Ruben Gur, PhD
Professor of Psychology
Director of Neuropsychology, the Brain Behavior Laboratory, and the Center for Neuroimaging in Psychiatry
Member of University of Pennsylvania Psychiatry Department since 1984,
Secondary appointments in Radiology and Neurology
Member of the IRG on Clinical Neuroscience at NIH (1992-1996)
Dr. Gur received his B.A. in Psychology and Philosophy from the Hebrew University of Jerusalem, Israel, in 1970 and his M.A. and Ph.D. in Psychology (Clinical) from Michigan State University in 1971 and 1973, respectively. He did Postdoctoral training with E.R. Hilgard at Stanford University and came to Penn as Assistant Professor in 1974. His research has been in the study of brain and behavior in healthy people and patients with brain disorders, with a special emphasis on exploiting neuroimaging as experimental probes. His work has documented sex differences, aging effects, and abnormalities in regional brain function associated with schizophrenia, affective disorders, stroke, epilepsy, movement disorders and dementia. His work has been supported by grants from the NSF, NIH, NIMH, NIA, NINDS, private foundations (Spencer, MacArthur, EJLB) and industry (BioLogic, Novo, Pfizer).
- B.A. Hebrew University of Jerusalem 1967-70
- M.A. Michigan State University 1970-1971
- Ph.D. Michigan State University 1971-1973
- Postdoctoral Fellowship, Stanford University 1973-1974
1971 NIMH Summer Traineeship, Psychiatric Clinic County Juvenile Court Pontiac, Michigan
1971-72 Psychology Internship, Psychiatric Clinic State Prison of Southern Michigan Jackson, Michigan
1972-73 Psychology Internship, Counseling Center Michigan State University East Lansing, Michigan
1973-74 Research Associate, Department of Psychology University, Stanford California
1974-76 Postdoctorate supervised clinical experience of Psychiatry University of Pennsylvania
1974-81 Assistant Professor of Psychology University of Pennsylvania Philadelphia, PA
1981-84 Research Associate Professor of Psychology Neurology and Psychiatry University of Pennsylvania School of Medicine Philadelphia, PA
1984-88 Associate Professor of Psychology with Tenure in, Neurology and Radiology University of Pennsylvania School of Medicine Philadelphia, PA
1988-Present Professor Department of Psychology with Tenure in Psychiatry, Neurology and Radiology University of Pennsylvania, School of Medicine Philadelphia, PA
1965-67, Israeli Defense Forces
Hospital and Administrative Appointents
1974-81, Supervisor, Clinical Training Program, Department of Psychology, University of Pennsylvania , Philadelphia, PA
1982-84, Director of Neuropsychology, Department of Neurology, The Graduate Hospital, Philadelphia, PA
1984-Present, Director of Neuropsychology and the, Brain Behavior Laboratory, Department of Psychiatry, Hospital of the University of Pennsylvania, Philadelphia, PA
2005-Present, Director of the Center for Neuroimaging in Psychiatry, Department of Psychiatry, Hospital of the University of Pennsylvania, Philadelphia, PA
2005-Present, Staff Psychologist, Philadelphia Veterans Administration Medical Center, Philadelphia, PA
Erickson Award for Scientific Excellence for Writing in Hypnosis - 1976
Member, Sigma Xi
Elected to Fellow status, National Academy of Neuropsychologists, 1986
Elected to Fellow status, American Psychological Association, Divisions 6 & 30, 1987
NAMI Stephen V. Logan Award, 1990
Elected to Fellow status, The Association for Psychological Science, 1992
Brain & Behavior Research Foundation - Distinguished Investigator Award - 2007
Brain & Behavior Research Foundation - Lieber Prize for Outstanding Achievement in Schizophrenia Research – 2009 (with Raquel E. Gur, MD, PhD)
American Psychological Association George A. Miller Award - 2009
Merikangas KR, Calkins ME, He J, Burstein M, Chiavacci R, Lateef TM, Ruparel K, Gur RC, Lehner T, Hakonarson H, Gur RE. Comorbidity of Physical and Mental Disorders in the Neurodevelopmental Genomics Cohort Study. Pediatrics, 2015, in press.
