faculty photo

Anne Rentoumis Cappola

Associate Professor of Medicine
Department: Medicine

Contact information
Division of Endocrinology, Diabetes, and Metabolism
Room 12-136
Translational Research Center, 12th floor
3400 Civic Center Blvd., Building 421
Philadelphia, PA 19104-5160
Office: (215) 573-5359
Fax: (215) 898-5408
Graduate Group Affiliations
Education:
B.A. (Biochemistry )
Harvard College (Advanced Standing), Cambridge, MA, 1990.
M.D.
University of Pennsylvania School of Medicine, 1994.
Sc.M. (Clinical Epidemiology)
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 2001.
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Description of Research Expertise

Anne Rentoumis Cappola, M.D., Sc.M. is an Associate Professor of Medicine in the Division of Endocrinology, Diabetes, and Metabolism, Associate Scholar in the Center for Clinical Epidemiology (CCEB), Core Faculty Member of the Master's in Translational Research program, and a Fellow in the Institute on Aging. She is a Contributing Editor for the Journal of the American Medical Association (JAMA).

Dr. Cappola's research focuses on the hormonal alterations that occur with aging and the clinical impact of these changes. She is funded by the National Institute on Aging. Current projects include studies of the indications for treatment of subclinical thyroid dysfunction in older men and women; the role of androgens in the health of older women; hormonal treatments for the frailty syndrome; and metabolic changes in men and women who sustain a hip fracture.

Selected Publications

Hyland KA, Arnold AM, Lee JS, Cappola AR: Persistent subclinical hypothyroidism and cardiovascular risk in the elderly: the Cardiovascular Health Study. J Clin Endocrinol Metab Jan 2013.

Kalyani RR, Varadhan R, Weiss CO, Fried LP, Cappola AR: Frailty status and altered glucose-insulin dynamics J Gerontol A Biol Sci Med Sci 67(12): 1300-6, Dec 2012.

Waring AC, Arnold AM, Newman AB, Bůžková P, Hirsch C, Cappola AR: Longitudinal changes in thyroid function in the oldest old and survival: the Cardiovascular Health Study All-Stars Study. J Clin Endocrinol Metab 97(11): 3944-50, Nov 2012.

Speck RM, Sammel MD, Troxel AB, Cappola AR, Williams-Smith CT, Chittams J, Scott P, Tuton LW, Abbuhl SB: Factors impacting the departure rates of female and male junior medical school faculty: evidence from a longitudinal analysis J Women's Health 21(10): 1059-65, Oct 2012.

Weiss CO, Cappola AR, Varadhan R, Kim K, Fried LP: Resting metabolic rate among old-old women with and without frailty: Variability and estimation of energy requirement. J Am Geriatr Soc 60(9): 1695-700, Sep 2012.

Kalyani RR, Tian J, Xue QL, Walston J, Cappola AR, Fried LP, Brancati FL, Blaum CS: Hyperglycemia and incidence of frailty and lower extremity mobility limitations in older women. J Am Geriatr Soc 60(9): 1701-7, Sep 2012.

Gencer B, Collet TH, Virgini V, Bauer DC, Gussekloo J, Cappola AR, Nanchen D, den Elzen WP, Balmer P, Luben RN, Iocaviello M, Triggiani V, Cornuz J, Newman AB, Khaw KT, Jukema JW, Westendorp RG, Vittinghoff E, Aujesky D, Rodondi N; for the Thyroid Studies Collaboration.: Subclinical thyroid dysfunction and the risk of heart failure events: an individual participant data analysis from six prospective cohorts. Circulation 126(9): 1040-9, Aug 2012.

Crasto CL, Semba RD, Sun K, Cappola AR, Bandinelli S, Ferrucci L : Relationship of low circulating “anti-aging” klotho hormone with disability in activities of daily living among older community-dwelling adults. Rejuv Res 15(3): 295-301, Jun 2012.

Kaplan R, Buzkova P, Cappola AR, Strickler HD, McGinn AP, Mercer LD, Arnold AM, Pollak MN, Newman AB: Decline in circulating insulin-like growth factors and mortality in older adults: Cardiovascular Health Study All-Stars Study. J Clin Endocrinol Metab 97(6): 1970-6, Jun 2012.

Somwaru LL, Rariy CM, Arnold AM, Cappola AR: The natural history of subclinical hypothyroidism in the elderly: the Cardiovascular Health Study. J Clin Endocrinol Metab 97(6): 1962-9, Jun 2012.

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Last updated: 11/27/2012
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