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Jorge Henao-Mejia

Assistant Professor of Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine

Contact information
The University of Pennsylvania
The Institute for Immunology
Biomedical Research Building II/III, Room 312
Philadelphia, PA 19104
Lab: 215-898-2212
Graduate Group Affiliations
Education:
M.D. (Medicine)
University of Antioquia, Colombia, 2005.
Ph.D. (Microbiology and Immunology)
Indiana University, 2009.
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Selected Publications

Henao-Mejia J*, Williams A*, Flavell RA*. Cold Spring Harb Protoc. (*Corresponding authors): Editing the Mouse Genome Using the CRISPR-Cas9 System Cold Spring Harb Protoc.(2), Feb 2016 Notes: Published under his first and last hyphenated name.

Henao-Mejia J*, Williams A*, Rongvaux A, Stein J, Hughes C, Flavell RA* (*Corresponding authors): Generation of genetically modified mice using the CRISPR/Cas9 genome editing system. Cold Spring Harb Protoc. (2), Feb 2016 Notes: Published under his first and last hyphenated name.

Krishnaswamy JK, Singh A, Gowthaman U, Wu R, Gorrepati P, Sales Nascimento M, Gallman A, Liu D, Rhebergen AM, Calabro S, Xu L, Ranney P, Srivastava A, Ranson M, Gorham JD, McCaw Z, Kleeberger SR, Heinz LX, Müller AC, Bennett KL, Superti-Furga G, Henao-Mejia J, Sutterwala FS, Williams A, Flavell RA, Eisenbarth SC: Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration. Proceedings of the National Academy of Sciences of the United States of America. Published under his first and last hyphenated name, 112(10): 3056-61, March 2015.

Henao-Mejia J.*, Elinav E*, Thaiss CA*, Flavell RA: Inflammasomes and Metabolic Disease. Annu Rev Physiol 76: 57-78, Nov 2014 Notes: Published under his first and last hyphenated name.

Wlodarska M, Nowarski R, Thaiss CA, Henao-Mejia J, Zhang JP, Frankel G, Hao L, Philbrick WM, Elinav E, Finlay BB, Flavell RA: NLRP6 inflammasome regulates the intestinal host-microbial interface by orchestrating globlet cell-mediated mucus secretion. Cell 156(5): 1045-1059, February 2014 Notes: Published under his first and last hyphenated name.

Hacisuleyman E., Goff LA, Trapnell C, Sauvageau DC, Hendrickson DR, Kelley P, McClanahan A, Henao-Mejia J, Sun L, Engreitz J, Guttman M, Lander ES, Flavell RA, Lodish HF, Raj A, Rinn JL: Trans-chromosomal and nuclear matrix interactions require a lincRNA that escapes X chromosome inactivation. Nat Struct Mol Biol 21(2): 198-206, February 2014 Notes: Published under his first and last hyphenated name.

Henao-Mejia J,* Elinav E*, Thaiss CA, Licona-Limon P, Flavell RA: Role of the intestinal microbiome in liver disease. J Autoimmun 46: 66-73, October 2013 Notes: No issue no. Published under his first and last hyphenated name.

Licona-Limon P, Henao-Mejia J, Temann AU, Gagliani N, Licona-Limon I, Ishigame H, Hao L, Herbert DR, Flavell RA : Th9 cells drive host immunity against gastrointestinal worm infection. Immunity. Published under his first and last hyphenated name, 39(4): 744-757, October 2013.

Williams A.*, Henao-Mejia J*, Harman CD, Flavell RA: miR-181 and metabolic regulation in the immune system. Cold Spring Harb Symp Quant Biol 78: 223-230, October 2013 Notes: *These authors contributed equally to this work. Published under his first and last hyphenated name.

Jin C,* Henao-Mejia J,* Flavell RA: Innate immune receptors: Key regulators of metabolic diseases progression. Cell Metabolism 17(6): 873-882, June 2013 Notes: *These authors contributed equally to this work. Published under his first and last hyphenated name

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Last updated: 07/12/2016
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