysosomal Acid Lipase Deficiency. N Engl J Med. 373(11): 1010-20, September 2015.

Chien Y, Bannick A, Corrales F,Couce M, Donner M, Ficicioglu C et al : Mudd's disease (MATI/III deficency). A survey data for MAT1A homozygotes and compound heterzygotes. Orphanet Journal of Rare Disease 10(1): 99, August 2015.

Longo N, Arnold GL, Pridjian G, Enns GM, Ficicioglu C, Parker S, Cohen-Pfeffer JL.: Long-Term Safety and Efficacy of Sapropterin: the PKUDOS registry experience. Molecular Genetics and Metabolism February 2015.

Bonafede L, Ficicioglu CH, Serrano L, Han G, Morgan JIW , Mills M, Forbes, BJ, Davidson, S, Binenbaum G , Nichols CH, Kaplan P, Verloo P, Leroy BP, Maguire AM , Aleman TS: Cobalamin C Deficiency Shows a Rapidly Progressing Maculopathy with Severe Photoreceptor and Ganglion Cell Los. Investigative Ophthalmology & Visual Science (IOVS)(56), 7875-7887, 2015.

Aleman TS, Brodie F, Garvin C, Gewaily DY, Ficicioglu CH, Mills MD, Forbes BJ, Maguire AM, Davidson SL.: Retinal Structure in Cobalamin C Disease: Mechanistic and Therapeutic Implications. Ophthalmic Genet. February 2014

Chadwick S, Fitzgerald K, Weiss B, Ficicioglu C: Thirteen patients with MAT1A mutations detected through newborn screening: 13 years experience JIMD reports January 2014.

Tegtmeyer L, Rust S, van Scherpenzeel M, Bobby G. Ng BG, Losfeld ME, Timal S, Raymond K, He P, Ichikawa M, Veltman J, Huijben K, Shin YS, Sharma V, Adamowicz M, Lammens M, Reunert J, Witten A, Schrapers E, Matthijs G, Jaeken J, Rymen D, Stojkovic T, Pascal Laforêt P, Petit P, Aumaître O, Czarnowska E, Piraud M, Podskarbi T, Stanley CA, Matalon R, Burda P, Seyyedi S, Debus V, Socha P, Sykut-Cegielska J, van Spronsen F, de Meirleir L, Vajro P, DeClue T, Ficicioglu C, Wada Y, Wevers RA, Vanderschaeghe D, Callewaert N, Fingerhut R, van Schaftingen E, Freeze HH, Morava E, Lefeber DJ, Marquardt T.: Multiple Phenotypes in Phosphoglucomutase 1 Deficiency. N Engl J Med (370), 533-542, 2014.

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Last updated: 05/27/2016
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