faculty photo

Anne Rentoumis Cappola

Associate Professor of Medicine
Department: Medicine

Contact information
Division of Endocrinology, Diabetes, and Metabolism
Room 12-136
Smilow Center for Translational Research, 12th floor
3400 Civic Center Blvd., Building 421
Philadelphia, PA 19104-5160
Office: (215) 573-5359
Fax: (215) 898-5408
Graduate Group Affiliations
B.A. (Biochemistry )
Harvard College (Advanced Standing), Cambridge, MA, 1990.
University of Pennsylvania School of Medicine, 1994.
Sc.M. (Clinical Epidemiology)
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 2001.
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Description of Research Expertise

Anne Rentoumis Cappola, M.D., Sc.M. is an Associate Professor of Medicine in the Division of Endocrinology, Diabetes, and Metabolism, Associate Scholar in the Center for Clinical Epidemiology (CCEB), Core Faculty Member of the Master's in Translational Research program, and a Fellow in the Institute on Aging. She is an Associate Editor for the Journal of the American Medical Association (JAMA).

Dr. Cappola's research focuses on the hormonal alterations that occur with aging and the clinical impact of these changes. She is funded by the National Institute on Aging. Current projects include studies of the indications for treatment of subclinical thyroid dysfunction in older men and women; the role of androgens in the health of older women; hormonal treatments for the frailty syndrome; and metabolic changes in men and women who sustain a hip fracture.

Selected Publications

Cappola AR, Arnold AM, Wulczyn K, Carlson M, Robbins J, Psaty BM: Thyroid function in the euthyroid range and adverse outcomes in older adults. J Clin Endocrinol Metab 100(3): 1088-96, Mar 2015.

Åsvold BO, Vatten LJ, Bjøro T, Bauer DC, Bremner A, Cappola AR, Ceresini G, den Elzen WPJ, Ferrucci L, Franco OH, Franklyn JA, Gussekloo J, Iervasi G Imaizumi M, Kearney PM, Khaw KT, Newman AB, Peeters RP, Psaty BM, Razvi S, Sgarbi JA, Stott DK, Trompet S, Vanderpump MP, Völzke H, Walsh JP, Westendorp RG, Rodondi N, for the Thyroid Studies Collaboration: Thyroid function within the normal range and risk of coronary heart disease. JAMA-Internal Medicine In press 2015.

Corriere MD, Yao W, Xue QL, Cappola AR, Fried LP, Thorpe RJ, Szanton SL, Kalyani RR : The association of neighborhood characteristics with obesity and metabolic conditions in older women. JNHA 18(9): 792-8, Dec 2014.

Maggio M, Snyder PJ, De Vita F, Ceda GP, Milaneschi Y, Lauretani F, Luci M, Cattabiani C, Peachey H, Valenti G, Cappola AR, Longo DL, Ferrucci L: Effects of transdermal testosterone treatment on inflammatory markers in elderly men. Endocr Pract 20(11): 1170-7, Nov 2014.

Shores MM, Arnold AM, Biggs ML, Longstregth WT, Smith NL, Kizer JR, Cappola AR, Hirsch CH, Marck BT, Matsumoto AM: Testosterone and dihydrotestosterone and incident ischemic stroke in men in the Cardiovascular Health Study. Clin Endocrinol 81(5): 746-53, Nov 2014.

Collet TH, Bauer DC, Cappola AR, Åsvold BO, Weiler S, Vittinghoff E, Gussekloo J, Bremner A, den Elzen WP, Maciel RMB, Vanderpump MP, Cornuz J, Dörr M, Wallaschofski H, Newman AB, Sgarbi JA, Razvi S, Völzke H, Walsh JP, Aujesky D, Rodondi N, for the Thyroid Studies Collaboration: Thyroid antibody status, subclinical hypothyroidism and the risk of coronary heart disease - An individual participant data analysis. J Clin Endocrinol Metab 99(9): 3353-62, Sep 2014.

Garin MC, Arnold AM, Lee JS, Robbins J, Cappola AR: Subclinical thyroid dysfunction and hip fracture and bone mineral density in older adults: the Cardiovascular Health Study. J Clin Endocrinol Metab 99(8): 2657-64, Aug 2014.

Chen CT, Liu CT, Chen GK, Andrews JS, Arnold AM, Dreyfus J, Franceschini N, Garcia ME, Kerr KF, Li G, Lohman KK, Musani SK, Nalls MA, Raffel LJ, Smith J, Ambrosone CB, Bandera EV, Bernstein L, Britton A, Brzyski RG, Cappola A, Carlson CS, Couper D, Deming SL, Goodarzi MO, Heiss G, John EM, Lu X, Le Marchand L, Marciante K, McKnight B, Millikan R, Nock NL, Olshan AF, Press MF, Vaiyda D, Woods NF, Taylor HA, Zhao W, Zheng W, Evans MK, Harris TB, Henderson BE, Kardia SL, Kooperberg C, Liu Y, Mosley TH, Psaty B, Wellons M, Windham BG, Zonderman AB, Cupples LA, Demerath EW, Haiman C, Murabito JM, Rajkovic A: Meta-analysis of loci associated with age at natural menopause in African-American women. Hum Mol Genet 23(12): 3327-42, Jun 2014.

Shores MM, Biggs ML, Arnold AM, Smith NL, Longstreth WT, Kizer JR, Hirsch CH, Cappola AR, Matsumoto AM: Testosterone, dihydrotestosterone and incident cardiovascular disease and mortality in the Cardiovascular Health Study. J Clin Endocrinol Metab 99(6): 2061-68, Jun 2014.

Mariani LH, White MT, Shults J, Anderson CA, Feldman HI, Wolf M, Reese PP, Denburg MR, Townsend RR, Lo JC, Cappola AR, Carlow D, Gadegbeku CA, Steigerwalt S, Leonard MB; CRIC Study Investigators: Increasing use of vitamin D supplementation in the Chronic Renal Insufficiency Cohort Study. J Ren Nutr 24(3): 186-93, May 2014.

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Last updated: 03/18/2015
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