Democracy, Governance and Curbing Corruption in Sub-Saharan Africa

Location: Cheyney University of Pennsylvania

An international conference organized by the Master of Public Administration Program, in collaboration with The African & Caribbean Business Council.

While other regions of the world are making strides in improving the living standards of their citizens, Sub-Saharan Africa (SSA) is still trapped in poverty with more than 40% of its 600 million people living below the internationally recognised absolute poverty level of US$ 1 per day. Several reports highlight corruption as one of the institutional and systemic problems responsible for keeping million of Africans under absolute poverty. In fact, the 2008 Transparency International report demonstrates a direct link between corruption and failure of societal institutions to effectively achieve the Millennium Development Goals (MDGs) in SSA. It is a serious concern that the goals of halving poverty in SSA by the year 2015 from the level of 1990 will not be met.

For additional information including call for papers, registration and lodging, please visit the conference website at: http://www.cheyney.edu/international-anticorruption/index.cfm

Speaker: Darrell Kotton, M.D.  Affiliation: Boston University Center for Regenerative Medicine

PGG 29th ANNUAL STUDENT SYMPOSIUM

NATIONAL CONSTITUTION CENTER, 525 ARCH STREET

OCTOBER 25, 2012 

Marie E. Burns, Ph.D.
Professor Department of Ophthalmology & Vision Science University of California, Davis

Physiology Conference Room B400 Richards Building

Title:  Feedback required: Stability and reproducibility of single photon responses of retinal rods

4:00PM - 5:00PM

Emeritus Professor

Department of Physiology

University of Pennsylvania

Physiology Conference Room B400 Richards Building

4:00PM-5:00PM

Title:  Gating and selectivity in K+ channels

For more information call: (215) 898-8725

Assistant Professor

Instituto de Neurobiologia

Universidad de Puerto Rico

Title:  Fine tuning excitability through RNA editing in cephalopods

Physiology Conference Room

B404 Richards Building 4PM-5PM

Location: Class of '62, JMB

ADvisor: Dr. Gregory Bashaw

• How psychological type preferences affect us in conflict
• A unique three-stage model for managing conflict through type
• Ways to best approach, communicate during, and resolve conflict situations

• Hiring/Posting
• Conflict of Interest
• Paid Time Off
• Terminations

Attendees: CDA, Practice Manager/Coordinator of each location, Clinical RN Manager

Call in #: 800-314-2582

Part of the CPHI's 2012/2013 Seminar Series Proof or Consequences: Evidence and Controversy in Public Health

Paul A. Offit, MD is the Chief of the Division of Infectious Diseases and the Director of the Vaccine Education Center at the Children’s Hospital of Philadelphia.He is also the author of five medical narratives: The Cutter Incident: How America’s First Polio Vaccine Led to Today’s Growing Vaccine Crisis (Yale University Press, 2005), Vaccinated: One Man’s Quest to Defeat the World’s Deadliest Diseases (HarperCollins, 2007), for which he won an award from the American Medical Writers Association, Autism’s False Prophets: Bad Science, Risky Medicine, and the Search for a Cure (Columbia University Press, 2008), Deadly Choices: How the Anti-Vaccine Movement Threatens Us All (Basic Books, 2011), and Killing Us Softly: The Sense and Nonsense of Alternative Medicine (HarperCollins, 2013).

RSVP: https://docs.google.com/spreadsheet/viewform?formkey=dHJLMDJPUE1yNEtTeGtLMUFhVUJibXc6MQ

The Institute for Diabetes, Obesity, and Metabolism; the Division of Endocrinology, Diabetes, and Metabolism; and the Diabetes Research Center

Combined Fall 2012 Seminar Series presents:

 Joseph A. Baur, Ph.D
University of Pennsylvania

Professor of Immunology and Pathogenesis

University of California, Berkeley 

“Role Of Natural Killer Cell Receptors In Cancer Surveillance And Inflammatory Disease”

Austrian Auditorium

Assistant Professor

Division of Biological Sciences

University of California San Diego

“Molecular Determinants of Viral Control versus Persistence”

Austrian Auditorium

Associate Professor, Medicine

Immunology & Rheumatology

Stanford School of Medicine

“Dissecting Autoimmunity Using Multiplexed Assays”

Austrian Auditorium

Professor,

Blood Cell Development and Cancer Keystone Program

Immune Cell Development and Host Defense Program

Fox Chase Cancer Center

"Role of ribosomal protein paralogs in hematopoietic development and disease"

Austrian Auditorium

Robert T. Haslam Professor of Chemical Engineering
Department of Biological Engineering
Massachusetts Institute of Technology

"How to Hit HIV Where It Hurts."