Wolf DH, Satterthwaite TD, Calkins ME, Ruparel K, Elliott MA, Hopson RD, Jackson C, Prabhakaran K, Bilker WB, Hakonarson H, Gur RC, Gur RE. Functional Neuroimaging Abnormalities in Psychosis Spectrum Youth. JAMA Psychiatry, 2014, in press.
Bilker WB, Wierzbicki MR, Brensinger CM, Gur RE, Gur RC. Development of abbreviated eight-item form of the Penn verbal reasoning test. Assessment. 2014, 21:669-678.
Schmitt JE, Yi JJ, Roalf DR, Loevner LA, Ruparel K, Whinna D, Souders MC, McDonald-McGinn DM, Yodh E, Vandekar S, Zackai EH, Gur RC, Emanuel BS, Gur RE. Incidental radiologic findings in the 22q11.2 deletion syndrome. AJNR Am J Neuroradiol. 2014, 35:2186-2191.
Honnorat N, Eavani H, Satterthwaite TD, Gur RE, Gur RC, Davatzikos C. GraSP: Geodesic graph-based segmentation with shape priors for the functional parcellation of the cortex. Neuroimage, 2014 [Epub ahead of print]
Vandekar S, Shinohara RT, Raznahan A, Roalf DR, Ross M, Deleo N, Ruparel K, Verma R, Wolf DH, Gur RC, Gur RE, Satterthwaite TD. Topologically Dissociable Patterns of Development of the Human Cerebral Cortex. Journal of Neuroscience. 2014. In press.
Kogler L, Gur RC, Derntl B. Sex differences in cognitive regulation of psychosocial achievement stress: Brain and behavior. Hum Brain Mapp. 2014 Nov 6 [Epub ahead of print]
Eavani H, Satterthwaite TD, Filipovych R, Gur RE, Gur RC, Davatzikos C. Identifying sparse connectivity patterns in the brain using resting-state fMRI. Neuroimage. 2014, 105:286-299.
Moore TM, Reise SP, Gur RE, Hakonarson H, Gur RC. Psychometric Properties of the Penn Computerized Neurocognitive Battery. Neuropsychology. 2014 Sep 5 [Epub ahead of print]
Iannacone S, Leary M, Esposito EC, Ruparel K, Savitt A, Mott A, Richard JA, Gur RC, Abella BS. Feasibility of cognitive functional assessment in cardiac arrest survivors using an abbreviated laptop-based neurocognitive battery. Ther Hypothermia Temp Manag. 2014, 4:131-136.
Robinson, EB, Kirby A, Ruparel K, Yang J, McGrath L, Anttila V, Neale BM, Merikangas K, Lehner T, Sleiman PM, Daly MJ, Gur R, Gur R, Hakonarson H. The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort. Mol Psychiatry. 2014 Jul 15 [Epub ahead of print]
Roalf DR, Vandekar SN, Almasy L, Ruparel K, Satterthwaite TD, Elliott MA, Podell J, Gallagher S, Jackson CT, Prasad K, Wood J, Pogue-Geile MF, Nimgaonkar VL, Gur RC, Gur RE. Heritability of Subcortical and Limbic Brain Volume and Shape in Multiplex-Multigenerational Families with Schizophrenia. Biol Psychiatry. 2014 May 28 [Epub ahead of print]
Calkins ME, Moore TM, Merikangas KR, Burstein M, Satterthwaite TD, Bilker WB, Ruparel K, Chiavacci R, Wolf DH, Mentch FD, Qiu H, Connolly JJ, Sleiman PA, Hakonarson H, Gur RC, Gur RE. The psychosis spectrum in a young U.S. community sample: findings from the Philadelphia Neurodevelopmental Cohort. World Psychiatry. 2014, 13(3), 296-305.
