CAMB 510 Immunology for CAMB Students

IMMUNOLOGY for CAMB students: CAMB 510     Spring 2007

Course Directors: Yvonne Paterson, Chris Hunter, David Weiner

From 9:30 to 11 in 209 Johnson on Monday and Wednesday and 1311 Blockley Hall on Friday

Part 1. Basic aspects of the Immune Response – how the immune system acts like a system: Moderator: Chris Hunter

January

            8       Introduction to cells and tissues of the Immune system - Chris Hunter            

            10     Innate Immunity  I  – Chris Hunter

Friday  12     Innate Immunity II – Kate Sullivan

            15     MLK birthday

            17     Innate immunity III – Sara Cherry

Friday  19     Innate Immunity –IV Kate Sullivan

            22     Genetics of the MHC– Mickey Marks

            24     Antigen processing and presentation – Mickey Marks          

Friday  26     Transgenic and knock-out mice – Terri Laufer     

            29     Genetics of Immunoglobulins and T cell receptors - Luning- Prak

            31     B  cell developmental biology – Luning-Prak        

February

Friday  2      Antibody – what is it good for? - Don Siegel

              5     T cell developmental biology – Terri Laufer

              7     T cell Lymphocyte Activation (life and death of T cells) – Andrew Wells

Friday   9      Lymphoid organization/structure – Michael May

            12     Tracking T cell responses – John Wherry

            14     Lymphocyte memory  – John Wherry            

Friday  16.    Exam tutorial or Exam Part 1 (1.5 hours).          

Monday February 19. Exam Part 1 continued (3 hours)

Part 2 – The immune response in infection and how this impacts on vaccine design: Moderator: David Weiner

 21 Mucosal Immune System – David Artis

Friday 23Mucosal vaccines strategies and testing – Paul Offit

26        Immune response to bacterial infections – Jeff Weiser

28            Humoral immune responses in preventing and controlling viral infection – Bob Doms

March   

Friday 2Immune response to acute viral infections -Drew Weissman

5            Immune responses to chronic viral infections – Kyong-MiChang

7 The problems and pitfalls of measuring human immune response to

  infection – Mike Betts

Friday 9 Viral evasion of the immune response –  Jim Hoxie

12 Immune response to HIV – Guido Silvestri

14        Global challenges to Vaccine design – David Weiner

Friday16 Immunity to parasitic infections – Ed Pearce

19  The modulation of the immune response by parasitic infections– Jean Boyer,

•    Parasite evasion of the immune system 1 - Ed Pearce

23           Changes in the immune response on aging – Avinash Bhandoola

Part 3 – Immunopathology and Tumor Immunology:

            Moderator, Yvonne Paterson

26        Inherited  immunodeficiency – Jordan Orange

28        Gene Therapy for immunodeficiency disease – Elena Perez

Friday 30 The Transformed Tumor Phenotype and Principles of Molecular Pathogenesis–William Lee

April    

2          Allergy -  Arnie Levinson

4          Tumor Immunology – Immunosurveillance of tumors – Yvonne Paterson           

Friday 6 Immunotherapeutic approaches to cancer – Yvonne  Paterson,               

9          Immunological tolerance B cells – Nina Luning-Prak

11        Immunological tolerance T cells – Youhai Chen

Friday 13 Immune responses in immune privileged sites – Chris Hunter,

16        Autoimmunity -  Youhai Chen

18        Transplantation Immunology -  Wayne Hancock

Friday 20 How immunosuppressive drugs work – Wayne Hancock

Monday April 23. Exam Part 2*.(3 hours)

*The students get the exam two days ahead of time and then have to come into class to actually answer the questions in a closed book 3 hour exam.