NICOLAI M. DOLIBA, Ph.D., D.SC.

Research Assistant Professor of Biochemistry and Biophysics

TRC12-131A
Translational Research Center
3400 Civic Center Blvd.
Philadelphia, PA 19104-5160
T: (215) 898-4366 (office)
T: (215) 898-0313 (lab)
T: (215) 898-7705 (lab)
F: (215) 898-5408.
nicolai@mail.med.upenn.edu

Ph.D. Lviv Institute of Medicine, Lviv, Ukraine (1986) Physiology
D.Sc. Lviv State University, Lviv, Ukraine (1993) Physiology

DESCRIPTION OF RESEARCH INTERESTS:

Dr. Doliba has focused on the role of bioenergetics, ion transport and metabolic coupling factors in nutrient- and drug-stimulated insulin release at normal conditions and during diabetes mellitus.

Using combinations of different methods and approaches, including ³¹P, ¹³C, and ¹H Nuclear Magnetic Resonance Spectroscopy techniques, polarographic and phosphorescence methods of measuring O₂ consumption, Ca²⁺ imaging and others, he attempts to directly address the essential mechanisms of stimulus-secretion coupling in pancreatic islets.