Bates Laboratory for the study of Host:Viral interactions                                             Perelman School of Medicine at the University of Pennsylvania

 

 

 

   HOME

                       RESEARCH

                                          PUBLICATIONS  

                                                                      PEOPLE

                                                                                   CONTACT


 

Welcome to the Bates Lab

Our lab is interested in the interactions between viruses and their host cells. We use a combination of molecular, cell biological, and genetic tools to understand how viruses invade host cells and evade host defenses. Generally, we focus on viral glycoproteins and host factors that facilitate infection. Although we work with a number of different viral systems, current projects concentrate on several pathogenic viruses including filoviruses (ebolavirus and Marburgvirus) and bunyaviruses (Hantaan, Andes, Sin Nombre, La Crosse).  In addition, we study the intrinsic antiviral factor Tetherin to probe its interaction with ebolavirus glycoproteins and signaling properties.

 

 

 

Current areas of interest

Ebolavirus-host cell interactions

 

Forward genetic screens in human haploid cells

 

Analysis of the cell-intrinsic immune factor tetherin

 

News & Events

 


06.12.12

MJ Drake from MVP joins the lab to complete her PhD thesis!


06.11.12

Ben  Dyer begins his summer rotation


05.23.12

Katy Haines' NPC1 paper is accepted!


05.14.12

Alexa Nicolas joins the lab to complete her undergraduate thesis!


04.13.12

MJ Drake & Rakesh Jambusaria presented at the 2012 BGSA Research Symposium   


03.06.12

Luis Cocka presented at the 2012 CROI Research Symposium


 


 

© The Trustees of the University of Pennsylvania