faculty photo

Steven Eugene Raper

Associate Professor of Surgery
Department: Surgery
Contact information
HUP- 4th Floor Silverstein
3400 SPRUCE ST.
4283
Philadelphia, PA 19104
Email: seraper@mail.med.upenn.edu
Publications

Search PubMed for articles
Links
Search PubMed for articles
 Department of Surgery faculty webpage.
Education
M.D. (?)
University of Illinois, 1980.
Permanent link
 

Description of Research Expertise

From a clinical standpoint, I am interested in gastrointestinal surgical problems. In particular, my interests in complex pancreatic, liver and biliary tract disease mesh well with the mission of the University of Pennsylvania Medical center as a quaternary referral center. A second specific interest is metabolic surgery. The renaissance of interest in surgical procedures for the treatment of morbid obesity has created an opportunity for me to assist in the management of these complex patients. A second application is in the use of partial ileal bypass for the treatment of hypercholesterolemia. In both cases, surgery has proven capable of improving the metabolism of affected patients.

Selected Publications

McCullough BA, Yudkoff M, Batshaw ML, Wilson JM, Raper SE, Tuchman M: Genotype spectrum of ornithine transcarbamylase deficiency: correlation with the clinical and biochemical phenotype. Am J Med Genet 93(4): 313-9, August 14 2000.

 Chirmule N, Raper SE, Burkly L, Thomas D, Tazelaar J, Hughes JV, Wilson JM: Readministration of adenoviral vector in non-human primate lungs by blockade of CD-40-CD40L interactions. J Virol 74: 3345-3352, 2000.

 Raper SE: Acute pancreatitis secondary to dehydration: Case report and review of the literature. American Surgeon 65: 1084-1087, 1999.

 Nunes, FA, Furth EE, Wilson JM, Raper, SE: Gene transfer into the liver of non-human primates with E1-deleted recombinant adenoviral vectors: Safety of readministration. Human Gene Therapy 10: 2515-2526, 1999.

 Burke CV, Buettger CW, Davis EA, McClane SJ, Matschinsky FM, Raper SE: Cell biological assessment of human glucokinase mutants causing maturity onset diabetes of the young type 2 (MODY-2) or glucokinase-linked hyperinsulinemia. Biochemical Journal 342: 345-352, 1999.

 Chirmule N, Truneh A, Haecker SE, Tazelaar J, Gao G-P, Raper SE, Hughes JV, Wilson JM: Repeated administration of adenoviral vectors in lungs of human CD4 transgenic mice treated with a non-depleting CD4 antibody. J Immunol 163(1): 448-55, July 1 1999.

 DeMatteo RP, Yeh H, Friscia M, Capparelli D, Burke CV, Desai N, Chu G, Markmann JF, Raper SE, Barker CF: Cellular immunity delimits adenoviral gene therapy strategies for the treatment of neoplastic diseases. Ann Surg Onc Ann Surg Oncol 6(1): 88-94, Jan-Feb 1999.

 Hashimoto M, Kothary P, Raper SE: Phenobarbital in comparison with carbon tetrachloride and phenobarbital induced cirrhosis in rat liver regeneration. J Surg Res. 81: 164-169, 1998.

 Hashimoto M, Kothary P, Raper SE.: Treatment of cirrhotic rats with epidermal growth factor and insulin accelerates liver DNA synthesis after partial hepatectomy. J Gastrol Hepatol 13: 1259-1265, 1998.

 Ye X, Gao G-P, Pabin C, Raper SE, Wilson JM.: Evaluating the Potential of Germline Transmission after Intravenous Administration of Recombinant Adenovirus in the C3H Mouse. Human Gene Therapy 9(14): 2135-2142, 1998.
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Last updated: 10/06/2004
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