Peter D. Le Roux
Associate Professor of Neurosurgery
Attending, Neurosurgery, Pennsylvania Hospital, Philadelphia, PA
Attending, Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia, PA
Attending, Neurosurgery, Philadelphia VAMC, Philadelphia, PA
University Associate, Neurosurgery, Children’s Hospital of Philadelphia, Philadelphia, PA
Department: Neurosurgery
Contact information
Department of Neurosurgery
Pennsylvania Hospital
Washington Square West Building
235 S. 8th Street
Philadelphia, PA 19106
Pennsylvania Hospital
Washington Square West Building
235 S. 8th Street
Philadelphia, PA 19106
Office: 215-829-6700
Fax: 215-829-6645
Fax: 215-829-6645
Email:
peter.leroux@uphs.upenn.edu
peter.leroux@uphs.upenn.edu
Education:
MB., ChB
University of Cape Town, South Africa, 1983.
University of Cape Town, South Africa , 1983.
MD
University of Cape Town, South Africa, 1995.
Permanent linkMB., ChB
University of Cape Town, South Africa, 1983.
University of Cape Town, South Africa , 1983.
MD
University of Cape Town, South Africa, 1995.
Description of Itmat Expertise
Brain oxygen and metabolismTBI - pathophysiology and recovery
Brain resuscitation
Dendrite growth and pathology
GABergic cell function
Glutamate receptors
Selected Publications
Brewer GJ, LeRoux PD: Human primary brain tumor cell growth inhibition in serum-free medium optimized for neuron survival. Brain Res 1157: 156-166, Jul 2007.Pascual JL, Maloney-Wilensky E, Reilly PM, Sicoutris C, Keutmann MK, Stein SC, Leroux PD, Gracias VH: Resuscitation of hypotensive head-injured patients: Is hypertonic saline the answer? Am Surgeon 74(3): 253-259, Mar 2008.
Stiefel MF, Zaghloul KA, Bloom S, Gracias VH, LeRoux PD: Improved Cerebral Oxygenation following Inhaled Aerosolized Prostacyclin Therapy for Acute Lung Injury: A Case Report. J Trauma 63(5): 1155-1158, Nov 2007.
Monnerie H, LeRoux PD: Reduced dendrite growth and altered glutamic acid decarboxylase (GAD) 65- and 67-kDa isoform protein expression from mouse cortical GABAergic neurons following excitotoxic injury in vitro. Exp Neurol 205(2): 367-382, Jun 2007.
Nagpal S, Halpern C, Sims C, Gracias V, Schuster J, Le Roux P, Levin J: Decompressive laparotomy to treat intractable cerebral hypoxia. J Trauma in press 2007.
Figaji AA, Fieggen AG, Sandler S, Argent AC, Le Roux PD, Peter JC. : Intracranial Pressure and Cerebral Oxygenation Changes after Decompressive Craniectomy in a Child with Traumatic Brain Swelling. Childs Nervous System in press 2007.
Smith ML, Counelis GJ, Maloney-Wilensky E, Stiefel M, Donley K, LeRoux PD: Brain tissue oxygen tension in clinical brain death: a case series. Neurol Res 29(7): 755-759, Oct 2007.
Elmariah SB, Huse J, Mason B, Le Roux P, Lustig RA.: Multicentric Glioblastoma Multiforme in a Patient with BRCA-1 Invasive Breast Cancer. Breast J 12(5): 470-4, 2006.
Stiefel MF, Udoetek J, Spiotta A, Gracias VH, Goldberg AH, Maloney-Wilensky E, Bloom S, Le Roux P: Conventional Neurocritical Care and Cerebral Oxygenation after Traumatic Brain Injury. J Neurosurgery 105: 568-575, 2006.
Monnerie H, Le Roux P: Kainate-induced non-NMDA receptor activation enhances dendrite growth from mouse cortical neurons in vitro. J. Neurosci Res 83: 944-956, 2006.