Isothermal Titration Calorimetry (ITC)

ITC is a quantitative technique that can determine the thermodynamic parameters of interactions in solution.  The most common application is the study of the binding of small molecules to larger macromolecular target, although it can also be employed to study other macromolecular interactions. The technique requires samples of the highest purity, as validated by other complementary measures. 

  • The MicroCal ITC200 Microcalorimeter includes temperature control, 200 µL sample cell and 40 µL injection syringe.
ITC200 Microcalorimeter


Prices for the Penn Community* (FY 2017):

Initial training: $100/experiment – mandatory for first use
Instrument use: $20/hour


This instrument is located within the Department at 810 Stellar-Chance Laboratory



Kushol Gupta


810 Stellar-Chance Laboratories

Prices for the Penn Community*:

Initial training: $100/experiment**

Instrument use: $20/hour


Download a billing form:

.docx or .pdf


includes all schools of Penn as well as HUP, CHOP, and Wistar


mandatory for first use