Recent Publications

Below is a list of recent publications sorted by areas of interest. Browse the whole list, or jump to any section.

Aging - Viral - Sporulation & Gametogenesis - Cancer/p53 - General - Reviews

Aging (Back to top)

Kozak, M.L., Chavez, A., Dang, W., Berger, S.L., Ashok, A., Guo, X., Johnson, F.B. Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction. (2010) The EMBO journal, 29 (1), pp. 158-170.

Dang, W., Steffen, K.K., Perry, R., Dorsey, J.A., Johnson, F.B., Shilatifard, A., Kaeberlein, M., Kennedy, B.K., Berger, S.L. Histone H4 lysine 16 acetylation regulates cellular lifespan (2009) Nature, 459 (7248), pp. 802-807.

Viral (Back to top)

Placek, B.J., Huang, J., Kent, J.R., Dorsey, J., Rice, L., Fraser, N.W., Berger, S.L. The histone variant H3.3 regulates gene expression during lytic infection with herpes simplex virus type 1 (2009) Journal of Virology, 83 (3), pp. 1416-1421.

Huang, J., Kent, J.R., Placek, B., Whelan, K.A., Hollow, C.M., Zeng, P.-Y., Fraser, N.W., Berger, S.L. Trimethylation of histone H3 lysine 4 by Set1 in the lytic infection of human herpes simplex virus 1 (2006) Journal of Virology, 80 (12), pp. 5740-5746.

Sporulation & Gametogenesis (Back to top)

Bryant JM, Donahue G, Wang X, Meyer-Ficca M, Luense LJ, Weller AH, Bartolomei MS, Blobel GA, Meyer RG, Garcia BA, Berger SL. Characterization of BRD4 during mammalian post-meiotic sperm development.  (2015) Mol Cell Biol., in press

Bryant, J.M., Berger, S.L. Low-hanging fruit: Targeting Brdt in the testes (2012) EMBO Journal, 31 (19), pp. 3788-3789.

Bryant, J.M., Govin, J., Zhang, L., Donahue, G., Pugh, B.F., Berger, S.L. The linker histone plays a dual role during gametogenesis in Saccharomyces cerevisiae (2012) Molecular and Cellular Biology, 32 (14), pp. 2771-2783.

Govin J, Dorsey J, Gaucher J, Rousseaux S, Khochbin S, Berger SLSystematic screen reveals new functional dynamics of histones H3 and H4 during gametogenesis. (2010) Genes & Development, 24:1772-86.

Govin J., Schug J., Krishnamoorthy T., Dorsey J., Khochbin S., Berger, S.L. Genome-wide mapping of histone H4 serine-1 phosphorylation during sporulation in Saccharomyces cerevisiae (2010) Nucleic Acids Res., 38 (14), pp. 4599-606. (Protocols available)

Govin, J., Berger, S.L. Genome reprogramming during sporulation (2009) International Journal of Developmental Biology, 53 (2-3), pp. 425-432.

Krishnamoorthy, T., Chen, X., Govin, J., Cheung, W.L., Dorsey, J., Schindler, K., Winter, E., Allis, C.D., Guacci, V., Khochbin, S., Fuller, M.T., Berger, S.L. Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis (2006) Genes and Development, 20 (18), pp. 2580-2592.

Cancer / p53 (Back to top)

Huang, J., Sengupta, R., Espejo, A.B., Lee, M.G., Dorsey, J.A., Richter, M., Opravil, S., Shiekhattar, R., Bedford, M.T., Jenuwein, T., Berger, S.L. p53 is regulated by the lysine demethylase LSD1 (2007) Nature, 449 (7158), pp. 105-108.

Huang, J., Perez-Burgos, L., Placek, B.J., Sengupta, R., Richter, M., Dorsey, J.A., Kubicek, S., Opravil, S., Jenuwein, T., Berger, S.L. Repression of p53 activity by Smyd2-mediated methylation (2006) Nature, 444 (7119), pp. 629-632.

General (Back to top)

Edwards, C.R., Dang, W., Berger, S.L. Histone H4 lysine 20 of Saccharomyces cerevisiae is monomethylated and functions in subtelomeric silencing. (2011) Biochemistry, 50 (48), pp 10473-10483.

Bungard, D., Fuerth, B.J., Zeng, P.Y., Faubert, B., Maas, N.L., Viollet, B., Carling, D., Thompson, C.B., Jones, R.G., Berger, S.L. Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. (2010) Science, 329 (5996), pp.1201-5. (Protocols available)

Bonasio, R., Zhang, G., Ye, C., Mutti, N.S., Fang, X., Qin, N., Donahue, G., Yang, P., Li, Q., Li, C. Zhang, P., Huang, Z., Berger, S.L., Reinberg, D., Wang, J., Liebig, J. Genomic comparison of the ants Camponotus floridanus and Harpegnathos saltator. (2010) Science, 329 (5995), pp. 1068-71. (Protocols available)

Walter, W., Clynes, D., Tang, Y., Marmorstein, R., Mellor, J., Berger, S.L. 14-3-3 Interaction with histone H3 involves a dual modification pattern of phosphoacetylation (2008) Molecular and Cellular Biology, 28 (8), pp. 2840-2849.

Wyce, A., Xiao, T., Whelan, K.A., Kosman, C., Walter, W., Eick, D., Hughes, T.R., Krogan, N.J., Strahl, B.D., Berger, S.L. H2B Ubiquitylation Acts as a Barrier to Ctk1 Nucleosomal Recruitment Prior to Removal by Ubp8 within a SAGA-Related Complex (2007) Molecular Cell, 27 (2), pp. 275-288.

Ingvarsdottir, K., Edwards, C., Lee, M.G., Lee, J.S., Schultz, D.C., Shilatifard, A., Shiekhattar, R., Berger, S.L. Histone H3 K4 demethylation during activation and attenuation of GAL1 tanscription in Saccharomyces cerevisiae (2007) Molecular and Cellular Biology, 27 (22), pp. 7856-7864.

Nathan, D., Ingvarsdottir, K., Sterner, D.E., Bylebyl, G.R., Dokmanovic, M., Dorsey, J.A., Whelan, K.A., Krsmanovic, M., Lane, W.S., Meluh, P.B., Johnson, E.S., Berger, S.L. Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications (2006) Genes and Development, 20 (8), pp. 966-976.

Reviews (Back to top)

Berger, S.L., Kouzarides, T., Shiekhattar, R., Shilatifard, A. An operational definition of epigenetics (2009) Genes and Development, 23 (7), pp. 781-783.

Berger, S.L. Out of the jaws of death: PRMT5 steers p53 (2008) Nature Cell Biology, 10 (12), pp. 1389-1390.

Huang, J., Berger, S.L. The emerging field of dynamic lysine methylation of non-histone proteins (2008) Current Opinion in Genetics and Development, 18 (2), pp. 152-158.

Berger, S.L. The complex language of chromatin regulation during transcription (2007) Nature, 447 (7143), pp. 407-412.

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