Posters

Poster session details

Poster Session 1: 7:30 – 8:30 p.m. (odd-numbered posters)
Poster Session 2: 8:30 – 9:30 p.m. (even-numbered posters)

* Poster presenter
Names of students eligible for poster prizes are underlined

  1. Williams, Laura A.* and Maya Capelson. Structural and functional studies of the leukemia-associated nucleoporin Nup98.
  2. Tuazon, Francesca* and Mary C. Mullins. Shaping the BMP signaling gradient through regulation of metalloprotease activity.
  3. Dimitrova, Valentina S.* and Zhe Lu. Structural and functional investigation of the polycystin-2 ion channel.
  4. Zhao, Zhenyu*, Christopher C. Moser and P. Leslie Dutton. Theoretical and practical examination of electron transfer based photochemical processes in proteins.
  5. Smoak, Evan M.*, Samantha J. Falk, Lucie Y. Guo, Nikolina Sekulic, Tomoyasu Mani, Glennis A. Logsdon, Kushol Gupta, Lars E. T. Jansen, Gregory D. Van Duyne, Sergei A. Vinogradov, Michael A. Lampson and Ben E. Black. CENP-C stabilizes CENP-A nucleosomes at the centromere.
  6. Berger, Bryan W.*, Lindsey Stretz, Elizabeth Weiler and Logan C. MacDonald. S. maltophilia: from nosocomial pathogen to nanoparticle biosynthesis.
  7. Falk, Samantha J.*, Evan M. Smoak*, Lucie Y. Guo, Nikolina Sekulic, Tomoyasu Mani, Glennis A. Logsdon, Kushol Gupta, Lars E. T. Jansen, Gregory D. Van Duyne, Sergei A. Vinogradov, Michael A. Lampson and Ben E. Black. Structural changes imparted to the CENP-A nucleosome upon CENP-C binding.
  8. Dawicki-McKenna, Jennine M.*, Marie-France Langelier, Jamie E. DeNizio, Amanda A. Riccio, Connie Cao, Kelly R. Karch, Michael McCauley, Ben E. Black and John M. Pascal. Poly(ADP-ribose) polymerase-1 (PARP-1) activity is regulated by a domain that locally unfolds when PARP-1 binds DNA damage.
  9. Karch, Kelly R.*, Barry M. Zee and Benjamin A. Garcia. High resolution is not a strict requirement for characterization and quantification of histone PTMs.
  10. Turegun, Bengi* and Roberto Dominguez. The role of Rtt102- and ATP-binding in regulating Arp7/9 structure and function.
  11. Zelent, Bogumil*, Anne Raimondo, Amy Barrett, Carol W. Buettger, Pan Chen, Anna L. Gloyn and Franz M. Matschinsky. Analysis of the cooperative interaction between the allosterically regulated proteins GK and GKRP using tryptophan fluorescence.
  12. Emptage, Ryan P.*, Mark. A. Lemmon and Kathryn M. Ferguson. Investigating KA1 domain-mediated regulation of MARK/PAR1 kinases.
  13. Zelent, Bogumil*, Nicolai M. Doliba and Franz M. Matschinsky. Glucokinase control of metabolic switches in pancreatic beta-cells and liver.
  14. Ugras, Scott E.*, Hua Ding, Chris McKennan, Perry Evans, Steven H. Seeholzer, Kelvin Luk, Virginia M-Y. Lee and Harry Ischiropoulos. Quantifying proteostatic changes caused by alpha synuclein aggregation.
  15. Doliba, Nicolai M.*, Qin Liu, Changhong Li, Pan Chen, Chengyang Liu, David Frederick, Jie Chen, Joseph A. Baur, Michael J. Bennett, Ali Naji and Franz M. Matschinsky. Interconnection between mitochondrial energy metabolism, calcium signaling, and insulin secretion in mouse and human pancreatic islets after chronic exposure to free fatty acids.
  16. Fuglestad, Brian*, Sabrina Bedard, Li Liang, Kathleen G. Valentine, Trevor M. Penning and A. Joshua Wand. Using reverse micelle encapsulation to improve fragment based drug discovery.
  17. Vanderkooi, Jane M.* The self assembly of snowflakes.
  18. Fuglestad, Brian*, Christine Jorge, Bryan S. Marques, Nathaniel V. Nucci, Evan S. O’Brien, Kathleen G. Valentine and A. Joshua Wand. Confined space, structural biology, biophysics and drug discovery.
  19. Mack, Korrie L.*, Meredith E. Jackrel, Jamie E. DeNizio and James Shorter. Ameliorating potentiated Hsp104 variants.
  20. Fry, Bryan A.*, Christopher C. Moser and P. Leslie Dutton. Designing protein maquettes for intermolecular electron transfer.
