Dr. Dunbar is interested in atherogenic dyslipidemia and its treatment, and has particular expertise in the mechanism of action and adverse effects of nicotinic acid (niacin). He has developed sophisticated objective techniques to quantify the physical stigmata of flushing from niacin. He combines these techniques with laboratory pharmacodynamic studies to elucidate the integrated physiology of the response to niacin.
Dr. Dunbar specializes in the treatment of cholesterol disorders, and practices in the Preventive Cardiology Clinic at the Pereleman Center for Advanced Medicine
Selected Publications
Dunbar RL, Cuchel M, Millar JS, Baer A, Poria R, Freifelder RH, Pryma DA, Billheimer JJ, Rader DJ: Niacin Does Not Accelerate Reverse Cholesterol Transport in Man [Poster Presentation] ATVB April 2013 Notes: Arteriosclerosis, Thrombosis and Vascular Biology 2013 Scientific Sessions, Lake Buena Vista, FL, April 2013.
Tuteja S, Dunbar R, Qu L, Li M, Mucksavage M, DerOhannessian S, Reilly M, Rader DJ: Perilipin 1 (PLIN1) genotype and not GPR109A associated with free fatty acid rebound following niacin administration [Poster Presentation] ATVB April 2013 Notes: Arteriosclerosis, Thrombosis and Vascular Biology 2013 Scientific Sessions, Lake Buena Vista, FL, April 2013.
deGoma,EM* and Dunbar, RL*, Jacoby, D, and French, B: Differences in absolute risk of cardiovascular events using risk-refinement tests: a systematic analysis of four cardiovascular risk equations. Atherosclerosis 227(1): 172-7, March 2013 Notes: *Co-first authors, equal contribution.
Maki KC, Orloff D, Nicholls S, Dunbar R, Roth E, Curcio DL, Johnson J, Kling DF, Davidson MH: A Highly Bioavailable Omega-3 Free-Fatty Acid Reduces Non-High Density Lipoprotein Cholesterol in High-Risk Patients Treated with a Statin and Residual Hypertriglyceridemia (ESPRIT Trial) [Poster Presentation] JACC 61(10): E1468, March 2013 Notes: 62nd Annual Scientific Session of the American College of Cardiology, San Fransisco, CA, March 2013.
deGoma,EM, Davis, MD, Dunbar, RL, Mohler, ER, III, Greenland, P, and French, B: Discordance between non-HDL-cholesterol and LDL-particle measurements: Results from the Multi-Ethnic Study of Atherosclerosis. Atherosclerosis March 2013.
Rader DJ, Dunbar RL, Maki KC, Jacobson TA, Kling D, Davidson MH : Apolipoprotein C-III is Significantly Reduced by Prescription Omega-3 Free Fatty Acids (Epanova) in Patients with Severe Hypertriglyceridemia and Changes Correlate with Increases in LDL-C: A Sub-analysis of the EVOLVE trial [Poster Presentation] Circulation 126(Supplement 21): A19030, November 2012 Notes: American Heart Association Scientific Sessions 2012, Los Angeles, CA, November, 2012.
Tuteja S, Bajaj G, Barrett JS, Dunbar RL, Reilly MP, Rader DJ: Pharmacokinetic and Pharmacodynamic Effects of Immediate Release Niacin [Poster Presentation] Pharmacotherapy 12(10), November 2012 Notes: 2012 American College of Clinical Pharmacology Annual Meeting, Hollywood, FL, October 2012.
Rader DJ, Dunbar RL, Maki KC, Jacobson TA, Kling D, Davidson MH: Apolipoprotein C-III is Significantly Reduced by Prescription Omega-3 Free Fatty Acids (Epanova) in Patients with Severe Hypertriglyceridemia and Changes Correlate with Increases in LDL-C: A Sub-analysis of the EVOLVE trial [Poster Presentation] Circulation 126(Supplement 21): A19030, November 2012 Notes: American Heart Association Scientific Sessions 2012, Los Angeles, CA, November 2012.
Qamar A, Usman H, Reilly M, Dunbar R, Rader D: Niacin Reverses Increased Plasma PCSK9 Induced by Statin and Fibrate Therapy: A Novel Mechanism for Further LDL Reduction [Poster Presentation] Circulation 126(Supplement 21): A13757, November 2012 Notes: American Heart Association Scientific Sessions 2012, Los Angeles, CA, November, 2012.
Usman HU, Qamar A, Gadi R, Lilly S, Goel H, Hampson J, Mucksavage M, Nathanson GA, Rader DJ, Dunbar RL: Extended-Release Niacin Acutely Suppresses Postprandial Triglyceridemia Am.J.Med. 125(10), October 2012.
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Last updated: 05/10/2013
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