Gary Warren Falk

faculty photo
Professor of Medicine at the Hospital of the University of Pennsylvania
Adjunct Faculty, Center for Clinical Epidemiology and Biostatistics
Clinical Co-Director, Joint Center for Digestive, Liver and Pancreatic Medicine, University of Pennsylvania, School of Medicine and the Children's Hospital of Philadelphia
Co-Director, GI Motility/Physiology Program, Hospital of the University of Pennsylvania, and Perelman Center for Advanced Medicine
Co-director, Joint Penn CHOP Center for Digestive, Liver and Pancreatic Disorders.
Co-director, GI Physiology Laboratory. Hospital of the University of Pennsylvania.
Member, Abramson Comprehensive Cancer Center. Cancer Control Research Program. Hospital of the University of Pennsylvania.
University Associate Staff. , Children's Hospitalof Philadlephia
Department: Medicine

Contact information
Division of Gastroenterology
Department of Internal Medicine
Hospital of the University of Pennsylvania
7th Floor South Pavilion
Perelman Center for Advanced Medicine
3400 Civic Center Drive
Philadelphia, PA 19104
Office: 215-615-4951
Fax: 215-349-5915
Education:
HS
Stuyvesant High School, New York, New York , 1972.
B.S. (Biology-Geology. Cum laude with high distinction)
University of Rochester, Rochester, NY, 1976.
M.D.
University of Rochester School of Medicine and Dentistry, Rochester, NY, 1980.
M.S. (Clinical Research)
Case Western Reserve University School of Medicine Clinical Scholars Program, Cleveland, Ohio, 2006.
Permanent link
 

Description of Itmat Expertise

Barrett's esophagus-early detection and prevention

Eosinophilic esophagitis: childhood-> adult transitions; effect of immune modulators on motility and fibrosis

Description of Other Expertise

Consultative gastroenterology
Upper endosccopy
Endoscopic dilation
Endoscopic mucosal resection
Radiofrequency ablation
Pneumatic dilation
Colonoscopy
Polypectomy
High resolution manometry
BRAVO pH
Impedance pH
Hydrogen breath tests
Urea breath tests

Description of Research Expertise

Barrett's esophagus: chemoprevention, detection, diagnosis, cancer prevention, epidemiology, risk stratification, pathogenesis

Eosinophilic esophagitis: epidemiology, pediatric-adult transition, fibrosis, clinical trials, pathogenesis

Endoscopy: advanced imaging

Selected Publications

Kong Jianping, Whelan Kelly A, Laczkó Dorottya, Dang Brendan, Caro Monroig Angeliz, Soroush Ali, Falcone John, Amaravadi Ravi K, Rustgi Anil K, Ginsberg Gregory G, Falk Gary W, Nakagawa Hiroshi, Lynch John P: Autophagy levels are elevated in barrett's esophagus and promote cell survival from acid and oxidative stress. Molecular carcinogenesis Sep 2015.

Del Portillo Armando, Lagana Stephen M, Yao Yuan, Uehara Takeshi, Jhala Nirag, Ganguly Tapan, Nagy Peter, Gutierrez Jorge, Luna Aesis, Abrams Julian, Liu Yang, Brand Randall, Sepulveda Jorge L, Falk Gary W, Sepulveda Antonia R: Evaluation of Mutational Testing of Preneoplastic Barrett's Mucosa by Next-Generation Sequencing of Formalin-Fixed, Paraffin-Embedded Endoscopic Samples for Detection of Concurrent Dysplasia and Adenocarcinoma in Barrett's Esophagus. The Journal of molecular diagnostics : JMD 17(4): 412-9, Jul 2015.

Bennett Cathy, Moayyedi Paul, Corley Douglas A, DeCaestecker John, Falck-Ytter Yngve, Falk Gary, Vakil Nimish, Sanders Scott, Vieth Michael, Inadomi John, Aldulaimi David, Ho Khek-Yu, Odze Robert, Meltzer Stephen J, Quigley Eamonn, Gittens Stuart, Watson Peter, Zaninotto Giovanni, Iyer Prasad G, Alexandre Leo, Ang Yeng, Callaghan James, Harrison Rebecca, Singh Rajvinder, Bhandari Pradeep, Bisschops Raf, Geramizadeh Bita, Kaye Philip, Krishnadath Sheila, Brian Fennerty M, Manner Hendrik, Nason Katie S, Pech Oliver, Konda Vani, Ragunath Krish, Rahman Imdadur, Romero Yvonne, Sampliner Richard, Siersema Peter D, Tack Jan, Tham Tony C K, Trudgill Nigel, Weinberg David S, Wang Jean, Wang Kenneth, Wong Jennie Y Y, Attwood Stephen, Malfertheiner Peter, MacDonald David, Barr Hugh, Ferguson Mark K, Jankowski Janusz: Addendum: BOB CAT: A Large-Scale Review and Delphi Consensus for Management of Barrett's Esophagus With No Dysplasia, Indefinite for, or Low-Grade Dysplasia. The American journal of gastroenterology 110(6): 943, Jun 2015.

