Janet L Kwiatkowski

faculty photo
Associate Professor of Pediatrics at the Children's Hospital of Philadelphia
Consulting Hematologist, Hospital of the University of Pennsylvania
Consulting Hematologist, Pennsylvania Hospital
Director, Thalassemia Program, Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
The Children's Hospital of Philadelphia
Division of Hematology
3401 Civic Center Blvd
Colket Translational Research Building, Room 11024
Philadelphia, PA 19104
Office: 215-590-5286
B.S. (Zoology)
Duke University, summa cum laude, 1988.
Columbia University, College of Physicians & Surgeons, 1992.
MSCE (Clinical Epidemiology and Biostatistics)
University of Pennsylvania, 2003.
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Description of Research Expertise

Optimization of iron chelation, monitoring transfusional iron overload, stroke prevention in sickle cell disease, headaches in sickle cell disease, complications of thalassemia, transfusion therapy

Description of Itmat Expertise

The research interests of Dr. Kwiatkowski include stroke and stroke prevention in sickle cell disease, transfusional iron overload and chelation therapy, and diagnosis and treatment of clinical complications of thalassemia.

Selected Publications

Thompson A, Walters M, Kwiatkowski J, Ribeil J-A, Rasko J, Hongeng S, Magrin E, Schiller G, Payen E, Semeraro M, Moshous D, Lefrere F, Puy H, Magnani A, Caccavelli L, Diana J-S, Suarez F, Monpoux F, Brouse V, Poirot C, Brouzes C, Meritet, J-F, Pondarre C, Buezard Y, Chretien S, Lefebvre T, Teachey D, Anurathapan U, Ho P, von Kalle C, Kletzel M, Vichinsky E, Soni S, Veres G, Negre O, Ross R, Davidson D, Petrusich A, Sandler L, Asmal M, Hermine O, de Montalembert M, Blanche S, Leboulch P, Cavazzano-Calvo M: Gene Therapy for Transfusion-Dependent Beta-thalassemia. New England Journal of Medicine 2018 Notes: in press.

Kwiatkowski JL: Thalassemia minor. Case Studies in Hematology & Coagulation. Gulati G, Filicko-O'Hara J, Krause JJ (eds.). American Society for Clinical Pathology Press, 2nd edition, 2017 (in press).

Kwiatkowski JL: Beta Thalassemia Major. Case Studies in Hematology & Coagulation. Gulati G, Filicko-O'Hara J, Krause JR (eds.). American Society for Clinical Pathology Press, 2nd edition, 2017 (in press).

Belmont Ami, Kwiatkowski Janet L: Deferiprone for the treatment of transfusional iron overload in thalassemia. Expert Review of Hematology 10(6): 493-503, Jun 2017.

Lambert Michele P, Witmer Char M, Kwiatkowski Janet L: Therapy induced iron deficiency in children treated with eltrombopag for immune thrombocytopenia. American Journal of Hematology 92(6): E88-E91, Jun 2017.

Hamm J, Rathore N, Lee P, LeBlanc Z, Lebensburger J, Meier ER, Kwiatkowski, JL: Cranial Epidural Hematomas: A Case Series and Literature Review of This Rare Complication Associated with Sickle Cell Disease. Pediatric Blood & Cancer 64(3): e26237, March 2017.

Dowling MM, QuinnCT, Ramaciotti C, Kanter J, Osunkwo I, Inusa B, Iyer R, Kwiatkowski JL, Johnson C, Rhodes M, Owen W, Strouse JJ, Panepinto JA, Neumayr L, Sarnaik S, Plumb PA, Diamini N, Kirkham F, Hynan LS, PFAST Investigators: Increased prevalence of potential right-to-left shunting in children with sickle cell anaemia and stroke. British Journal of Haematology 176(2): 300-308, January 2017.

Grace RF, Layton DM, Galacteros F, Rose C, Barcellini W, Morton DH, Van Beers EJ, Yaish HM, Ravindranath Y, Kuo, KHM, Sheth S, Kwiatkowski JL, Silver B, Kung C, Cohen M, Yang H, Kosinski PA, Hua L, Barbier A, Glader B: Results update from the DRIVE PK study: effects of AG-348, a pyruvate kinase activator, in patients with pyruvate kinase deficiency. Blood 130: 2194, 2017 Notes: Poster presentation by collaborator.

Kanter J, Walters MC, Hsieh M, Krishnamurti L, Kwiatkowski JL, Kamble R, von Kalle C, Joseney-Antoine M, Pierciey FJ, Jr, Shi W, Asmal M, Thompson AA, Tisdale JF: Interim results from a phase 1/2 clinical study of lentiglobin gene therapy for severe sickle cell disease. Blood 130: 527, 2017 Notes: Oral presentation by collaborator.

Walters MC, Hongeng S, Kwiatkowski JL, Locatelli F, Porter JB, Sauer MG, Thrasher AJ, Thuret I, Yannaki E, Eliot H, Gayron M, Asmal M, Thompson AA: Results from the Hgb-207 (Northstar-2) trial: a phase 3 study to evaluate safety and efficacy of lentiglobin gene therapy for transfusion-dependent beta thalassemia (TDT) in patients with non-beta0/beta0 genotypes. blood 130: 526, 2017 Notes: Oral presentation by collaborator.

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Last updated: 01/17/2018
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