Austrian Auditorium

The Center for Mental Health Policy and Services Research
The Neuroscience of Behavior Initiative and
The Leonard Davis Institute of Health Economics

Present

Marc S. Atkins, Ph.D.
Professor of Psychiatry and Psychology, University of Illinois at Chicago

New Models for Children’s Mental Health Services in Urban Communities: Drilling Deeper in Urban Schools

Monday, October 1st, 2012
Time: 1:30pm-3:00pm
Location: Steinberg-Dietrich Hall | Room 215 | 3620 Locust Walk

Dr. Atkins is Professor of Psychiatry and Psychology at the University of Illinois at Chicago where he holds appointments in the Department of Psychiatry and the Institute for Juvenile Research.  He is a leading researcher in the development of effective mental health services for children and families living in low-income communities.  He will present a mental health service model that identifies and leverages indigenous resources within schools and communities to change the social context of schooling for youth in urban poverty, and promote opportunities for positive mental health and improved academic outcomes for children.

RSVP: mdowney@upenn.edu

Leibniz Institute for Age Research, Germany

"Molecular mechanisms of stem cell aging and transformation"

Austrian Auditorium

Mount Sinai School of Medicine

Studying virus/host interactions through the exploitation of miRNAs

Austrian Auditorium

Sanford-Burnham Medical Research Institute

Viral rewiring of cytokine communication networks

Austrian Auditorium

Yale School of Medicine

Exploiting virus-host interactions for new HBV immunotherapies

Austrian Auditorium 

University of Wisconsin, Madison

Viral mini-organelles for genomic RNA replication: Structure, assembly & function

Austrian Auditorium

University of Wisconsin, Madison

Hepatitis B virus: The gymnastics of genome replication

Austrian Auditorium

"Chemotherapy induced peripheral neuropathy in non-metastatic breast cancer: Patient experience and clinical impact"

Rebecca Speck
PhD Candidate
Division of Epidemiology
Department of Biostatistics and Epidemiology

Dissertation Advisor: Angela DeMichele, MD, MSCE
Committee Chair: Mary Sammel, ScD

Abstract: Chemotherapy induced peripheral neuropathy (CIPN) is an adverse effect of multiple chemotherapeutic agents, including taxane-based chemotherapy, the most frequently used therapy for treating breast cancer – the most common cancer among women. CIPN symptoms are a serious burden for patients – affecting quality of life, threatening safety, and preventing delivery of maximally effective treatment. Few prevention options have been tested, and no available symptomatic therapies have demonstrated effectiveness. As a result, patients are forced to cope with symptoms, and oncologists must decide whether to modify treatment schedule, dose, and completion. Using a purposive sample of 25 breast cancer patients treated with docetaxel or paclitaxel, half with and half without CIPN, we conducted semi-structured interviews to explore the self-management strategies utilized to cope with the affect of CIPN symptoms, and to discriminate the CIPN experience from other toxicities. We also conducted a retrospective cohort study of 488 women treated with docetaxel or paclitaxel for non-metastatic breast cancer to measure the incidence of treatment modification (TM) events attributed to CIPN (CIPN-TM), and assess whether body mass index (BMI) and body surface area (BSA) were risk factors. Through qualitative data analysis we found that CIPN affected routine activities, functions, and behaviors in the areas of domestic, work, and social/leisure life. Multiple self-management and coping strategies to minimize the impact of CIPN symptoms were reported; the focus was on movement to reduce symptoms, attitude awareness, logistics to simplify demands, and environmental change. We also found that taste alteration was a commonly experienced side effect, regardless of CIPN status. Similarly to CIPN, taste alteration affected breast cancer patients' lives, and patients developed management strategies to deal with the effect. In the retrospective cohort study 50 (10.2%) women had a TM-CIPN, (2.4% with docetaxel and 16.1% with paclitaxel, p<0.001). BMI and BSA were not independently associated with the risk of TM-CIPN, suggesting that CIPN itself is not leading to inferior treatment delivery in obese breast cancer patients. Assessment of the effectiveness of reported self-management strategies is a logical target of future research. Other explanations for the disparity in survival outcomes among obese patients deserve investigation. 

