faculty photo

Kyoung Jae Won

Research Assistant Professor of Genetics
Department: Genetics

Contact information
Institute for Diabetes, Obesity and Metabolism
Perelman School of Medicine
12-111 Smilow Center for Translational Research
3400 Civic Center Blvd.
Philadelphia, PA 19104
Lab: 215-746-8424
Education:
B.Sc. (Electronics)
Chung-Ang University, Korea, 1996.
M.Sc. (Electronics )
Chung-Ang University, Korea, 1999.
Ph.D. (Electronics and Computer Science)
University of Southampton, UK, 2005.
Permanent link
 

Selected Publications

Harms Matthew J, Lim Hee-Woong, Ho Yugong, Shapira Suzanne N, Ishibashi Jeff, Rajakumari Sona, Steger David J, Lazar Mitchell A, Won Kyoung-Jae, Seale Patrick: PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program. Genes & development 29(3): 298-307, Feb 2015.

Choi Inchan, Kim Rinho, Lim Hee-Woong, Kaestner Klaus H, Won Kyoung-Jae: 5-hydroxymethylcytosine represses the activity of enhancers in embryonic stem cells: a new epigenetic signature for gene regulation. BMC genomics 15: 670, 2014.

Nguyen Nha, Vo An, Won Kyoung-Jae: A wavelet-based method to exploit epigenomic language in the regulatory region. Bioinformatics (Oxford, England) 30(7): 908-14, Apr 2014.

Step Sonia E, Lim Hee-Woong, Marinis Jill M, Prokesch Andreas, Steger David J, You Seo-Hee, Won Kyoung-Jae, Lazar Mitchell A: Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARĪ³-driven enhancers. Genes & development 28(9): 1018-28, May 2014.

Lake Robert J, Tsai Pei-Fang, Choi Inchan, Won Kyoung-Jae, Fan Hua-Ying: RBPJ, the Major Transcriptional Effector of Notch Signaling, Remains Associated with Chromatin throughout Mitosis, Suggesting a Role in Mitotic Bookmarking. PLoS genetics 10(3): e1004204, Mar 2014.

Won Kyoung-Jae, Zhang Xian, Wang Tao, Ding Bo, Raha Debasish, Snyder Michael, Ren Bing, Wang Wei: Comparative annotation of functional regions in the human genome using epigenomic data. Nucleic acids research 41(8): 4423-32, Apr 2013.

Won Kyoung-Jae, Ren Bing, Wang Wei: Genome-wide prediction of transcription factor binding sites using an integrated model. Genome biology 11(1): R7, 2010.

Xie Ruiyu, Everett Logan J, Lim Hee-Woong, Patel Nisha A, Schug Jonathan, Kroon Evert, Kelly Olivia G, Wang Allen, D'Amour Kevin A, Robins Allan J, Won Kyoung-Jae, Kaestner Klaus H, Sander Maike: Dynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells. Cell stem cell 12(2): 224-37, Feb 2013.

Won Kyoung-Jae, Xu Zheng, Zhang Xian, Whitaker John W, Shoemaker Robert, Ren Bing, Xu Yang, Wang Wei: Global identification of transcriptional regulators of pluripotency and differentiation in embryonic stem cells. Nucleic acids research 40(17): 8199-209, Sep 2012.

Won Kyoung-Jae, Chepelev Iouri, Ren Bing, Wang Wei: Prediction of regulatory elements in mammalian genomes using chromatin signatures. BMC bioinformatics 9: 547, 2008.

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Last updated: 03/24/2015
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