Faculty by Research Interests

Control of gene expression and cellular programming
Dreyfuss, Garcia, Gardini, Gupta, Kohli, Lewis, Liu, Lynch, Marmorstein, Murakami, Shorter, VanDuyne, Wand, Wilusz  

Cell signaling and intracellular trafficking
Black,  Discher, Dreyfuss, Garcia, Kohli, Lynch, Wand

Chemical and structural biology
Axelsen, Black, Englander, Gupta, Lewis, Marmorstein, Moiseenkova-Bell, Murakami, Penning, Petersson, Sellmyer, Sharp, Shorter,  Skordalakes, Speicher, Tommos, VanDuyne, Vinogradov, Wand, Wilusz

Bioenergetics, metabolism, and membranes  
Axelsen, Daldal, Discher, Doliba, Englander, Goldman, Matschinsky, Penning, Sharp, Vinogradov, Wilson

 

Training opportunities are available in the following laboratories:

Paul H. Axelsen, MD | Protein misfolding diseases and pathological protein-lipid interactions; rational drug design

Ben E. Black, PhD | Chromosome segregation; chromatin structure; epigenetic centromere specification; hydrogen/deuterium exchange

Fevzi Daldal, PhD | Genetics, structure-function, regulation and biogenesis of cytochromes

Bohdana Discher PhD | Designing and interfacing proteins with membranes and electronic devices

Nicolai Doliba, PhD | Bioenergetics, metabolism, and membranes

Gideon Dreyfuss, PhD | Nuclear transport, hnRNP complexes, RNA-binding proteins, spinal muscular Atrophy

P. Leslie Dutton, PhD | Oxidoreductase engineering; design and chemical synthesis of redox proteins

S. Walter Englander, PhD | Protein folding; structure, structure change, and dynamics; H-exchange; NMR

Benjamin A. Garcia, PhD | Quantitative proteomics for understanding signaling pathways

Alessandro Gardini, PhD | Understanding the role of enhancers and noncoding RNAs in transcriptional  regulation in mammals

Jerry Glickson, PhD | Molecular imaging: NMR spectroscopy and imaging of cancer; optical imaging of cancer; nanotechnology

Yale E. Goldman, MD, PhD | Molecular motors and protein synthesis studied by single molecule Biophysics

Kushol Gupta, PhD | Structural biology of large macromolecular assemblies that regulate genetic information; X-ray crystallography; small-angle X-ray and neutron scattering

Rahul Kohli, MD, PhD | Investigating the enzymatic basis for diversity generation in the immune system and pathogens; enzyme mechanisms, chemical biology, protein evolution

Mitchell Lewis, DPhil | Gene regulation; protein crystallography; structural basis of recognition

Kathy Fange Liu, PhD

Kristen W. Lynch, PhD | Mechanism and consequences of regulated alternative splicing

Ronen Marmorstein, PhD | X-ray crystallography, chromatin regulation, tumor suppressors, oncoproteins, kinases, aging, structure-based inhibitor design

Kenji Murakami, PhD | Transcription initiation and regulation in eukaryote Itzhak Nissim

Trevor M. Penning, PhD | Structure-function of aldo-keto reductases; role in steroid hormone action and chemical carcinogenesis

E. James Petersson, PhD

Mark. A. Sellmyer, MD, PhD | Molecular tools for cancer, infection, and immunology

Kim A. Sharp, PhD | Graduate Group Chair, Theory of protein and nucleic acid structure and function

James Shorter, PhD | Regulation of beneficial or neuropathogenic prions and amyloids by protein-remodeling factors, molecular chaperones, and small molecules

Emmanuel Skordalakes, PhD | X-ray crystallography; telomere biology; cancer and aging

David W. Speicher, PhD | Cancer proteomics; structure-function of membrane associated proteins: protein chemistry and mass spectrometry

Cecilia Tommos, PhD | Protein radicals and electrochemistry; cation-x interactions; protein forced folding

Gregory D. Van Duyne, PhD | Structural biology; protein-protein interactions; x-ray crystallography

Sergei A. Vinogradov, PhD | Functional macromolecules, optical imaging probes, porphyrin chemistry, dendrimer chemistry, oxygen microscopy and tomography

A. Joshua Wand, PhD | Protein structure and dynamics; molecular recognition and signal transduction; NMR spectroscopy

Jeremy E. Wilusz, PhD | Regulation of noncoding RNA biogenesis and function

 

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