Associate Professor

Pathology and Laboratory Medicine

Reunion Hall, JMB

Associate Professor

Microbiology

"Mechanisms controlling CD8 T cell activation and longevity"

Reunion Hall, JMB

Associate Professor

Pathology and Laboratory Medicine

 Shirley Zhang:
Homing of T cell progenitors to the thymus is compromised after transplant and in acute inflammation

Christelle Harly:
Distinct roles for transcription factor TCF-1 in early T cell progenitors and mature T cells

Reunion Hall, JMB

Professor

 Pathology and Laboratory Medicine

**Note location change for this seminar to Class of '62, JMB***

The Grand Hotel

1045 County Highway 604, Cape May, NJ 08204

S. Lawrence Zipursky, Ph.D.
Professor, Department of Biological Chemistry

Investigator, Howard Hughes Medical Institute

David Geffen School of Medicine, UCLA

http://www.biolchem.ucla.edu/labs/zipursky/l3.html

http://biochemweb.slu.edu/people/faculty/dorsett.shtml

NIH

"Therapeutic Strategies in Lymphoma Inspired by Functional and Structural Genomics"

Grossman Auditorium, The Wistar Institute

3601 Spruce Street

Speaker 1: Ben Voight

Speaker 2: Struan Grant

Speaker 3: Adam Naj

Host: Sira Sriswasdi

Speaker 1: Brian Gregory

Speaker 2: Li-San Wang

Speaker 3: Ramana Davuluri

Student host: Nick Lahens

Speaker 1: John Murray

Speaker 2: Ben Garcia

Speaker 3: Klaus Kaestner

Student host: Gabe Otte

Speaker 1: Arjun Raj

Speaker 2: David Issadore

Student host: Paul Ryvkin

Speaker 1: Rui Feng

Speaker 2: Sharon Diskin

Speaker 3: Nancy Zhang

Student Host: Joe Glessner

Location: TRC 1-149AB

Advisor: Dr. Jeffrey Golden

Location: JMB, Class of '62

Advisor: Dr. Celeste Simon

Thomas Jefferson University

Department of Cancer Biology

Kimmel Cancer Center

 Jefferson Medical College Professor

“Reprogramming cellular metabolism in cancer:  Essential role of the MYC oncoprotein”

Abramson Building, Ground Floor
123 A/B Conference Rooms, Lunch Provided

10am-2pm in the Translational Research Building Commons Lobby

Paul W. Sternberg, Ph.D.

Thomas Hunt Morgan Professor of Biology

Investigator, Howard Hughes Medical Institute

California Institute of Technology

http://wormlab.caltech.edu/members/paul.html

Dr. Garbine Riley is a dermatologist from Guatemala coming to give the Grand Rounds lecture on Oct 4. She is an expert in Leprosy and will be speaking on the topic. Anyone from Global Health/med school is invited to hear her lecture from 11AM-noon in TRC auditorium (attached to PCAM). She also has time in the afternoon to meet with anyone who may be interested in leprosy or global health in Guatemala.

 Speaker:  Kenneth Hugh Mayer, MD

Time: Thursday October 4th, 2012 at Noon

Topic:  Pre-Exposure Prophylaxis

Speaker: Elmi Muller, MD

Time: Thursday October 11th, 2012 at Noon

Topic: TBD

Speaker: Karam Mounzer, MD

Time: Thursday October 18th, 2012 at Noon

Topic: Real Cases from the Hospital at the University of Pennsylvania

Tom Hope, M.D. - "Using Cell Biology Approaches to Understand HIV Transmission"

October 26, 2012

Richard L. Doty, Ph.D.
Otorhinolaryngology
“Neurodegenerative Diseases & Chemosensory Dysfunction: Is There A Common Casual Denominator”

October 26, 2012

Richard L. Doty, Ph.D.
Otorhinolaryngology
“Neurodegenerative Diseases & Chemosensory Dysfunction: Is There A Common Casual Denominator” 

Penn Medicine

Neuroscience of Behavior Initiative

Invites:

Associate Professor, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine

Associate Professor, Department of Mental Health

Associate Professor, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health

Presents:

"The Search for Susceptibility Genes in Bipolar Disorder"

Wednesday, October 24^th, 2012 at 1:45pm

Barchi Library, Room 140 John Morgan Building

Led by visiting Penn medical students.

