Selected Publications

Lee, C.S., Sund, N.J., Behr, R., Herrera, P.L. and Kaestner, K.H. : Foxa2 is required for the differentiation of pancreatic α-cells. Developmental Biology 278(2): 484-495, 2005.

Gupta, R.K., Vatamaniuk, M.Z., Lee, C.S., Flaschen, R.C., Fulmer, J.T., Matschinsky, F.M., Duncan, S.A., and Kaestner, K.H. : The MODY1 gene HNF-4α regulates selected genes involved in insulin secretion. Journal of Clinical Investigation 115: 1006-1015, 2005.

Lee, C.S., Friedman, J.R., Fulmer, J.T., and Kaestner, K.H. : The initiation of liver development is dependent of Foxa transcription factors. Nature 435: 944-947, 2005.

Lee, C.S., and Kaestner, K.H. : Differentiation of the gut endocrine cells. Best Practice and Research Clinical Endocrinology and Metabolism 18(4): 453-462, 2004.

Kaestner, K.H., Lee, C.S., Scearce, L.M., Brestelli, J.E., Arsenlis, A., Le, P.P., Lantz, K.A., Crabtree, J., Pizarro, A., Mazzarelli, J., Pinney, D., Fischer, S., Manduchi, E., Stoecker, Jr., C.J., Gradwohl, G., Clifton, S.W., Brown, J.R., Inoue, H., Cras-Meneur, C., and Permutt, M.A. : Transcriptional program of the endocrine pancreas in mice and humans. Diabetes 52: 1604-1610, 2003.

Scearce, L.M., Brestelli, J.E., McWeeney, S.K., Lee, C.S., Mazzarelli, J., Pinney, D.F., Pizarro, A., Stoeckert, C.J., Clifton, S.W., Permutt, M.A., Brown, J., Melton, D.A., Kaestner, K.H. : Functional genomics of the endocrine pancreas: the pancreas clone set and PancChip, new resources for diabetes research. Diabetes 51: 1997-2004, 2002.

Katz, J.P., Perreault, N., Goldstein, B., Lee, C.S., Labosky, P.A., Yang, V.W., Kaestner, K.H. : The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colonDevelopment. Development 129: 2619-2628, 2002.

Lee, C.S., Perreault, N., Brestelli, J.E., and Kaestner, K.H: Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity. Genes and Development 16: 1488-1497, 2002.

Lee, C.S., Sund, N.J., Vatamaniuk, M.Z., Matschinsky, F.M., Stoffers, D.A., and Kaestner, K.H. : Foxa2 controls Pdx1 gene expression in pancreatic β cells in vivo. Diabetes 51: 2546-2551, 2002.

Lee, C.S., and Fan, C.-M. : Embryonic expression patterns of the mouse and chick Gas1 genes. Mech Dev. 101: 293-297, 2001.