Research Themes
  • Neurodegeneration (amyloidogenesis, Alzheimer's disease, oxidative stress)
  • Infectious disease (antibiotics, antimicrobial peptides, antibiotic resistance, vancomycin)
  • Cardiovascular disease (lipoprotein structure and function)
Focus Areas
  • Mechanisms and consequences of oxidative lipid membrane damage
  • Protein-lipid interactions (involved in protein folding, misfolding, and amyloidogenesis)
  • Rational drug design and molecular recognition
Core Technologies
  • Mass spectrometry (electrospray, triple-quadrupole, ion trap)
  • Computational chemistry (molecular simulation, molecular graphics)
  • Infrared spectroscopy (internal reflection, supported monolayers, 2D-IR-COSY)
  • Fluorescence spectroscopy (steady state, time resolved)
Clinical Pharmacology
  • Infectious Diseases, Internal and Emergency Medicine
  • Adverse drug reactions, drug-drug interactions, pharmacokinetics
    (opioid narcotics, psychoactive agents, antibiotics, antiviral & HIV drugs, antiinflammatory agents, cardiovascular and antihypertensive agents)
  • Clinicopathological correlation
 
 

Paul H. Axelsen MD

1009C Stellar Chance Labs

University of Pennsylvania

422 Curie Boulevard

Philadelphia, PA 19104-6084

 

  Office:    215-898-9238

  Lab:        215-898-9766