All are welcome to attend.

Next Pre-departure Orientation for Penn Travelers: October 11, 2012

The next pre-departure orientation for Penn travelers headed to Botswana will take place Thursday, October 11, from 4-6 PM in the 5th Floor Conference Room of the Johnson Pavilion at 3610 Hamilton Walk on Penn's Campus. We will give an overview of Botswana history, culture, and the work of the Partnership, in addition to providing traveler tips (e.g., currency, booking flights). All are welcome to attend. Bring your questions!

Dr. Mike Reid will visit Good Hope on October 10th 

This month's outreach lecture: Respiratory distress and CHF

Dr. Mike Reid will be visiting Thamaga on October 4rth 

This month's outreach lecture: Respiratory distress and CHF

The outreach lecture this month is on 'Respiratory distress and CHF.' 

As ever if you have any HIV/internal medicine clinical questions, please free to contact Dr Mike Reid (+267 724 78 777) or Dr Miriam Haverkamp (+269 765 16 520).   

The outreach lecture this month is on 'Respiratory distress and CHF.' 

As ever if you have any HIV/internal medicine clinical questions, please free to contact Dr Mike Reid (+267 724 78 777) or Dr Miriam Haverkamp (+269 765 16 520).   

The outreach lecture this month is on 'Respiratory distress and CHF.' 

The outreach lecture this month is on 'Respiratory distress and CHF.' 

The outreach lecture this month is on 'Respiratory distress and CHF.' 

Assistant Professor of Pathobiology
School of Veterinary Medicine

"Regulation of Cell Death and Inflammation During Bacterial Infection"

132 Hill Pavilion

The newly established Basser Research Center for BRCA 1 and 2 hosts monthly research conferences, which include presentations by two researchers and discussion over lunch.  Lunch will be provided.

       Andrea Facciabene, PhD, on Development of vaccine targeting the tumor vasculature for the prevention of BRCA-deficient tumors

       Susan Domchek, MD, on Cancer Risk Evaluation Program: current and future biobank

These conferences are open to all, and no registration is necessary. 

“Lessons Learned Translating Research into Practice.” 

Ruth McCorkle, PhD, RN, FAAN

Florence Schorske Wald Professor of Nursing and Professor of Epidemiology

Yale School of Public Health

Reception to follow.

"Yoga Research: Past, Present and Future.” 

Sat Bir Singh Kalsa, PhD

Assistant Professor of Medicine, Harvard Medical School

RSVP to Sandy Slaughter, sandra.slaughter@uphs.upenn.edu.

Investigator, Howard Hughes Medical Institute

DEPARTMENT OF RADIOLOGY
Division of Nuclear Medicine

 Dr. Robert Mach
Washington University
Director of the Cyclotron Facilities
and Radiological Chemistry Lab

"Imaging Cancer Cell Proliferation,
Quiescence, and Apoptosis with PET"

Thursday - October 25, 2012
11:00 a.m. – 12:00 (Noon)
Department of Radiology – Nuclear Medicine Division
Donner Basement – Donner Auditorium

DEPARTMENTS OF
Neuropsychiatry, Psychiatry, and Radiology
Neuroscience of Behavior Initiative

Dr. Robert Mach
Washington University
Director of the Cyclotron Facilities
and Radiological Chemistry Lab

"Differential Distribution of Dopamine
D2 and D3 Receptors in Brain Measured
with PET and Autoradiography"

Friday - October 26, 2012
1:00 p.m. – 2:45 p.m.
Reunion Hall – John Morgan Building - Ground Floor

Penn Medicine

Neuroscience of Behavior Initiative

Invites:

Professor, Department of Psychiatry and Behavioral Sciences

Professor, Hematology and Medical Oncology

Emory University School of Medicine

Presents:

"Inflammation and Treatment Resistance in Major Depression: A Perfect Storm"

Friday, November 2^nd, 2012 at 12:00pm

Barchi Library, Room 140 John Morgan Building

"Perspectives: Healthcare in Africa" will take place on Thursday, October 11th at 5PM in JMHH 260 (Huntsman Hall). The speaker panel will feature:

Dr. Harvey M. Friedman, Perelman School of Medicine
Dr. Friedman is the director of the Botswana-UPenn Partnership at the medical school, as well as the Chief of the Infectious Diseases Division.

