Department of Biochemistry and Biophysics

and the Graduate Group in Biochemistry and Molecular Biophysics

Thursday, November 7, 2013

7:30 A.M.

Bus arrival (outside Stellar-Chance Labs on Curie Boulevard)

8:00 A.M.

Bus departure from Penn

10:30 A.M.

Bus arrival at Skytop Lodge
Note:  Check-in is at 4 p.m., but rooms may be available earlier

11:00 A.M. – 12:30 P.M.

Buffet Lunch (South Windsor Dining Room) 

Session I Evergreen Ballroom

Discussion Leader:  Mark A. Lemmon, Ph.D.

12:30 – 1:00 P.M.

Mark A. Lemmon, Ph.D.
George W. Raiziss Professor in Biochemistry and Biophysics
Diversity in receptor tyrosine kinase activation mechanisms”

1:00 – 1:20 P.M.

Edward R. Ballister
Graduate student (laboratory of Michael A. Lampson, Ph.D.)
“Right place, wrong time: recruitment of Mad1 to kinetochores after metaphase reactivates the spindle assembly checkpoint”

1:20 – 1:50 P.M.

Roland L. Dunbrack, Jr., Ph.D.
Adjunct Professor of Biochemistry and Biophysics
“Computational design of antibodies”

1:50 – 2:10 P.M.

Yu-San Huoh
Graduate student (laboratory of Kathryn M. Ferguson, Ph.D.)
“Pellino E3-ubiquitin ligases recognize specific phosphothreonine-peptide sequences and have distinct substrate specificities” 

2:10 – 2:30 P.M.

Byung Ran So, Ph.D.
Research Associate (laboratory of Gideon Dreyfuss, Ph.D.)
“How cells produce over-abundance of U1 snRNP: a key component in protection and processing of the nascent transcriptome”

2:30 – 4:00 P.M.

Free Time (poster setup in Hemlock Ballroom)

Session 2 • Evergreen Ballroom

Discussion Leader:  Gregory D. Van Duyne, Ph.D.

4:00 – 4:30 P.M.

S. Walter Englander, Ph.D.
Professor of Biochemistry and Biophysics
Protein structure-function studies by HX MS”

4:30 – 4:50 P.M.               

David R. Slochower
Graduate student (laboratory of Paul A. Janmey, Ph.D.)
“Simulations of PtdInsP2

4:50 – 5:20 P.M.               

J.  Alan Diehl, Ph.D.
J. Samuel Staub, M.D. Endowed Professor
Department of Cancer Biology
“miR-211 is a pro-survival micro-RNA that regulates chop expression in a PERK-dependent manner”

5:20 – 5:40 P.M.

Meredith E. Jackrel, Ph.D.
Postdoctoral Fellow (laboratory of Jim Shorter, Ph.D.)
“Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events”

5:40 – 6:00 P.M.

Kathleen S. Molnar
Graduate student (laboratory of William F. DeGrado, Ph.D.)
Proteomic profiling of platelets"

6:00 – 7:30 P.M.

Buffet Dinner (South Windsor Dining Room)

7:30 – 9:30 P.M.

Poster Session and Reception (Hemlock Ballroom)

Friday, November 8, 2013

7:30 – 9:00 A.M.

Buffet Breakfast (South Windsor Dining Room)

Session 3 Evergreen Ballroom

Discussion Leader:  Kathryn M. Ferguson, Ph.D.

9:00 – 9:30 A.M.

Ben E. Black, Ph.D.
Associate Professor of Biochemistry and Biophysics
The nucleosome at the foundation of the kinetochore"

9:30 – 9:50 A.M.

Nicholas J. Bessman
Graduate student (laboratory of Mark A. Lemmon, Ph.D.)
Ligand activation of EGF receptor

9:50 – 10:20 A.M.

Sergei A. Vinogradov, Ph.D.
Associate Professor of Biochemistry and Biophysics
"Exploring new approaches in optical imaging"

10:20 – 10:40 A.M.

Nataline D. Meinhardt
Graduate student (laboratory of Doron C. Greenbaum, Ph.D.)
Design of small, a-helical protease inhibitors and probes”

10:40 – 10:50 A.M.

Presentation of Poster Awards

10:50 – 11:00 A.M.

Group Photograph

11:30 A.M. – 1:00 P.M.

Buffet Lunch (South Windsor Dining Room)
Poster Breakdown / Check-out
(Note: Check-out time is 1:00 p.m.)

Session 4 Evergreen Ballroom

Discussion Leader:  Kristen W. Lynch, Ph.D.

1:00 – 1:20 P.M.

P. LESLIE DUTTON AWARD TALK

Morgan E. DeSantis, Ph.D.
Postdoctoral Fellow (former graduate student in the laboratory of Jim Shorter, Ph.D.; currently in laboratory of Samara Reck-Peterson, Ph.D., Harvard University)
Inter-subunit coordination in Hsp104”

1:20 – 1:50 P.M.

John I. Murray, Ph.D.
Assistant Professor of Genetics
“Combinatorial regulation of development by lineage-specific transcription factors"

1:50 – 2:10 P.M.

Benjamin T. Walters
Graduate student (laboratory of S. Walter Englander, Ph.D.)
What took you so long? Slow folding in a multi-domain protein studied by HX MS”

2:10 – 2:30 P.M. 

Kushol Gupta, Ph.D.
Research Associate (laboratory of Gregory D. Van Duyne, Ph.D.)
“The application of small-angle X-ray and neutron scattering to the study of large nucleoprotein assemblies”

2:30 – 3:00 P.M.

Kristen W. Lynch, Ph.D.
Associate Professor of Biochemistry and Biophysics
Molecular rearrangements that control pre-mRNA splicing”

3:30 P.M.                               

Bus Arrival at Skytop Lodge

4:00 P.M.                              

Bus Departure for Penn

~6:30 P.M.

Bus Arrival at Penn