  21. Bonasio, Roberto*. Role of noncoding RNAs in chromatin biology and epigenetics.
  22. Wu, Neo* and Mark A. Lemmon. DWnt5 / Drl interactions.
  23. Jordan, E. Joseph* and Ravi Radhakrishnan. In silico methods to classify cancer driver mutations.
  24. Townsend, James P.* and Alison M. Sweeney. Evolving hydrogels: structure and evolution of ctenophore and cnidarian mesoglea.
  25. Guo, Lucie Y.*, Xing-Jun Cao, Ana Stankovic, Lars E.T. Jansen, Benjamin A. Garcia and Ben E. Black. Identification of Cdk-dependent phosphorylation sites on the CENP-A chromatin assembly complex by quantitative phosphoproteomics.
  26. Soo, Michael Y.* and James Shorter. Potentiated disaggregases rescue toxicity of diverse dosage-sensitive genes.
  27. Tarasovetc, Ekaterina V.* , Nikita B. Gudimchuk, Alexei L. Drobyshev, Benjamin Vitre, Vadim V. Mustyatsa, Don W. Cleveland, Fazoil I. Ataullakhanov and Ekaterina L. Grishchuk. Conformational properties of the moving kinesin probed with the Tethered Cargo Motion assay.
  28. DeBrosse, Catherine M.*, Shana E. McCormack, Ravi P. Nanga, Neil E. Wilson, Hari Hariharan, Kevin D'Aquilla and Ravinder Reddy. Creatine CEST imaging in mitochondrial disease patients.
  29. Mancini, Joshua A.*, Goutham Kodali, Aparna Nagarajan, Michelle Liberton, Jonathan Lindsey, Donald A. Bryant, Himadri B. Pakrasi, Christopher C. Moser and P. Leslie Dutton. Biogenesis of maquettes for light harvesting and energy transfer in vitro and in vivo.
  30. Higbee, Elizabeth M.*, Lesan Yan and Andrew Tsourkas. Synthesis of environmentally responsive materials for nanomedicine.
  31. Babiash, Eric S.*, Maura Jones and Gideon Dreyfuss. Minimal SMN complexes.
  32. Kubiak, Jeffrey M.* and Rahul M. Kohli. The impact of modulating LexA cleavage on SOS pathway mutagenesis.
  33. Ricketts, M. Daniel*, Taranjit Singh Rai, Brian Frederick, Henry Hoff, Yong Tang, David C. Schultz, Peter D. Adams and Ronen Marmorstein. Ubinuclein-1 confers histone H3.3-specific binding specificity by the HIRA histone chaperone complex.
  34. Shroder, Deborah Y.*, Yujie Sun, Osamu Sato, Mitsuo Ikebe and Yale E. Goldman. Myosin XI: the family speed demon.
  35. Yee, Keolamau*, Meredith E. Jackrel, Amber Tariq and James Shorter. Engineering Hsp104 variants to reduce TDP-43 toxicity.
  36. Akl, Adam*, Xiaowei Xu, Ravi Amaravadi and David W. Speicher. Identification of secreted proteins that reflect autophagy dynamics in melanoma.
  37. Yarosh, Christopher A.*, James Lipchock, Jinsong Qiu, Xiang-Dong Fu and Kristen W. Lynch. Dissecting protein-protein interactions that regulate PSF RNA-binding capacity.
  38. Rivera-Santiago, Roland F.*, Sandra Harper, Sira Sriswasdi and David W. Speicher. Determining structures of proteins and protein complexes using zero-length chemical crosslinking and mass spectrometry (CX-MS).
  39. Bialas, Christopher P.*, Lauren Jarocha, Goutham Kodali, Peter Hore, Christopher C. Moser and P. Leslie Dutton. Magnettoquettes: maquettes as a model for magnetic sensing.
  40. Logsdon, Glennis A.*, Emily A. Bassett, Jamie E. DeNizio, Evelyne Barrey, Patrick Heun and Ben E. Black. Determinants of CENP-A for early steps in centromere establishment.
  41. Crescenzi, Rachelle*, Catherine M. DeBrosse, Ravi P. Reddy, Kevin D'Aquilla, Leonard Nettey, Hari Nath, Michiyo Iba, Hari Hariharan, Virginia M.-Y. Lee and Ravinder Reddy. Longitudinal neurophysiologic changes in tauopathy mice.
  42. Tariq, Amber*, Meredith E. Jackrel, Keolamau Yee and James Shorter. Engineering the NBD1 domain of Hsp104 to suppress toxicity in yeast.