Dr. Timothy Rebbeck, Perelman School of Medicine
Dr. Timothy Rebbeck of the Abramson Cancer Center has research interests related to prostate cancer in West Africa. He has worked with urology and oncology collaborators in Dakar, Senegal, and Accra, Ghana, and is currently working on a research project on the genetics of prostate cancer in Dakar.

Megan Doherty
Megan works in the Center of Public Health Initiatives at Penn, and teaches on water and sanitation projects in Cameroon, as well as community health in Ghana. Megan is also a returned volunteer from the Peace Corps, where she worked in the health sector in Mali.

Pamela Hoto, SAS ’16
Pamela was born and raised in Zimbabwe and will be discussing her personal firsthand experiences with the healthcare she received there.

Elizabeth Mensah, Wharton ‘13
Elizabeth will be writing her senior thesis on healthcare management in Africa and will discuss her current research progress. 

 The event's purpose is to educate Penn students on campus about healthcare systems in Africa comparatively to the United States and the rest of the world.

World Food Day 2012

World Food Day is Oct. 16, but we'll be getting together on Sunday Oct. 14, 2012 from 2-5 p.m. at Hopkinson House Solarium 604 S Washington Square, 31st floor, Philadelphia, PA to observe it.

Speakers:

Dr. Alan Kelly

(UPenn)

"Urban food security in the   
 developing world"

Bob Pierson

(Philadelphia Common Market)

"Local Food Cooperatives  

and Partnerships"

Dr. Alison Buttenheim 

(UPenn)

"Farmers' Markets Expanding

Access to Healthy Foods"

Admission: Free.

Light fare provided.  Cash bar.

The first hour, Sir Richard Feachem will speak to the historical patterns of malaria control, the outcomes of accelerated global efforts in the past decade, outstanding challenges, and policy priorities for the next Administration and Congress. The second hour will be moderated discussion with Sir Richard Feachem and Rear Admiral Tim Ziemer on the U.S. anti-malaria agenda moving forward.

** This event will be webcast live at: www.SmartGlobalHealth.org/Live**

The first hour, Sir Richard Feachem will speak to the historical patterns of malaria control, the outcomes of accelerated global efforts in the past decade, outstanding challenges, and policy priorities for the next Administration and Congress. The second hour will be a moderated discussion with Sir Richard Feachem and Rear Admiral Tim Ziemer on the U.S. anti-malaria agenda moving forward.

** This event will be webcast live at: www.SmartGlobalHealth.org/Live**

Water, Sanitation, and Hygiene (WASH) Interventions for Eliminating Cholera on Hispaniola

October 19, 2012, will mark the two-year anniversary of the cholera outbreak on the island of Hispaniola. Over the past two years a range of multilateral organizations, government agencies, and non-governmental program implementers, have been working to assist the Governments of Haiti and the Dominican Republic in controlling the spread of cholera – emphasizing the importance of water, sanitation, and hygiene (WASH) interventions. To acknowledge the island’s two-year effort to control the spread of cholera and to advance action in support of the Regional Coalition on Water and Sanitation for the Elimination of Cholera in the Island of Hispaniola, CSIS and PAHO will convene two expert-led panel discussions that will focus on the challenges posed by the outbreak, describe the opportunities presented by regional collaboration on WASH activities, and identify opportunities for greater engagement on cholera elimination by the non-government sector.

Agenda

Welcome and Introductions
Katherine Bliss, CSIS

 Panel One: High Level Engagement with the Coalition
Jon Andrus, Pan American Health Organization, moderator
Jordan Tappero – U.S. Centers for Disease Control and Prevention
Kent Hill, World Vision and United States Water Partnership (invited)
Representative, Government of Haiti (invited)
Representative, World Bank (invited)

Panel Two: On the Ground Support for WASH and Cholera Activities
Katherine Bliss, CSIS, moderator
Louise Ivers, Partners in Health
Sy Rotter, Veolia Environment Foundation
Loune Viaud, Zanmi Lasante

** This event will be webcast live at: www.SmartGlobalHealth.org/Live**

Water, Sanitation, and Hygiene (WASH) Interventions for Eliminating Cholera on Hispaniola

