Janet L Kwiatkowski

faculty photo
Associate Professor of Pediatrics at the Children's Hospital of Philadelphia
Consulting Hematologist, Hospital of the University of Pennsylvania
Consulting Hematologist, Pennsylvania Hospital
Director, Thalassemia Program, Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
The Children's Hospital of Philadelphia
Division of Hematology
3401 Civic Center Blvd
Colket Translational Research Building, Room 11024
Philadelphia, PA 19104
Office: 215-590-5286
B.S. (Zoology)
Duke University, summa cum laude, 1988.
Columbia University, College of Physicians & Surgeons, 1992.
MSCE (Clinical Epidemiology and Biostatistics)
University of Pennsylvania, 2003.
Permanent link

Description of Research Expertise

Optimization of iron chelation, monitoring transfusional iron overload, stroke prevention in sickle cell disease, headaches in sickle cell disease, complications of thalassemia, transfusion therapy

Description of Itmat Expertise

The research interests of Dr. Kwiatkowski include stroke and stroke prevention in sickle cell disease, transfusional iron overload and chelation therapy, and diagnosis and treatment of clinical complications of thalassemia.

Selected Publications

Stanley Helen M, Friedman David F, Webb Jennifer, Kwiatkowski Janet L: Transfusional Iron Overload in a Cohort of Children with Sickle Cell Disease: Impact of Magnetic Resonance Imaging, Transfusion Method, and Chelation. Pediatric Blood & Cancer 63(8): 1414-8, Aug 2016.

Nabavizadeh SA, Vossough A, Ichord RN, Kwiatkowski J, Pukenas BA, Smith MJ, Storm PB, Zager EL, Hurst RW: Intracranial aneursyms in sickle cell anemia: clinical and imaging findings. Journal of Neurointerventiaonal Surgery 8(4): 434-40, April 2016.

Kwiatkowski Janet L: Current recommendations for chelation for transfusion-dependent thalassemia. Annals of the New York Academy of Sciences 1368(1): 107-14, Mar 2016.

Ware Russell E, Davis Barry R, Schultz William H, Brown R Clark, Aygun Banu, Sarnaik Sharada, Odame Isaac, Fuh Beng, George Alex, Owen William, Luchtman-Jones Lori, Rogers Zora R, Hilliard Lee, Gauger Cynthia, Piccone Connie, Lee Margaret T, Kwiatkowski Janet L, Jackson Sherron, Miller Scott T, Roberts Carla, Heeney Matthew M, Kalfa Theodosia A, Nelson Stephen, Imran Hamayun, Nottage Kerri, Alvarez Ofelia, Rhodes Melissa, Thompson Alexis A, Rothman Jennifer A, Helton Kathleen J, Roberts Donna, Coleman Jamie, Bonner Melanie J, Kutlar Abdullah, Patel Niren, Wood John, Piller Linda, Wei Peng, Luden Judy, Mortier Nicole A, Stuber Susan E, Luban Naomi L C, Cohen Alan R, Pressel Sara, Adams Robert J: Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial. Lancet (London, England) 387(10019): 661-70, Feb 2016.

Luchtman-Jones Lori, Pressel Sara, Hilliard Lee, Brown R Clark, Smith Mary G, Thompson Alexis A, Lee Margaret T, Rothman Jennifer, Rogers Zora R, Owen William, Imran Hamayun, Thornburg Courtney, Kwiatkowski Janet L, Aygun Banu, Nelson Stephen, Roberts Carla, Gauger Cynthia, Piccone Connie, Kalfa Theodosia, Alvarez Ofelia, Hassell Kathryn, Davis Barry R, Ware Russell E: Effects of hydroxyurea treatment for patients with hemoglobin SC disease. American Journal of Hematology 91(2): 238-42, Feb 2016.

Wood John C, Cohen Alan R, Pressel Sara L, Aygun Banu, Imran Hamayun, Luchtman-Jones Lori, Thompson Alexis A, Fuh Beng, Schultz William H, Davis Barry R, Ware Russell E: Organ iron accumulation in chronically transfused children with sickle cell anaemia: baseline results from the TWiTCH trial. British Journal of Haematology 172(1): 122-30, Jan 2016.

Adams RJ, Lackland DT, Brown L, Brown D, Voeks J, Fullerton HJ, Kanter J and Kwiatkowski JL: Transcranial Doppler Re-Screening of Subjects who Participated in STOP and STOP II. American Journal of Hematology in press 2016.

Grace RF, RoseC, Layton, DM, Barcellini JL, Silver B, Merica E, Kung C, Cohen M, Yang H, Hixon J, Kosinski PA, Silverman L, Dang L, Yuan AJ Barbier AJ, Agresta S, Glader B: Effects of AG-348, a Pyruvate Kinase Activator, on Anemia and Hemolysis in Patients with Pyruvate Kinase Deficiency: Early Data from the Drive PK Study. European Hematology Association, Annual Meeting 2016 Notes: oral presentation given by collaborator.

Dowling MM, QuinnCT, Ramaciotti C, Kanter J, Osunkwo I, Inusa B, Iyer R, Kwiatkowski JL, Johnson C, Rhodes M, Owen W, Strouse JJ, Panepinto JA, Neumayr L, Sarnaik S, Plumb PA, Diamini N, Kirkham F, Hynan LS, PFAST Investigators: Increased prevalence of potential right-to-left shunting in children with sickle cell anaemia and stroke. British Journal of Haematology in press, 2016.

Kwiatkowski, JL: Hemoglobinopathies. Manual of Pediatric Hematology and Oncology, 6th Edition. Elsevier, London, UK, 2016.

back to top
Last updated: 11/15/2016
The Trustees of the University of Pennsylvania