Thursday, November 12, 2015

7:30 A.M.

Bus arrival (outside Stellar-Chance Labs on Curie Boulevard)

8:00 A.M.

Bus departure from Penn

~10:30 A.M.

Bus arrival at Skytop Lodge

10:30 A.M. – 12:00 NOON

Free Time

Registration/pick-up of room keys
(Rooms available for occupancy after 4:00 p.m.)

Poster set-up in Evergreen Ballroom

12:00 NOON – 1:00 P.M.

South Windsor Dining Room

SESSION 1 – Hemlock Ballroom

Discussion leader: Kristen W. Lynch, Ph.D.

1:00 – 1:15 P.M.

Elizabeth Rhoades, Ph.D.
Associate Professor of Chemistry
Order from disorder - determining functions of dysfunctional proteins

1:20 – 1:35 P.M.

Scott E. Ugras
Graduate student (laboratory of Harry Ischiropoulos, Ph.D.)
Quantitative proteomics reveals proteostatic changes driven by alpha synuclein aggregation

1:40 – 1:55 P.M.

Manas Chakraborty, Ph.D.
Postdoctoral fellow (laboratory of Ekaterina L. Grishchuk, Ph.D.)
Minimal molecular system to reconstitute a Microtubule wall-to-end transition in vitro

2:00 – 2:15 P.M.

Roberto Bonasio, Ph.D.
Assistant Professor of Cell & Developmental Biology
RNA-mediated regulation of chromatin proteins

2:20 – 2:35 P.M.

Christopher P. Bialas
Graduate student (laboratory of P. Leslie Dutton, Ph.D.)
Magentomaquettes: Man-designed magnetosensing proteins as a model for cryptochrome function

2:40 - 4:45 P.M.

Free Time

SESSION 2 - Hemlock Ballroom

Discussion leader: Ben E. Black, Ph.D.

4:45 – 5:10 P.M.


Lucie Y. Guo (laboratory of Ben E. Black, Ph.D.)
CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere
Evan M. Smoak (laboratory of Ben E. Black, Ph.D.)
Transgenerational inheritance of centromere identity in the mammalian oocyte

5:15 – 5:30 P.M.

David W. Speicher, Ph.D.
Wistar Institute Professor of Biochemistry & Biophysics
Probing structures and conformational changes of large protein complexes using structural mass spectrometry

5:35 – 5:50 P.M.

Bengi Turegun
Graduate student (laboratory of Roberto Dominguez, Ph.D.)
Actin-related proteins in the nucleus and their role in chromatin remodeling

5:55 – 6:10 P.M

Arjun Raj, Ph.D.
Assistant Professor of Bioengineering
Transcriptional heterogeneity and therapeutic resistance in cancer

6:30– 7:30 P.M.

South Windsor Dining Room

7:30 – 9:30 P.M.

Poster Session & Reception
Evergreen Ballroom

Friday, November 13, 2015

7:30 - 9:00 A.M.

South Windsor Dining Room

9:00 - 10:00 A.M.

Free Time

Poster breakdown by 1:00 P.M.

Checkout by 1:00 P.M.

SESSION 3 – Hemlock Ballroom

Discussion leader: Hua-Ying Fan, Ph.D.

10:00 - 10:15 A.M.

E. Michael Ostap, Ph.D.
Professor of Physiology
Structural determinants of myosin mechanosensing

10:20 - 10:35 A.M.

Lin Guo, Ph.D.
Postdoctoral fellow (laboratory of James Shorter, Ph.D.)
Defining Kapβ2 as a protein disaggregase for ALS disease protein: FUS

10:40 – 10:55 A.M.

Matthew A. Stetz
Graduate student (laboratory of A. Joshua Wand, Ph.D.)
Revisiting allostery in the lac repressor protein

11:00 - 11:15 A.M.

Tobias Baumgart, Ph.D.
Associate Professor of Chemistry, and Chemical & Biomolecular Engineering
Mechanisms of membrane shaping by peripheral proteins

11:20 - 11:35 A.M.

Charlie Y. Mo
Graduate student (laboratory of Rahul M. Kohli, M.D., Ph.D.)
Tuning activation of the SOS regulator LexA modulates bacterial evolution under antibiotic stress

11:45 A.M.- 12:00 NOON

Group Photograph

12:00 NOON - 1:00 P.M.

South Windsor Dining Room

SESSION 4 – Hemlock Ballroom

Discussion leader: Rahul Kohli, M.D., Ph.D.

1:00 -1:15 P.M.

Presentation of Poster Awards

1:15 - 1:30 P.M.

Luca Busino, Ph.D.
Assistant Professor of Cancer Biology
Cullin-Ring-Ubiquitin ligases (CRLs): Molecular mechanisms and biological relevance in cell proliferation

1:35 - 1:50 P.M.

Robert S. Magin
Graduate student (laboratory of Ronen Marmorstein, Ph.D.)
The molecular basis of ribosome-associated N-terminal acetylation by NatA

1:55 – 2:10 P.M.

Paul H. Axelsen, M.D.
Professor of Pharmacology and Biochemistry & Biophysics
Polymorphic infectious protein structures

2:15 - 2:30 P.M.

Jarrett R. Remsberg
Graduate student (laboratory of Mitchell A. Lazar, M.D., Ph.D.)
The role of histone deacetylase 3 in metabolism

2:35 - 2:50 P.M.

Simone Sidoli, Ph.D.
Postdoctoral Fellow (laboratory of Benjamin A. Garcia, Ph.D.)
Introducing epigenomics in systems biology: cross-talk between cell signal transduction and epigenetic mechanisms

3:15 P.M.

Bus arrival at Skytop Lodge

3:30 P.M.

Bus departure for Penn

~6:30 P.M.

Bus arrival at Penn


The Retreat is open to the public. Therefore, posters or presentations given at this event are public disclosures and may negatively impact on the University of Pennsylvania’s ability to protect the work under intellectual property law. If you feel the work may be of commercial interest or plan to disclose it to Penn’s Center for Technology Transfer in the future, CTT encourages you to disclose it to their office at least one month prior to the event.