October 19, 2012, will mark the two-year anniversary of the cholera outbreak on the island of Hispaniola. Over the past two years a range of multilateral organizations, government agencies, and non-governmental program implementers, have been working to assist the Governments of Haiti and the Dominican Republic in controlling the spread of cholera – emphasizing the importance of water, sanitation, and hygiene (WASH) interventions. To acknowledge the island’s two-year effort to control the spread of cholera and to advance action in support of the Regional Coalition on Water and Sanitation for the Elimination of Cholera in the Island of Hispaniola, CSIS and PAHO will convene two expert-led panel discussions that will focus on the challenges posed by the outbreak, describe the opportunities presented by regional collaboration on WASH activities, and identify opportunities for greater engagement on cholera elimination by the non-government sector.

Agenda

Welcome and Introductions
Katherine Bliss, CSIS

 Panel One: High Level Engagement with the Coalition
Jon Andrus, Pan American Health Organization, moderator
Jordan Tappero – U.S. Centers for Disease Control and Prevention
Kent Hill, World Vision and United States Water Partnership (invited)
Representative, Government of Haiti (invited)
Representative, World Bank (invited)

Panel Two: On the Ground Support for WASH and Cholera Activities
Katherine Bliss, CSIS, moderator
Louise Ivers, Partners in Health
Sy Rotter, Veolia Environment Foundation
Loune Viaud, Zanmi Lasante

** This event will be webcast live at: www.SmartGlobalHealth.org/Live**

Webinar Thursday: Insider tips to land your global health internship!

Don't forget to register for our upcoming webinar to learn more about starting your career in global health. Three former GHFP-II interns, and two GHFP-II staff members will be on hand to discuss paths into global health, the experience of a USAID intern, and to directly answer your questions! It is our mission to bring a wider audience into conversation with global health, and to help the body of global health professionals reflect the diversity of the American people.

This webinar comes at no cost to you, and is available wherever internet access is served. We look forward to seeing you Thursday!

GHFP-II Webinar

How to land your Global Health internship - Tips from recruiters and interns!

Date and Time

Thursday October 11, 2012  |  2-3:30 pm EST  |  11 am - 12:30 pm PST

Click here for registration. 

Time is limited!

Wistar Professor, Department of Pharmacology

 "Stromal cells and extracelluar matrix in homeostasis and disease"

132 Hill Pavilion

October 15, 2012 at 2pm

CRB Austrian Auditorium

Dr. Marileen Dogterom

“Deciphering microtubule-based positioning strategies in vitro”

Developing a Long-Term Academic/Community Partnership to Address Latino Health Disparities

Matt O’Brien, MD, MSc

Assistant Professor of Medicine and Public Health, Temple University

Medical Director, Puentes de Salud

Wednesday, October 24^th, 2012

1:00pm – 2:00pm

BRB 253

Join Dr. O’Brien as he talks about his experiences in establishing a long-term academic/community partnership, which is called Puentes de Salud.  Puentes de Salud (“Bridges of Health”) is an immigrant health center that provides primary care services and a wide range of community-based educational programs to a rapidly growing Latino immigrant community in Philadelphia.  Dr. O’Brien will present on his research that is conducted through this academic/community partnership and in the South Philadelphia Latino community.  Much of his research focuses on obesity and nutrition, diabetes prevention, cancer prevention, and health literacy in Latinos.

Dr. O’Brien is a general internist who completed medical school at Brown University in 2004, residency in Internal Medicine at the University of Pennsylvania in 2007, and the Robert Wood Johnson Clinical Scholars Program in 2010.  Dr. O’Brien is currently an Assistant Professor of Medicine and Public Health at Temple University, as well as a founder and Medical Director of Puentes de Salud.