Satterthwaite TD, Shinohara RT, Wolf DH, Hopson RD, Elliott MA, Vandekar SN, Ruparel K, Calkins ME, Roalf DR, Gennatas ED, Jackson C, Erus G, Prabhakaran K, Davatzikos C, Detre JA, Hakonarson H, Gur RC, Gur RE. Impact of puberty on the evolution of cerebral perfusion during adolescence. Proc Natl Acad Sci U S A. 2014, 111(23), 8643-8.
Satterthwaite TD, Wolf DH, Roalf DR, Ruparel K, Erus G, Vandekar S, Gennatas ED, Elliott MA, Smith A, Hakonarson H, Verma R, Davatzikos C, Gur RE, Gur RC. Linked Sex Differences in Cognition and Functional Connectivity in Youth. Cereb Cortex. 2014 Apr 25 [Epub ahead of print].
Roalf DR, Ruparel K, Gur RE, Bilker W, Gerraty R, Elliott MA, Gallagher RS, Almasy L, Pogue-Geile MF, Prasad K, Wood J, Nimgaonkar VL, Gur RC. Neuroimaging predictors of cognitive performance across a standardized neurocognitive battery. Neuropsychology. 2014, 28(2), 161-76.
Roalf DR., Gur RE, Ruparel K., Calkins ME, Satterthwaite TD, Bilker WB, Hakonarson H, Harris LJ & Gur RC. Within-individual variability in neurocognitive performance: Sex and age-related differences in youths from ages 8 to 21. Neuropsychology, 2014, 28(4), 506-518.
Ingalhalikar M, Smith A, Parker D, Satterthwaite TD, Elliott MA, Ruparel K, Hakonarson H, Gur RE, Gur RC, Verma R. Sex Differences in the Structural Connectome of the Human Brain. Proc Natl Acad Sci U S A. 2014, 111, 823-828.
Gur RC, Calkins ME, Satterthwaite TD, Ruparel K, Bilker WB, Moore TM, Savitt AP, Hakonarson H, Gur RE. Neurocognitive Growth Charting in Psychosis Spectrum Youths. JAMA Psychiatry, in press.
Satterthwaite, TD, Wolf, DH, Erus, G, Ruparel, K, Elliott, MA, Gennatas, SD, Hopson, R, Jackson, C, Prabhakaran, K, Bilker, WB, Calkins, ME, Loughead , J, Smith, A, Roalf, DR, Hakonarson, H, Verma, R, Davatzikos, C, Gur, RC, Gur, RE. Functional maturation of the executive system during adolescence. The Journal of Neuroscience, in press.
Greenwood TA, Swerdlow NR, Gur RE, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Green MF, Gur RC, Lazzeroni LC, Nuechterlein KH, Olincy A, Radant AD, Ray A, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Sugar CA, Tsuang DW, Tsuang MT, Turetsky BI, Light GA, Braff DL. Genome-wide linkage analyses of 12 endophenotypes for schizophrenia from the consortium on the genetics of schizophrenia. Am J Psychiatry. 2013 May 1;170(5):521-32. PMID: 23511790
Calkins ME, Ray A, Gur RC, Freedman R, Green MF, Greenwood TA, Light GA, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Sugar C, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL, Lazzeroni LC, Gur RE. Sex differences in familiality effects on neurocognitive performance in schizophrenia. Biol Psychiatry. 2013 May 15;73(10):976-84. PMID: 23395246
Thomas ML, Brown GG, Gur RC, Hansen JA, Nock MK, Heeringa S, Ursano RJ, Stein MB. Parallel psychometric and cognitive modeling analyses of the Penn Face Memory Test in the Army Study to Assess Risk and Resilience in Servicemembers. J Clin Exp Neuropsychol. 2013 Mar;35(3):225-45. PMID: 23383967
Satterthwaite TD, Ruparel K, Loughead J, Elliott MA, Gerraty RT, Calkins ME, Hakonarson H, Gur RC, Gur RE, Wolf DH. Being right is its own reward: load and performance related ventral striatum activation to correct responses during a working memory task in youth. Neuroimage. 2012 Jul 2;61(3):723-9. PMID: 22484308