  43. Lippert, Lisa G.*, Tali Dadosh, Benjamin T. Diroll, Jeffrey Hallock, Christopher B. Murray, Samara L. Reck-Peterson and Yale E. Goldman. Cytoplasmic dynein ring tilting, identified using combined single particle tracking and PolTIRF, correlates with stepping.
  44. Marques, Bryan S.*, Christine Jorge, Nathaniel V. Nucci, Bertrand E. Garcia-Moreno and A. Joshua Wand. Site-resolved measurements of protein hydration dynamics
  45. Liu, Monica Y.*, Daniel J. Crawford and Rahul M. Kohli. Biochemical regulation and genomic targeting of TET-catalyzed cytosine oxidation.
  46. Sharp, Kim A.* The remarkable hydration of the antifreeze protein maxi: a computational study.
  47. Esipova, Tatiana V.* and Sergei A. Vinogradov. Increasing of two-photon absorption cross-section in tetrapyrroles.
  48. Schutsky, Emily K.* and Rahul M. Kohli. Defining and exploiting APOBEC3A's cytidine deaminase activity against the extended epigenome.
  49. Jackrel, Meredith E.*, Morgan E. DeSantis, Bryan A. Martinez, Laura M. Castellano, Rachel M. Stewart, Kim A. Caldwell, Guy A. Caldwell and James Shorter. Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events.
  50. Stetz, Matthew A.*, Marie V. Carter, Kathleen G. Valentine and A. Joshua Wand. Chemical shift assignment of the lac repressor protein.
  51. Woody, Michael S.*, Marco Capitanio, E. Michael Ostap and Yale E. Goldman. Detection of ultrafast mechanical transitions in β-cardiac myosin using high-speed optical trapping.
  52. Remsberg, Jarrett R.*, Sean Armour, Zheng Sun, Simone Sidoli, Benjamin A. Garcia and Mitchell A. Lazar. Characterization of nuclear receptor complexes in vivo by ChAIN-MS.
  53. Mo, Charlie Y.*, Mark Goulian and Rahul M. Kohli. Genetic and small molecule efforts to modulate the SOS pathway and bacterial mutation.
  54. Ahmed, Ismail A.*, Ileana M. Pazos, Mariana I. León Berríos and Feng Gai. Using p-cyanophenylalanine as a pH sensor to determine N-terminal pK values of peptides and membrane-penetrating kinetics of cell-penetrating peptides.
  55. Boetefuer, Erica L.*, Mariel Coradin and Hua-Ying Fan. CSB becomes enriched within the nucleolus upon oxidative stress to regulate chromatin structure.
  56. Li, Huiguang*, Kay Perry, Kushol Gupta, Young Hwang, Frederic D. Bushman and Gregory D. Van Duyne. Crystal structure of poxvirus resolvase.
  57. O'Brien, Evan S.*, Nathaniel V. Nucci, Brian Fuglestad, Kathleen G. Valentine and A. Joshua Wand. The beginning of the end: cardiolipin, cytochrome c and the apoptotic trigger.
  58. Valentine, Kathleen G.*, Phillip Lottman, Christian Griesinger and A. Joshua Wand. Faster than a speeding bullet: shuttle DNP of a protein in a reverse micelle.
  59. Walters, Christopher R.*, Solongo Batjargal, Anne M. Wagner and E. James Petersson. Efficient methods in production of unnatural amino acid containing proteins.
  60. Cole, Brian S.*, Ganesh Shankarling and Kristen W. Lynch. Integrative analysis of hnRNP L-regulated mRNA splicing and expression in T cells.
  61. Ricciuti, Alec J.*, Benjamin T. Walters, Elizabeth A. Sweeny, Morgan E. DeSantis, Ian Dunn, Zhongyuan Kan, Leland Mayne, James Shorter and S. Walter Englander. Hsp104 quaternary structure, nucleotide binding energetics, and homology model refinement via HDX-MS
  62. Magin, Robert S.*, Glen Liszczak and Ronen Marmorstein. The molecular basis for Histone H4- and H2A-Specific Amino-Terminal Acetylation by NatD.
  63. Castellano, Laura M.* and James Shorter. Harnessing Hsp104 to antagonize seminal amyloid and counter HIV infection.
  64. Howard, Kathleen P.*, Bryan Green, Shenstone Huang and Shawn Kim. Site-directed spin-label EPR spectroscopy of influenza A M2 protein.
  65. Ford, Alice F.*, Lin Guo, Emily A. Scarborough and James Shorter. Molecular mechanisms of hnRNPA1 and hnRNPA2 misfolding and toxicity.