The Endocrinology Grand Rounds Series presents:

Diana Stanescu, MD and Anthony Gannon, MD - CHOP Fellows

Topic: "Neonatal Diabetes - A Case of Growing Concern"

Date: Wednesday, October 17,  2012

Time: 12:00 noon - 1:00 pm

Location: 12th Floor - TRC - Translational Research Center 12-146

**************************************************************

Educational Objectives

After completing this activity, participants should be able to:

• Apply the latest clinical guidelines in the management of endocrine diseases
• Evaluate and efficacy of therapeutic options in endocrine disorders
• Describe the results of translational research as it pertains to endocrine diseases

Accreditation

The Perelman School of Medicine at the University of Pennsylvania is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education to physicians

Designation of Credit

The Perelman School of Medicine at the University of Pennsylvania designates this live activity for a maximum of 1 AMA PRA Category 1 Credit(s)TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The Endocrinology Grand Rounds Series presents:

Douglas L. Fraker, MD - Chief, Division of Endocrine and Oncologic Surgery

Topic: "Parathyroid"

Date: Wednesday, October 24,  2012

Time: 12:00 noon - 1:00 pm

Location: 12th Floor - TRC - Translational Research Center 12-146

**************************************************************

Educational Objectives

After completing this activity, participants should be able to:

• Apply the latest clinical guidelines in the management of endocrine diseases
• Evaluate and efficacy of therapeutic options in endocrine disorders
• Describe the results of translational research as it pertains to endocrine diseases

Accreditation

The Perelman School of Medicine at the University of Pennsylvania is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education to physicians

Designation of Credit

The Perelman School of Medicine at the University of Pennsylvania designates this live activity for a maximum of 1 AMA PRA Category 1 Credit(s)TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

"Statistical methods for non-ignorable missing data with applications to quality-of-life data"

Kaijun Liao
PhD Candidate
Division of Biostatistics
Department of Biostatistics and Epidemiology

Dissertation Advisor: Andrea B. Troxel, ScD
Committee Chair: Mary E. Putt, PhD, ScD
Committee Members: Katrina Armstrong, MD, MSCE, Benjamin C. French, PhD

Abstract: In chronic disease studies, researchers increasingly use more and more survey studies, and design medical studies to better understand the relationships of patients, physicians, their health care system utilization, and their decision making process in disease prevention and management. Longitudinal data is widely used to capture disease progression or trends occurring over time. Each subject is observed as time progresses. A common problem is that repeated measurements are not fully observed due to missing responses or loss to follow up. However, in such medical studies, the sample sizes are limited due to restrictions on disease type, study area and medical information availability. Small sample sizes with large proportions of missing information are problematic for researchers trying to understand the experience of the total population. Data modeled without considering this missing information may cause biased results.

A first-order Markov dependence structure is a natural data structure to model the tendency of changes. First, we developed a Markov transition model in a full-likelihood based algorithm to provide robust estimation accounting for non-ignorable missingness, and applied it to data from the Penn Center of Excellence in Cancer Communication Research. Next, we extended the method to a pseudo-likelihood based approach by considering only pairs of adjacent observations to significantly ease the computational complexities of the full-likelihood based method. Finally, we build a two stage pseudo hidden Markov model to analyze the association between quality of life measurements and cancer treatments from a randomized phase III trial in brain cancer patients. By incorporating both selection models and shared parameter models with a hidden Markov model, this approach provides targeted identification of treatment effects. We outline procedures for parameterizing and estimating such models and apply it to the motivating data. Our model provides a simple framework for reducing the multi-dimensional integration in traditional non-ignorable missingness methods into one dimensional integration in the observed likelihood. In addition, the proposed models avoid the problem of specification of the correlation structure of repeated outcomes, instead emphasizing estimation in Markov chain parameters.

This lecture is a part of the Fall 2012 Public Health 519 course "Issues in Global Health."   If you would like to attend as a guest, please contact Dustin Utt (uttd@upenn.edu) to see if there is room available.

Information about the course:  PUBH519 presents an overview of issues in global health from the viewpoint of many different disciplines, with emphasis on economically less developed countries.  Themes include the state of the planet, including populations, resources, and environment; determinants of global health, ethical perspectives, challenges in communicable and non-communicable disease, and intervention strategies.  If you are interested in registering for the entire course, please follow the protocol used in your home school.  This is usually accomplished by checking with the home school program coordinator or advisor.  Medical students should contact Helene Weinberg.

This lecture is a part of the Fall 2012 Public Health 519 course "Issues in Global Health."   If you would like to attend as a guest, please contact Dustin Utt (uttd@upenn.edu) to see if there is room available.

Information about the course:  PUBH519 presents an overview of issues in global health from the viewpoint of many different disciplines, with emphasis on economically less developed countries.  Themes include the state of the planet, including populations, resources, and environment; determinants of global health, ethical perspectives, challenges in communicable and non-communicable disease, and intervention strategies.  If you are interested in registering for the entire course, please follow the protocol used in your home school.  This is usually accomplished by checking with the home school program coordinator or advisor.  Medical students should contact Helene Weinberg.