Yachimski Patrick, Maqbool Sabba, Bhat Yasser M, Richter Joel E, Falk Gary W, Vaezi Michael F: Control of Acid and Duodenogastroesophageal Reflux (DGER) in Patients With Barrett's Esophagus. The American journal of gastroenterology 110(8): 1143-8, Jun 2015.

Bennett Cathy, Moayyedi Paul, Corley Douglas A, DeCaestecker John, Falck-Ytter Yngve, Falk Gary, Vakil Nimish, Sanders Scott, Vieth Michael, Inadomi John, Aldulaimi David, Ho Khek-Yu, Odze Robert, Meltzer Stephen J, Quigley Eamonn, Gittens Stuart, Watson Peter, Zaninotto Giovanni, Iyer Prasad G, Alexandre Leo, Ang Yeng, Callaghan James, Harrison Rebecca, Singh Rajvinder, Bhandari Pradeep, Bisschops Raf, Geramizadeh Bita, Kaye Philip, Krishnadath Sheila, Fennerty M Brian, Manner Hendrik, Nason Katie S, Pech Oliver, Konda Vani, Ragunath Krish, Rahman Imdadur, Romero Yvonne, Sampliner Richard, Siersema Peter D, Tack Jan, Tham Tony C K, Trudgill Nigel, Weinberg David S, Wang Jean, Wang Kenneth, Wong Jennie Y Y, Attwood Stephen, Malfertheiner Peter, MacDonald David, Barr Hugh, Ferguson Mark K, Jankowski Janusz: BOB CAT: a Large-Scale Review and Delphi Consensus for Management of Barrett's Esophagus With No Dysplasia, Indefinite for, or Low-Grade Dysplasia. The American journal of gastroenterology 110(5): 662-82; quiz 683, May 2015.

Small Aaron J, Sutherland Scott E, Hightower Jessica S, Guarner-Argente Carlos, Furth Emma E, Kochman Michael L, Forde Kimberly A, Bewtra Meenakshi, Falk Gary W, Ginsberg Gregory G: Comparative risk of recurrence of dysplasia and carcinoma after endoluminal eradication therapy of high-grade dysplasia versus intramucosal carcinoma in Barrett's esophagus. Gastrointestinal endoscopy 81(5): 1158-66.e1-4, May 2015.

Chandrasekhara Vinay, Desilets David, Falk Gary W, Inoue Haruhiro, Romanelli John R, Savides Thomas J, Stavropoulos Stavros N, Swanstrom Lee L: The American Society for Gastrointestinal Endoscopy PIVI (Preservation and Incorporation of Valuable Endoscopic Innovations) on peroral endoscopic myotomy. Gastrointestinal endoscopy 81(5): 1087-100.e1, May 2015.

Small Aaron J, Araujo James L, Leggett Cadman L, Mendelson Aaron H, Agarwalla Anant, Abrams Julian A, Lightdale Charles J, Wang Timothy C, Iyer Prasad G, Wang Kenneth K, Rustgi Anil K, Ginsberg Gregory G, Forde Kimberly A, Gimotty Phyllis A, Lewis James D, Falk Gary W, Bewtra Meenakshi: Radiofrequency Ablation Is Associated With Decreased Neoplastic Progression in Patients With Barrett's Esophagus and Confirmed Low-Grade Dysplasia. Gastroenterology 149(3): 567-576.e3, Apr 2015.

Jiang Ming, Ku Wei-Yao, Zhou Zhongren, Dellon Evan S, Falk Gary W, Nakagawa Hiroshi, Wang Mei-Lun, Liu Kuancan, Wang Jun, Katzka David A, Peters Jeffrey H, Lan Xiaopeng, Que Jianwen: BMP-driven NRF2 activation in esophageal basal cell differentiation and eosinophilic esophagitis. The Journal of clinical investigation 125(4): 1557-68, Apr 2015.

Sinh Preetika, Anaparthy Rajeswari, Young Patrick E, Gaddam Srinivas, Thota Prashanthi, Balasubramanian Gokulakrishnan, Singh Mandeep, Higbee April D, Wani Sachin, Gupta Neil, Rastogi Amit, Mathur Sharad C, Bansal Ajay, Horwhat John D, Cash Brooks D, Falk Gary W, Lieberman David A, Vargo John J, Sampliner Richard E, Sharma Prateek: Clinical outcomes in patients with a diagnosis of "indefinite for dysplasia" in Barrett's esophagus: a multicenter cohort study. Endoscopy 47(8): 669-74, Apr 2015.

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Last updated: 09/26/2015
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