Students from any Penn BGS program are welcome to undertake rotations in the lab. Dr. Axelsen is an active member of the graduate groups in:
Biochemistry & Molecular Biophysics
A diverse array of projects may be undertaken, depending on the prior experience and goals of the student. Projects may be designed as small and publishable, with the goal of learning a particular technique, or as exploratory pre-thesis work. In the past, several students have successfully published their rotation projects in first rate journals.
Mass spectrometry projects focusing on protein sequencing, the characterization of post-translational modifications, or the identification and quantitation of lipids and lipid oxidation products are available. These projects generally pertain to questions about the pathogenesis of Alzheimer's disease and biochemical mechanisms of oxidative stress
Projects may be designed around various kinds of analytical spectroscopy, e.g. fluorescence, FTIR, or 2D-IR, also pertaining to Alzheimer's disease and oxidative stress.
Various whole-animal (mouse) and microbiological projects are underway, and may be suitable for students interested in techniques involving stable isotope or radioisotope labeling.
Rational drug design and other computational projects are available, but require advanced computer skills (e.g. C/C++/Fortran programming, Matlab or Linux).
Graduate students interested in a lab rotation should send Dr. Axelsen a message by email indicating their graduate group affiliation, their area of interest within the lab, and the time period for the proposed rotation. The email should be followed up with a telephone call to arrange a meeting.