  66. Gay-Antaki, Carlos* and John H. Wolfe. Improved delivery of a therapeutic protein in the mouse CNS by fusion with tetanus toxin fragment C.
  67. Bagchi, Atrish*, Nicholas J. Bessman, Zhongyuan Kan, S. Walter Englander, Mark A. Lemmon and Kathryn M. Ferguson. Dynamic regulation and dysregulation of the epidermal growth factor receptor.
  68. Lim, Jackwee*, Vignesh Kasinath and A. Joshua Wand. Conformational entropy can provide access to high affinity interactions by proteins.
  69. Fernandez, Meilin M.*, Abdenour Soufi and Kenneth S. Zaret. Reconstitution of interactions between nucleosomes and reprogramming transcription factors in vitro.
  70. Harpole, Kyle W.*, Senthil Ganesan, Wolfgang Peti and A. Joshua Wand. Probing the role of conformational entropy in protein-inhibitor binding.
  71. Song, Shufei*, Jesse Platt and F. Bradley Johnson. The role of Rap1 in yeast senescence and gene transcription regulation.
  72. Eskici, Gözde* and Paul H. Axelsen. Amyloid fibril nucleation in reverse micelles.
  73. Wang, Yanxin J.*, Anne M. Wagner and E. James Petersson. Towards semi-synthesis of selenocysteine containing proteins.
  74. Carey, Jeffrey N.*, Manuela Roggiani and Mark Goulian. Molecular basis of highly variable aerobic expression of TMAO metabolism genes in Escherichia coli.
  75. Chen, Xing*, Jacob M. Goldberg and E. James Petersson. Thioamide peptide in protease studies.
  76. Ajith, Sandya* and Kristen W. Lynch. Investigating the mechanisms by which CELF2 regulates LEF1 alternative splicing.
  77. Ohnishi, Tomoko*, S. Tsuyoshi Ohnishi and John C. Salerno. Role of protein-associated quinones QNf and QNs in complex I energy coupling.
  78. Jamiolkowski, Ryan M.*, Chunlai Chen, Barry S. Cooperman and Yale E. Goldman. Comparison of ribosomal PRE state while stalled and during active translocation using single molecule FRET
  79. Rice, Cory T.* and Emmanuel Skordalakes. Structural studies of human CTC1.
  80. Speer, Kelsey F.*, Jeannine M. Mendrola, Peter S. Klein and Mark A. Lemmon. Understanding the interaction of Wnt ligands with their cell surface receptors.
  81. Yuan, Zuo-Fei*, Shu Lin and Benjamin A. Garcia. Quantification of histone post-translational modifications by mass spectrometry.
  82. Wein, Samuel P.*, Simone Sidoli and Benjamin A. Garcia. Mass spectrometry of small RNAs.
  83. Lin Shiao, Enrique*, Matthias G. J. Baud, Teresa Cardote, Cynthia Tallant, Annica Pschibul, Kwok-Ho Chan, Michael Zengerle, Jordi R. Garcia, Terence T.-L. Kwan, Fleur M. Ferguson and Alessio Ciulli. A bump-and-hole approach for BET bromodomain function elucidation.

  • Posters will be assigned to Poster Session 1 (odd-numbered posters - 7:30 - 8:30 p.m.) or Poster Session 2 (even-numbered posters - 8:30 - 9:30 p.m.), during which time you are expected to stay with your poster.
  • Easels, poster boards (40" X 60"), and push pins will be provided on site.  Posters can be set up at any time, but should be in place before dinner Thursday (dinner is at 6:30 p.m.), and remain in place both days of the retreat.  
  • Posters must be removed by 1:00 p.m. on Friday.  Pushpins should be returned to the registration table. Please make sure that no pushpins are on the floor in your area and do not leave any pushpins on the poster boards.  Easels and poster boards can remain in place.
  • Posters submitted by a graduate student as first author and affiliated with B&B and BMB labs are eligible for cash prizes funded by the Department of Biochemistry and Biophysics and the Dr. George W. Raiziss Education Fund.  
  • Faculty attending the retreat will be judging the student posters.  Ballots for the poster judging must be completed and returned to the registration table by 10:00 p.m. on Thursday.
  • Poster awards will be announced at the beginning of Session 4 on Friday.

The Retreat is open to the pubic. Therefore, posters or presentations given at this even are public disclosures and may negatively impact on the University of Pennsylvania’s ability to protect the work under intellectual property law. If you feel the work may be of commercial interest or plan to disclose it to Penn’s Center for Technology Transfer in the future, CTT encourages you to disclose it to their office at least one month prior to the event.