Department of Psychiatry
Penn Behavioral Health

Neuropsychiatry Section

Neuropsychiatry Section

Monica E. Calkins, PhD

Monica Calkins Dr. Calkins is Assistant Professor of Psychology in Psychiatry at the University of Pennsylvania Perelman School of Medicine. Her research program aims to identify and characterize psychophysiological and neurocognitive features associated with the neurodevelopment of psychotic disorders in young people. The overarching goal of this collaborative research program is to contribute to enhanced early identification of psychosis and increased understanding of its pathophysiological processes. As the Director of Clinical Research Assessment in the Neuropsychiatry Section, Dr. Calkins has led the conceptualization of assessment approaches, development, adaptation and implementation of instruments, training and supervision of assessors, establishment and maintenance of quality control procedures, and use and interpretation of clinical data. She has given numerous local, national and international lectures on topics including biobehavioral risk factors for psychosis, early identification of psychosis, psychopathology assessment, careers in psychology, and research ethics. Dr. Calkins involves and mentors students (undergraduate, graduate, medical, resident, post-doctoral) and research coordinators in research design, data collection, data analysis, and manuscript and thesis preparation. She has received early career awards from the International Congress on Schizophrenia Research and the American College of Neuropsychopharmacology, and a KO8 Mentored Clinical Scientist Award from the NIMH. Dr. Calkins has more than 60 publications in peer-reviewed journals. She is a member of the University of Pennsylvania Institutional Review Board, and has served as an ad-hoc reviewer for NIMH, several international grant review panels, and for more than 24 journals.

Education

  • 1991         B.A.     Temple University: Psychology Honors
  • 2002         Ph.D.  University of Minnesota: Clinical Science and Psychopathology Research
  • 2002-2004          NIMH Post-Doctoral Fellowship in Neuropsychiatry, Department of Psychiatry, University of Pennsylvania School of Medicine
  • 2002-2004 Scottish Rite Schizophrenia Research Fellowship, Department of Psychiatry, University of Pennsylvania School of Medicine

 


Academic Positions

2004-                         Assistant Professor of Psychology, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania

Hospital and Administrative Appointments

2010 – Director of Clinical Research Assessment, Neuropsychiatry Section, Department of Psychiatry, University of Pennsylvania

2013 – Member, Institutional Review Board, University of Pennsylvania

Honors:

2007-2012    Mentored Clinical Scientist Career Development Award (K08): National Institute of Mental Health

2008               Early Career Development Award: American College of Neuropsychopharmacology

2005               Young Investigator Award: International Congress on Schizophrenia Research

2002, 2000   Harrison Gough Research Travel Award, University of Minnesota, Department of Psychology

2001               Graduate Research Partnership Program Award, University of Minnesota Graduate School

2001               Doctoral Dissertation Supplemental Grant, University of Minnesota Graduate School

2000-2001    Doctoral Dissertation Fellowship, University of Minnesota Graduate School

1999-2000    Graduate Research Ethics Participant Grant, National Science Foundation and the Association for Practical and Professional Ethics

1996-1998    Neurobehavioral Aspects of Personality and Psychopathology Training Grant, National Institute of Mental Health, University of Minnesota

1994-1995    Department of Psychology Graduate Fellowship, University of Minnesota


Selected Publications:

Dickson H, Calkins ME, Kohler CG, Hodgins S & Laurens KR (2013) Misperceptions of facial emotion among youth aged 9-14 years who present antecedents of schizophrenia. Schizophrenia Bulletin, in press.

Calkins ME, Ray A, Gur RC, Freedman R. Green MF, Greenwood TA, Light GA, Nuechterlein KH, Olincy A, Radant AD, Seidman Lj, Siever LJ, Silverman JM, Stone WS, Sugar C, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL, Lazzeroni LC, Gur RE (2013). Sex differences in familiality effects on neurocognitive performance in schizophrenia. Biological Psychiatry, 73, 976-984.

Goldenberg PC, Calkins ME, Richard J, McDonald-McGinn D, Zackai E, Mitra N, Emanuel B, Devoto M, Borgmann-Winter K, Kohler C, Conroy CG, Gur RC, Gur RE (2012). Computerized neurocognitive profile in young people with 22q11.2 deletion syndrome compared to youths with schizophrenia and at-risk for psychosis. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 159B :87-93.

