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PHRM 640 Topics in Cancer Pharm

Wednesdays 1-3 pm

M100 John Morgan Building (Pharmacology Library)

Course directors:

Wenchao Song, (song@spirit.gcrc.upenn.edu)

Judy Meinkoth (meinkoth@pharm.med.upenn.edu)

Cancer Pharmacology Staff Assistant

Christine Shwed, 853 BRB II/III, 215-573-9885, 9887

(christine@spirit.gcrc.upenn.edu)

Reviews of current literature on topics such as cancer cell signalling, cancer genetics, hormonal carcinogenesis, environmental carcinogens, chemo- and gene therapy of cancer, cancer epidemiology and prevention. New hypotheses in cancer etiology, prevention and treatment will be discussed as they appear in the literature. The aim of the course is to introduce the students to the latest development in the above areas related to cancer pharmacology. Offered in the fall semester.

Date

Topic

Lecturer

9/12

Introduction/Organization

Judy Meinkoth

W. Song

9/19

Protein kinase C and tumor promotion

Marcelo Kazanietz

9/26

Chemical Carcinogenesis

Trevor Penning

10/03

Apoptosis

Xiaolu Yang

10/10

DNA adducts and DNA repair

Ian Blair

10/17

Genetic factors and cancer

Kate Nathanson

10/24

Oncogenes and tumor suppressors

Jeff Field

10/31

Sonic Hedgehog signaling in cancer

Nati Riobo

11/07

Signal transduction Therapy

Jeff Field

11/14

Cancer Chemo-prevention

Ann Kennedy

11/28

Gene and cellular therapy of cancer

Carl June

12/05

Small G proteins and cancer

Margaret Chou

12/12

Angiogenesis as a target for cancer therapy

Bill Lee