John R. Stanley, M.D.
John R. Stanley, M.D.
Professor of Dermatology
Department: Dermatology
Contact information
University of Pennsylvania School of Medicine
Department of Dermatology
415 Curie Boulevard, 211 Clinical Research Building
Philadelphia, PA 19104
Department of Dermatology
415 Curie Boulevard, 211 Clinical Research Building
Philadelphia, PA 19104
Office: 215-898-3240
Fax: 215-573-2033
Fax: 215-573-2033
Email:
JRSTAN@MAIL.MED.UPENN.EDU
JRSTAN@MAIL.MED.UPENN.EDU
Education:
B.A. (Physics)
Cornell University, 1970.
M.D.
Harvard Medical School, 1974.
Permanent linkB.A. (Physics)
Cornell University, 1970.
M.D.
Harvard Medical School, 1974.
Selected Publications
Yamagami J, Payne AS, Kacir S, Ishii K, Siegel DL, Stanley JR: Homologous regions of heavy chain complementarity determining region 3 (H-CDR#) of pemphigus antibodies cause pathogenicity. J Clin Invest 120: 4111-4117, 2010.Yamagami J, Kacir S, Ishii K, Payne AS, Siegel DL, Stanley JR: Antibodies to the desmoglein 1 precursor proprotein but not to the mature cell surface protein cloned from individuals without pemphigus. J Immunol. PMCID: PMC2766247 (eds.). 183: 5615-5621, 2009 Notes: In press.
Yokouchi M, Saleh MA, Kuroda K, Hachiya T, Stanley JR, Amagai M, Ishii K: Pathogenic epitopes of autoantibodies in pemphigus reside in the amino-terminal adhesive region of desmogleins which are unmasked by proteolytic processing of prosequence. J Invest Dermatol. PMCID: PMC2829729 (eds.). 129: 2156-2166, 2009.
Yamagami J, Kacir S, Ishii K, Payne AS, Siegel DL, Stanley JR: Antibodies to the desmoglein 1 precursor proprotein but not to the mature cell surface protein cloned from individuals without pemphigus. J Immunol. PMCID: PMC2766247 (eds.). 183: 5615-5621, 2009.
Stanley JR, Ishii K, Siegel DL, Payne AS: Update on the cloning of monoclonal anti-desmoglein antibodies from human pemphigus patients: implications for targeted therapy. Veterinary Dermatology. PMCID: PMC2829729 (eds.). 20: 327-330, 2009.
Stanley JR, Amagai M: Autoimmune bullous diseases: historical perspectives. J Invest Dermatol. (electronic publication on Nature Publishing JID website) (eds.). 128: E16-E18, 2008.
Ishii K, Lin C, Siegel DL, Stanley JR: Isolation of pathogenic monoclonal anti-desmoglein 1 human antibodies by phage display of pemphigus foliaceus autoantibodies. J Invest Dermatol. PMCID: PMC2597791 (eds.). 128: 939-948, 2008.
Payne AS, Siegel DL, Stanley JR: Targeting pemphigus autoantibodies by their heavy chain variable region genes. J Invest Dermatol 127: 1681-1691, 2007.
Heng A, Nwaneshiudu A, Hashimoto T, Amagai M, Stanley JR: Intraepidermal neutrophilic IgA/IgG anti-desmocollin 1 pemphigus. Br J Dermatol 154: 1018-1019, 2006.
Stanley JR, Amagai M: Pemphigus, bullous impetigo, and staphylococcal scalded skin syndrome. N Engl J Med 355: 1800-1810, 2006.