faculty photo

Jorge Henao-Mejia

Assistant Professor of Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine

Contact information
The University of Pennsylvania
The Institute for Immunology
Biomedical Research Building II/III, Room 321
Philadelphia, PA 19104
Lab: 215-898-2212
Graduate Group Affiliations
M.D. (Medicine)
University of Antioquia, Colombia, 2005.
Ph.D. (Microbiology and Immunology)
Indiana University, 2009.
Permanent link

Selected Publications

Krishnaswamy JK, Singh A, Gowthaman U, Wu R, Gorrepati P, Sales Nascimento M, Gallman A, Liu D, Rhebergen AM, Calabro S, Xu L, Ranney P, Srivastava A, Ranson M, Gorham JD, McCaw Z, Kleeberger SR, Heinz LX, Müller AC, Bennett KL, Superti-Furga G, Henao-Mejia J, Sutterwala FS, Williams A, Flavell RA, Eisenbarth SC: Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration. Procedures of the National Academy of Sciences of the United States of America 112(10): 3056-61, March 2015.

Adam Williams*, Jorge Henao-Mejia*, Richard A. Flavell* * Corrsponding authors and equal contribution: The generation of genetically modified mice using the CRISPR/Cas9 genome editing system Cold Spring Harbor Protocols Page: In press, 2015.

Jorge Henao-Mejia1*, Adam Williams*, Anthony Rongvaux, Judith Stein, Cynthia Hughes, Richard A. Flavell* *Corresponding authors and equal contribution: Protocol for the generation of genetically modified mice using the CRISPR/Cas9 genome editing system Cold Spring Harbor Protocols Page: In Press, 2015.

Henao-Mejia J.*, E. Elinav*, C.A. Thaiss*, R.A. Flavell: Inflammasomes and metabolic disease. Annu Rev Physiol 76: 57-78, Nov 2014.

Wlodarska M., R. Nowarski, C.A. Thaiss, J. Henao-Mejia, J.P. Zhang, G. Frankel, L. Hao, W.M. Philbrick, E. Elinav, B.B. Finlay, R.A. Flavell: NLRP6 inflammasome regulates the intestinal host-microbial interface by orchestrating globlet cell-mediated mucus secretion. Cell 156(5): 1045-1059, 2014.

Hacisuleyman E., L.A. Goff, C. Trapnell, M. Sauvageau, D.G. Hendrickson, D.R Kelley, P. McClanahan, A. Williams, J. Henao-Mejia, L. Sun, J. Engreitz, M. Guttman, E.S. Lander, R.A. Flavell, H.F. Lodish, A. Raj, J.L. Rinn: Trans-chromosomal and nuclear matrix interactions require a lincRNA that escapes X chromosome inactivation. Nat Struct Mol Biol. 21: 198-206, 2014.

Henao-Mejia, J.*, E. Elinav*, C.A Thaiss, Paula Licona-Limon, R.A. Flavell: Role of the intestinal microbiome in liver disease. J Autoimmun 46: 66-73, October 2013.

Licona-Limon P., J. Henao-Mejia, A.U. Temann, N. Gagliani, I. Licona-Limon, H. Ishigame, L. Hao, D.R. Herbert, R.A. Flavell. : Th9 cells drive host immunity against gastrointestinal worm infection. Immunity 39(4): 744-757, October 2013.

Williams A.*, J. Henao-Mejia*, C.D. Harman, R.A. Flavell: miR-181 and metabolic regulation in the immune system. Cold Spring Harb Symp Quant Biol. 78: 223-230, October 2013 Notes: *These authors contributed equally to this work.

C. Jin* , J. Henao-Mejia* and R.A. Flavell: Innate immune receptors: Key regulators of metabolic diseases progression. Cell Metabolism 17(6): 873-882, June 2013 Notes: *These authors contributed equally to this work.

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Last updated: 11/19/2015
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