NICOLAI M. DOLIBA, Ph.D., D.SC.
Research Assistant Professor of Biochemistry and Biophysics
Translational Research Center
3400 Civic Center Blvd.
Philadelphia, PA 19104-5160
T: (215) 898-4366 (office)
T: (215) 898-0313 (lab)
T: (215) 898-7705 (lab)
F: (215) 898-5408.
Ph.D. Lviv Institute of Medicine, Lviv, Ukraine (1986) Physiology
D.Sc. Lviv State University, Lviv, Ukraine (1993) Physiology
DESCRIPTION OF RESEARCH INTERESTS:
Dr. Doliba has focused on the role of bioenergetics, ion transport and metabolic coupling factors in nutrient- and drug-stimulated insulin release at normal conditions and during diabetes mellitus.
Using combinations of different methods and approaches, including 31P, 13C, and 1H Nuclear Magnetic Resonance Spectroscopy techniques, polarographic and phosphorescence methods of measuring O2 consumption, Ca2+ imaging and others, he attempts to directly address the essential mechanisms of stimulus-secretion coupling in pancreatic islets.