This lecture is a part of the Fall 2012 Public Health 519 course "Issues in Global Health."   If you would like to attend as a guest, please contact Dustin Utt (uttd@upenn.edu) to see if there is room available.

Information about the course:  PUBH519 presents an overview of issues in global health from the viewpoint of many different disciplines, with emphasis on economically less developed countries.  Themes include the state of the planet, including populations, resources, and environment; determinants of global health, ethical perspectives, challenges in communicable and non-communicable disease, and intervention strategies.  If you are interested in registering for the entire course, please follow the protocol used in your home school.  This is usually accomplished by checking with the home school program coordinator or advisor.  Medical students should contact Helene Weinberg.

This lecture is a part of the Fall 2012 Public Health 519 course "Issues in Global Health."   If you would like to attend as a guest, please contact Dustin Utt (uttd@upenn.edu) to see if there is room available.

Information about the course:  PUBH519 presents an overview of issues in global health from the viewpoint of many different disciplines, with emphasis on economically less developed countries.  Themes include the state of the planet, including populations, resources, and environment; determinants of global health, ethical perspectives, challenges in communicable and non-communicable disease, and intervention strategies.  If you are interested in registering for the entire course, please follow the protocol used in your home school.  This is usually accomplished by checking with the home school program coordinator or advisor.  Medical students should contact Helene Weinberg.

This lecture is a part of the Fall 2012 Public Health 519 course "Issues in Global Health."   If you would like to attend as a guest, please contact Dustin Utt (uttd@upenn.edu) to see if there is room available.

Information about the course:  PUBH519 presents an overview of issues in global health from the viewpoint of many different disciplines, with emphasis on economically less developed countries.  Themes include the state of the planet, including populations, resources, and environment; determinants of global health, ethical perspectives, challenges in communicable and non-communicable disease, and intervention strategies.  If you are interested in registering for the entire course, please follow the protocol used in your home school.  This is usually accomplished by checking with the home school program coordinator or advisor.  Medical students should contact Helene Weinberg.

This lecture is a part of the Fall 2012 Public Health 519 course "Issues in Global Health."   If you would like to attend as a guest, please contact Dustin Utt (uttd@upenn.edu) to see if there is room available.

Information about the course:  PUBH519 presents an overview of issues in global health from the viewpoint of many different disciplines, with emphasis on economically less developed countries.  Themes include the state of the planet, including populations, resources, and environment; determinants of global health, ethical perspectives, challenges in communicable and non-communicable disease, and intervention strategies.  If you are interested in registering for the entire course, please follow the protocol used in your home school.  This is usually accomplished by checking with the home school program coordinator or advisor.  Medical students should contact Helene Weinberg.

This lecture is a part of the Fall 2012 Public Health 519 course "Issues in Global Health."   If you would like to attend as a guest, please contact Dustin Utt (uttd@upenn.edu) to see if there is room available.

Information about the course:  PUBH519 presents an overview of issues in global health from the viewpoint of many different disciplines, with emphasis on economically less developed countries.  Themes include the state of the planet, including populations, resources, and environment; determinants of global health, ethical perspectives, challenges in communicable and non-communicable disease, and intervention strategies.  If you are interested in registering for the entire course, please follow the protocol used in your home school.  This is usually accomplished by checking with the home school program coordinator or advisor.  Medical students should contact Helene Weinberg.

This lecture is a part of the Fall 2012 Public Health 519 course "Issues in Global Health."   If you would like to attend as a guest, please contact Dustin Utt (uttd@upenn.edu) to see if there is room available.

Information about the course:  PUBH519 presents an overview of issues in global health from the viewpoint of many different disciplines, with emphasis on economically less developed countries.  Themes include the state of the planet, including populations, resources, and environment; determinants of global health, ethical perspectives, challenges in communicable and non-communicable disease, and intervention strategies.  If you are interested in registering for the entire course, please follow the protocol used in your home school.  This is usually accomplished by checking with the home school program coordinator or advisor.  Medical students should contact Helene Weinberg.

Rodebaugh Diabetes Center Conference Series Presents:

Topic:  Islet Cell Transplantation

This event has been cancelled