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Winter 2014

All seminars are Fridays at 4:00 p.m.
JF Library, 248 Antatomy-Chemistry Building
Refreshments served at 3:45 p.m.

Modeling

JANUARY 9
Kim Sharp, Evan O'Brien
Laboratory of Kim Sharp | Biochemistry & Biophysics
Why we are obsessed with entropy: The origin of high affinity protein-ligand binding

JANUARY 16
Alison Sweeney, James Townsend, Tom Dodson
Laboratory of Alison Sweeney | Physics & Astronomy
Multi-scale molecular modeling: generating physical insights when experiments are hard or impossible

JANUARY 23
Paul Axelsen, Gözde Eskici
Laboratory of Paul Axelsen | Systems Pharmacology & Translational Therapeutics
Is the amyloid fibril good, bad, or just ugly?

JANUARY 30
Les Dutton, Josh Mancini, Zhenyu Zhou, Bryan Fry
Laboratory of Les Dutton | Biochemistry & Biophysics
Sunshine to Moonshine: manmade proteins for solar fuel

Past Topics and Seminars, Fall 2014

PROTEIN COMPLEXES AND THEIR FUNCTION - CLICK FOR COMPLETE LISTINGS

SEPTEMBER 19
Eric Babiash, Anna Maria Pinto
Laboratory of Gideon Dreyfuss | Biochemistry & Biophysics
Function and biogenesis of U1 snRNP: an overarching mRNA regulator

SEPTEMBER 26
Scott Ugras
Laboratory of Harry Ischiropoulos | Pediatrics
Alpha synuclein aggregation perturbs phosphorylation signaling

OCTOBER 3
Cory Rice
Laboratory of Emmanuel Skordalakes | Gene Expression and Regulation Program, Wistar Institute
CST dependent telomere length regulation

OCTOBER 10
Alec Ricciuti, Wenbing Hu
Laboratory of Walter Englander | Biochemistry & Biophysics
Protein interactions studied by HX MS (hydrogen exchange and mass spectrometry)

OCTOBER 17
Matt Stetz, Kyle Harpole
Laboratory of Josh Wand | Biochemistry & Biophysics
Proteins, conformational entropy and the magical complexity of allostery

OCTOBER 24
Robert Magin, Allison Haigney
Laboratory of Ronen Marmorstein | Biochemistry & Biophysics
Protein complexes and their function in protein acetylation

OCTOBER 31
Glennis Logsdon, Samantha Falk
Laboratory of Ben Black | Biochemistry & Biophysics
The CENP-A nucleosome, the proteins that bind to it, and the mechanisms of centromere establishment and maintenance

MODELING - CLICK FOR COMPLETE LISTINGS

NOVEMBER 7
David Speicher, Roland Rivera-Santiago
Laboratory of David Speicher | The Wistar Institute
Structural mass spectrometry using zero-length crosslinks

DECEMBER 5
Ravi Radhakrihnan (intro), Joe Jordan, Ryan Bradley , RIchard Tourdot
Laboratory of Ravi Radhakrishnan | Bioengineering
Minimal models across multiple scales – from proteins to cells – mechanisms, constraints, and predictive power

DECEMBER 12
Les Dutton (intro), Nate Ennist, Chris Bialas
Laboratory of Les Dutton | Biochemistry and Biophysics
Modeling solar-activated charge-separation in bird navigation and photosynthesis

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