Analytical Ultracentrifugation

With this specialized instrumentation, the migration of a molecule subjected to high centrifugal force can be monitored in real time using optical detection. The change in sample concentration relative to the axis of rotation can be used to determine fundamental solution properties of the macromolecule of interest, including size, shape, mass, equilibrium constants of association. Requires samples of the highest purity, as validated by other complementary measures. 

  • The Beckman XL-A analytical ultracentrifuge with temperature-control, 50.2Ti Titanium rotor and appropriate cell assemblies for sedimentation velocity and sedimentation equilibrium analyses.

Analytical Ultracentrifuation

ANALYTICAL ULTRACENTRIFUGE

Prices for the Penn Community*:

Velocity experiment: $40/day
Equilbrium exp: $100/day
Both services include assistance with data analysis

 

This instrument is located within the Department at 810 Stellar-Chance Laboratory

Contact:

Kushol Gupta

kgupta@mail.med.upenn.edu

Location:

810 Stellar-Chance Laboratories

Prices for the Penn Community*:

Velocity experiment: $40/day

Equilbrium exp: $100/day

(both include assistance with data analysis)

 

Download a billing form:

.docx or .pdf

*

includes all schools of Penn as well as HUP, CHOP, and Wistar