Gur RC, Richard J, Calkins ME, Chiavacci R, Hansen JA, Bilker WB, Loughead J, Connolly JJ, Qiu H, Mentch FD, Abou-Sleiman PM, Hakonarson H, Gur RE. Age group and sex differences in performance on a computerized neurocognitive battery in children age 8-21. Neuropsychology. 2012 Mar;26(2):251-65. PMID: 22251308
Gur RC, Richard J, Hughett P, Calkins ME, Macy L, Bilker WB, Brensinger C, Gur RE. A cognitive neuroscience-based computerized battery for efficient measurement of individual differences: standardization and initial construct validation. J Neurosci Methods. 2010 Mar 30;187(2):254-62. PMCID: PMC2832711
Glocker ML, Langleben DD, Ruparel K, Loughead JW, Valdez JN, Griffin MD, Sachser N, Gur RC. Baby schema modulates the brain reward system in nulliparous women. Proc Natl Acad Sci 2009 106:9115-9119. PMCID: PMC2690007
Almasy L, Gur RC, Haack K, Cole SA, Calkins ME, Peralta JM, Hare E, Prasad K, Pogue-Geile MF, Nimgaonkar V, Gur RE. A Genome Screen for Quantitative Trait Loci Influencing Schizophrenia and Neurocognitive Phenotypes. Am J Psychiatry. 2008, 103, 218-228.
Gur RC, Turetsky BI, Loughead J, Waxman J, Snyder W, Ragland JD, Elliot M, Bilker WB, Arnold SE, Gur RE. Hemodynamic responses in neural circuitries for detection of visual target and novelty: An event-related fMRI study. Human Brain Mapping. 2007, 28, 263-274.
Gur RC. Brain maturation and its relevance to understanding criminal culpability of juveniles. Current Psychiatry Reports. 2005, 7, 292-296.
Gur RC, Schroeder L, Turner T, McGrath C, Chan RM, Turetsky BI, Alsop D, Maldjian J, Gur RE. Brain activation during facial emotion processing. NeuroImage, 2002, 16, 651-662.
Gur RC, Gunning-Dixon FM, Turetsky BI, Bilker WB, Gur RE. Brain Region and sex differences in age association with brain volume: A quantitative MRI study of healthy young adults. Am J Geriatric Psychiatry, 2002, 10,72-80.
Gur RC, Ragland JD,Moberg PJ,Turner TH, Bilker WB, Kohler C, Siegel SJ, Gur RE. Computerized Neurocognitive Scanning: I. Methodology and validation in healthy people. Neuropsychopharmacology, 2001, 25, 766-776.
Gur RC, Alsop D, Glahn D, Petty R, Swanson CL, Maldjian JA, Turetsky BI, Detre JA, Gee J, Gur RE. An fMRI study of sex differences in regional activation to a verbal and a spatial task. Brain and Language, 2000, 74, 157-170.
Gur RC, Turetsky BI, Matsui M, Yan M, Bilker W, Hughett P, Gur RE. Sex differences in brain gray and white matter in healthy young adults. Journal of Neuroscience, 1999, 19, 4065-4072.
Schneider F, Grodd W, Weiss U, Klose U, Mayer KR, Nagele T, Gur RC. Functional MRI reveals left amygdala activation during emotion. Psychiatry Research:Neuroimaging Section, 1997, 76, 75-82.
Gur RC, Ragland JD, Mozley LH, Mozley PD, Smith R, Alavi A, Bilker W, Gur RE. Lateralized changes in regional cerebral blood flow during performance of verbal and facial recognition tasks: Correlations with performance and"Effort". Brain and Cognition, 1997, 33, 388-414
Schneider F, Gur RE, Mozley LH, Smith RJ, Mozley PD, Censits DM, Alavi A, Gur RC. Mood effects on limbic blood flow correlate with emotional self-rating. A PET study with oxygen-15 labeled water. Psychiatry Research, 1995, 61, 265-283.