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CAMB 605 1st Year Seminar

CAMB 605 - First Year Seminar (Fall 2007): Course Syllabus

Weeks 1-6: Students lead round-table discussion of assigned papers.

Weeks 7-12: Students lead round-table discussion of papers selected from assigned topics.

Presentation 1: Faculty chosen papers (Weeks 1-6)

September 18: Paper 1 (Doug Epstein), Paper 2 (Doug Epstein)

September 25: Paper 3 (John Seykora), Papers 4a and 4b (Ben Black)

     4a.  Tomita, J., et al. (2005). No Transcription-Translation Feedback in Circadian

Rhythm of KaiC Phosphorylation. Science 307: 251-254.

     4b. Nakajima, M., et al. (2005). Reconstitution of Circadian Oscillation of

           Cyanobacterial KaiC Phosphorylation in Vitro. Science 308: 414-415.

October 2: Paper 5 (Doron Greenbaum), Paper 6 (Doron Greenbaum)

October 9: Paper 7 (Vivian Cheung), Paper 8 (Vivian Cheung)

      9.  He, L., et al. (2007). A microRNA component of the p53 tumour suppressor     network. Nature 447: 1130-1134.

     10.  Aitman, T.J., et al. (2006). Copy number polymorphism in Fcgr3 predisposes to           glomerulonephritis in rats and humans. Nature 439: 851-855.

October 16: Paper 9 (Dwight Stambolian), Paper 10 (Mike Betts)

11. Klein, R.J., et al. (2005). Complement Factor H Polymorphism in Age-Related             Macular Degeneration. Science 308: 385-389.

12. Stern-Ginossar, N., et al. (2007). Host Immune System Gene Targeting by a Viral   miRNA. Science 317: 376-380.

October 23: Paper 11 (Wei Tong), Paper 12 (Catherine Lee May)

7.   Yilmaz, O., et al. (2006). Pten Dependence Distinguishes Haematopoietic Stem             Cells from Leukaemia-Initiating Cells. Nature 441: 475-482.

      8.   Collombat, P., et al. (2007). Embryonic Endocrine Pancreas and Mature b cells Acquire a and PP Cell Phenotypes upon Arx Misexpression. J Clin. Inv. 117: 961-970

Presentation 2: Student chosen papers from list of topics (Weeks 7-12)

October 30: Topic 1 (John Seykora), Topic 2 (Mike Betts)

  1. Murine models of psoriasis
  2. Pathogen modulation of immune responses

November 6: Topic 3 (Catherine Lee May), Topic 4 (Catherine Lee May)

  1. Endodermal organ formation
  2. Beta cell growth and survival in diabetes mellitus

November 13: Topic 5 (Ben Black), Topic 6 (Ben Black)

November 20: Topic 7 (Vivian Cheung), Topic 8 (Doron Greenbaum)

  1. Genetic basis of human disease
  2. The function of proteases in metastasis

November 27: Topic 9 (Wei Tong), Topic 10 (Wei Tong)

  1. Hematopoietic stem cells and leukemia
  2. The hematopoietic stem cell niche

December 4: Topic 11 (Doug Epstein), Topic 12 (Dwight Stambolian)

  1. Cis regulatory changes in animal evolution
  2. Iron regulatory proteins and cataract