Microscale Thermophoresis (MST)

MST is a relatively new technology that monitors the movement of fluorescently labelled particles along a microscopic temperature gradient in solution.  Changes in the hydration shell of the molecule change the movement of the particle along the gradient.  This information can be fit with binding isotherms to derive kinetic constants.

  • Nanotemper Microscale Thermophoresis Monolith NT.115Pico is equipped with one Pico detector with highly optimized fluorescence channel.

Prices for the Penn Community* (FY 2017):

Initial training: $25/rack – mandatory for first 5 racks
Instrument use: $10/rack
Staff assistance: may be discussed if needed

 

This instrument is located within the department at 910 Stellar-Chance Laboratory

Contact:

Kushol Gupta

kgupta@mail.med.upenn.edu

 

Location:

910 Stellar-Chance Laboratories

 

Prices for the Penn Community*:

Initial training: $25/rack**

Instrument use: $10/rack

 

Download a billing form:

.docx or .pdf

*

includes all schools of Penn as well as HUP, CHOP, and Wistar

**

mandatory for first five racks