Research Themes
  • Infectious disease (antibiotics, antimicrobial peptides, antibiotic resistance, vancomycin)
  • Neurodegeneration (amyloidogenesis, Alzheimer's disease)
  • Cardiovascular disease (lipoprotein structure and function)
Focus Areas
  • Rational drug design and molecular recognition
  • Protein-lipid interactions (involved in protein folding, misfolding, and amyloidogenesis)
  • Mechanisms and consequences of oxidative lipid membrane damage
Core Technologies
  • Computational chemistry (molecular simulation, molecular graphics)
  • Infrared spectroscopy (internal reflection, supported monolayers, 2D-IR-COSY)
  • Fluorescence spectroscopy (steady state, time resolved)
  • Mass spectrometry (electrospray, triple-quadrupole, ion trap)
Clinical Pharmacology
  • Infectious Diseases, Internal and Emergency Medicine
  • Adverse reactions, drug interactions, pharmacokinetics
    (antibiotics, antiviral & HIV drugs, sedatives, opiates, analgesics, antiinflammatory agents)
  • Clinicopathological correlation
 
 

Paul H. Axelsen MD

105 Johnson Pavilion

University of Pennsylvania

3610 Hamilton Walk

Philadelphia, PA 19104-6084

 

  Office:    215-898-9238

  Lab:        215-898-9766

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