Calkins ME, Tepper P, Gur RC, Ragland JD, Klei L, Wiener HW, Richard J, Savage RM, Allen TB, O’Jile J, Devlin B, Kwentus J, Aliyu MH, Bradford DL, Edwards N, Lyons PD, Nimgaonkar VL, Santos AB, Go RCP, Gur RE (2010). Project Among African-Americans to Explore Risks for Schizophrenia (PAARTNERS): Evidence for impairment and heritability of neurocognitive functioning in families of schizophrenia patients. American Journal of Psychiatry, 167, 459-472.

Turetsky BI, Greenwood TA, Olincy A, Radant AD, Braff DL, Cadenhead KS, Dobie DJ, Freedman R, Green MF, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Calkins ME (2008) Abnormal auditory N100 amplitude: A heritable endophenotype in first-degree relatives of schizophrenia probands. Biological Psychiatry, 64, 1051-9.

Calkins ME, Iacono WG & Ones DS (2008). Eye movement dysfunction in first-degree relatives of schizophrenia patients: A meta-analytic evaluation of candidate endophenotypes. Brain & Cognition, 68, 436-461.

Turetsky BI, Calkins ME, Light GA, Olincy A, Radant AD, Swerdlow NR (2007). Neurophysiological endophenotypes of schizophrenia: The viability of selected candidate measures. Schizophrenia Bulletin, 33, 69-94.

Gur RE, Calkins ME, Gur RC, Horan WP, Nuechterlein KH, Seidman LJ, and Stone WS (2007). The Consortium on the Genetics of Schizophrenia (COGS): Neurocognitive endophenotypes. Schizophrenia Bulletin, 33, 49-68.

Calkins ME, Dobie DJ, Cadenhead KS, Olincy A, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Radant AD, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI & Braff DL (2007) The Consortium on the Genetics of Endophenotypes in Schizophrenia (COGS): Model recruitment, assessment, and endophenotyping methods for a multi-site collaboration. Schizophrenia Bulletin, 33, 33-48.

Borgmann-Winter K, Calkins ME, Kniele K, & Gur RE (2006) Assessment of adolescents at risk for psychosis. Current Psychiatry Reports, 8, 313-321.

Aliyu MH, Calkins ME, Swanson CL, Lyons PD, Savage R, May R, Wiener H, Gur RE, Ragland JD, Gur RC, Go RC (2006) Project Among African Americans to Explore Risks for Schizophrenia: Assessment and recruitment methods. Schizophrenia Research, 87, 32-44.

Calkins ME, Gur RC, Ragland JD, & Gur RE (2005). Face recognition memory deficits and visual object memory performance in patients with schizophrenia and their relatives. American Journal of Psychiatry, 162, 1963-1966.

Calkins ME, Curtis CE. & Iacono WG (2004). Antisaccade performance is impaired in medically and psychiatrically healthy biological relatives of schizophrenia patients, Schizophrenia Research, 71, 167-178.

Calkins ME, Curtis CE, Grove WM, & Iacono WG (2004). The multiple dimensions of schizotypy in the first-degree biological relatives of schizophrenia patients. Schizophrenia Bulletin, 30, 317-25.

Calkins ME, Iacono WG, & Curtis CE (2003). Smooth pursuit and antisaccade performance evidence trait stability in schizophrenia patients and their relatives. International Journal of Psychophysiology, 49, 139-146.

Conklin HM, Calkins ME, Dinzeo T, Anderson CA, & Iacono WG (2002). Recognition memory for faces in schizophrenia patients and their first-degree relatives. Neuropsychologia, 40, 2314-2324.

Curtis CE, Calkins ME, & Iacono WG (2001). Saccadic disinhibition in schizophrenia patients and their first-degree biological relatives: A parametric study of the effects of increasing inhibitory load. Experimental Brain Research, 137, 228-236.

Curtis CE, Calkins ME, Grove WM, Feil K, & Iacono WG (2001). Saccadic disinhibition in patients with acute and remitted schizophrenia and their first-degree biological relatives. American Journal of Psychiatry, 158, 100-106.

Calkins ME, Katsanis J, Hammer M, & Iacono WG (2001). The misclassification of blinks as saccades: Implications for investigations of eye movement dysfunction in schizophrenia. Psychophysiology, 38, 761-767.

Calkins ME (2000). Research on human subjects with mental disorders: Case and commentary. In B. Schrag (Ed.) Research ethics: Cases and commentaries (Vol. 4, pp. 3-17). Bloomington, IN: Association for Practical and Professional Ethics.

Calkins ME & Iacono WG (2000). Eye movement dysfunction in schizophrenia: A heritable characteristic for enhancing phenotype definition. American Journal of Medical Genetics, 97, 72-76.