Microscale Thermophoresis (MST)

MST is a relatively new technology that monitors the movement of fluorescently labelled particles along a microscopic temperature gradient in solution.  Changes in the hydration shell of the molecule change the movement of the particle along the gradient.  This information can be fit with binding isotherms to derive kinetic constants.

  • Nanotemper Microscale Thermophoresis Monolith NT.115Pico is equipped with one Pico detector with highly optimized fluorescence channel.

Prices for the Penn Community* (FY 2017):

Initial training: $25/rack – mandatory for first 5 racks
Instrument use: $10/rack
Staff assistance: may be discussed if needed


This instrument is located within the department at 910 Stellar-Chance Laboratory


Kushol Gupta




910 Stellar-Chance Laboratories


Prices for the Penn Community*:

Initial training: $25/rack**

Instrument use: $10/rack


Download a billing form:

.docx or .pdf


includes all schools of Penn as well as HUP, CHOP, and Wistar


mandatory for first five racks