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 Biomedical Graduate Studies

IMUN 508 Immune Responses

IMUN 508 Course Description

This course is designed to (1) extend the basic immunology principles addressed in 506, and (2) apply the fundamental principles of the mechanism of immune recognition and development presented in 506 to the immune response in health and disease in vivo. The course is designed as a series of minicourses, which change from year to year. Each minicourse will cover an important topic in immunology in detail.  Each minicourse will consist of 6 hours/week for 4 weeks. The semester will be divided into 3 sessions.  The minicourses will be taught as a combination of formal lectures and seminar-format discussions of relevant literature. Each minicourse will have a slightly different format.  Non-first year immunology graduate students/postdocs/etc may petition the instructors if they wish to take a minicourse.

Pre-requisites:             Immunology 506 and permission of director

Offered:                       Spring Semester (M, W, F 9:00 - 11:00)

Credit:                          2 c.u.

Minicourses SCHEDULED FOR Spring Semester 2007

Session 1: Monday, January 8 – Friday, February 2, 2007

Transcription factors and regulation of lymphocyte development. 

Warren Pear, M.D., Ph.D. and Avinash Bhandoola, Ph.D.

        This course covers the general principles of transcription and applies them to immune development.  The basic format is a one-hour lecture followed by a student-run journal club. Grades are based on journal club presentations, a short review article, and class participation.

Session 2: Monday, February 5 – Friday, March 2, 2007

Mini course in Tumor immunology. 

Yvonne Paterson, Ph.D. and James Riley, Ph.D.

        This mini course will take the form of 2 broad topics. The first will cover the fundamental principles of tumor immunology and the second will focus on how to harness the immune system to eliminate cancer.  Each week has 6 contact hours 4 of which will involve didactic presentations/discussions and two of which will be in the form of journal club presentations by the students. Thus there will be 8 two hour lectures and four journal discussions. There will be one final exam that will take the form of a written, closed-book, in-class exam of three hours. However you will be allowed to take the exam questions home for two days to select the questions you wish to answer and formulate your answers before taking the exam.

Instructors include Drs. Riley, Paterson, Lee, Pear, June and Vonderheide

 

Session 3: Monday, March 19 – Friday, April 13, 2007

Experiments of nature and engineered immune deficiencies. 

Peter Felsburg, V.M.D., Ph.D. and Kathleen Sullivan, M.D., Ph.D.

        This course will explore inherited immune deficiencies seen in human and offer comparisons with murine models.  The mechanisms underlying disease will be discussed including signaling pathways and cell-cell interactions.  The format of the course is a combination of faculty lecture and student presentations.