CAMB 510 Immunology for CAMB Students

IMMUNOLOGY for CAMB students: CAMB 510     Spring 2008

Course Directors: Yvonne Paterson, Chris Hunter, Guido Silvestri

From 9:30 to 11 in 252 BRB II/III

Part 1. Basic aspects of the Immune Response – how the immune system acts like a system: Moderator: Chris Hunter/John Wherry

January

14                 Introduction to cells and tissues of the Immune system – Chris Hunter            

16                 Innate Immunity  I  – Sara Cherry

Friday  18     Innate Immunity II – Chris Hunter

21                 MLK birthday

23                 Innate immunity III – Kate Sullivan

Friday  25     Innate Immunity IV– Kate Sullivan

28                 Genetics of the MHC – Laurence Eisenlohr

29                 Antigen processing and presentation – Laurence Eisenlohr

February       

Friday    1     B cell developmental biology – Mike Cancro

4                   B cell homeostasis and effector functions – Mike Cancro

 6                  T cell developmental biology – Terri Laufer

Friday    8      Functional heterogeneity in T cell subsets – Chris Hunter

 11               Transgenic and knock-out mice – Terri Laufer

13                 Lymphoid organization/structure – Gudrun Debes

Friday    15   Leukocyte trafficking – Gudrun Debes

18                 T cell Lymphocyte Activation (life and death of T cells – John Wherry

20                 Lymphocyte memory  – John Wherry

Friday  22.    Exam tutorial or Exam Part 1 (1.5 hours).          

Monday February 25. Exam Part 1 continued (3 hours)

Part 2 – The immune response in infection and how this impacts on vaccine design: Moderator: Guido Silvestri

 27       Global challenges to Vaccine design – David Weiner

Friday 29      Mucosal vaccines strategies and testing – Paul Offit

March

3                   Innate immunity to bacteria– Jeff Weiser

5                  Mucosal immune system – David Artis

Friday 7        Humoral immunity in preventing and controlling viral infection – Nina Prak

10                Viral immune evasion  - Susan Ross

12         Immunology of viral CNS infections - Glenn Rall

Friday 14      Changes in the immune response on aging – Avinash Bhandoola

17          Cellular immune response to HIV and other human viruses– Mike Betts

19                Humoral immune response to HIV –  Jim Hoxie

Friday 21     Immunity to parasitic infections - Ed Pearce

24                 Adaptive immunity to bacteria: implications for vaccine design– Hao Shen

26                 Parasite evasion of the immune system  – Ed Pearce

Friday 28         Immunopathology of primate lentiviral infections – Guido Silvestri

Part 3 – Immunopathology and Tumor Immunology:

            Moderator, Yvonne Paterson, Youhai Chen

31                    Transplantation Immunology –  Jonathan Maltzman

April

2                How immunosuppressive drugs work – Jonathan Maltzman

Friday 4     Allergy –  Angela Haczku 

7                Tumor Immunology – Immunosurveillance of tumors – Yvonne Paterson     

9                Suppression and regulation of the immune response to tumors. – James Riley

Friday 11   Immunotherapeutic approaches to cancer – Yvonne  Paterson           

14              Immunological tolerance B cells – Nina Luning Prak

16              Immunological tolerance T cells – Youhai Chen

Friday 18  Immune responses in immune privileged sites – Chris Hunter

21              Autoimmunity –  Youhai Chen

23              Inherited  immunodeficiency – Jordan Orange

Friday 25   Gene Therapy for immunodeficiency disease – Elena Perez – Hand out exam.

Monday April 28. Exam Part 2* (3 hours)

*The students get the exam two days ahead of time and then come into class to actually answer the questions in a “closed book” 3 hour exam