PENN MEDICINE |
SCHOOL OF ARTS AND SCIENCES PENN ENGINEERING |
Department of Biochemistry & Biophysics
Ben E. Black, Ph.D. Chromosome segregation; chromatin structure; epigenetic centromere specification; hydrogen/deuterium exchange
Bohdana M. Discher, Ph.D. Designing and interfacing proteins with membranes and electronic devices
Gideon Dreyfuss, Ph.D. Nuclear transport, hnRNP complexes, RNA-binding proteins, spinal muscular atrophy
P. Leslie Dutton, Ph.D. Oxido-reductase engineering; design and chemical synthesis of redox proteins
S. Walter Englander, Ph.D. Protein folding; structure, structure change, and dynamics; H-exchange; NMR
Hua-Ying Fan, Ph.D. Regulation of chromatin structure and its impact on human diseases
Benjamin A. Garcia, Ph.D. Quantitative propeomics for understanding signaling pathways.
Roland G. Kallen, M.D., Ph.D. Structure, function, and regulation of expression of ion channels
Mark A. Lemmon, Ph.D. Biochemistry/biophysics of intermolecular interactions of growth factor receptor signaling
Mitchell Lewis, D.Phil. Gene regulation; protein crystallography; Structural basis of recognition
Paul A. Liebman, M.D. G-protein-receptor-arrestin mechanisms; visual signal transduction.
Kristen W. Lynch, Ph.D. Mechanism and consequences of regulated alternative splicing
Hillary C.M. Nelson, Ph.D.,MPH Structural biology; transcription; protein-DNA interactions; heat shock response
Kim A. Sharp, Ph.D. Theory of protein and nucleic acid structure and function
James Shorter, Ph.D. Regulation of beneficial or neuropathogenic prions and amyloids by protein-remodeling factors, molecular chaperones, and small molecules
Cecilia Tommos, Ph.D. Protein radicals and electrochemistry; cation-x interactions; protein forced folding
Gregory D. Van Duyne, Ph.D. Structural biology; protein-protein interactions; x-ray crystallography
Sergei A. Vinogradov, Ph.D. Functional macromolecules, optical imaging probes, porphyrin chemistry, dendrimer chemistry, oxygen microscopy and tomography
A. Joshua Wand, Ph.D. Protein structure and dynamics; molecular recognition and signal transduction; NMR spectroscopy
David F. Wilson, Ph.D. Integration of metabolism; oxidative phosphorylation; neuroregulation
Department of Cancer Biology
Lewis A. Chodosh, M.D., Ph.D. Mouse models, cancer, oncogenes, targeted therapy, development, genomics, computational biology, stem cells, imaging
J. Alan Diehl, Ph.D. Aspects of signal transduction, cell division and metabolism as they pertain to cancer biology.
Kathryn E. Wellen, Ph.D., Cancer cell metabolism, nutrient sensing
Xiaolu Yang, Ph.D. Molecular mechanisms of apoptosis and how they may relate to cancer and other diseases.
Department of Cell & Developmental Biology
Shelley L. Berger, Ph.D. Role of adaptors in regulation of transcriptional activation in yeast and humans
Phong Tran, Ph.D. Cytoskeleton organization and cellular pattern formation
John W. Weisel, Ph.D. Structural studies of molecular/cellular mechanisms in blood clotting and fibrinolysis
Department of Genetics
John I. Murray, Ph.D., Embryonic transcriptional regulation; fate specification; cell lineages; C. elegans; microscopy
Department of Medicine
Charles S, Abrams, M.D. Phospholipid signaling in platelets & lymphocytes
Joel S. Bennett, M.D. Regulation of integrin function
Morris J. Birnbaum, M.D., Ph.D. Regulation of cellular and organismal metabolism, insulin action
Lawrence Brass, M.D., Ph.D. Molecular basis for intracellular signaling in vascular biology
Rahul M. Kohli, M.D., Ph.D. Investigating the enzymatic basis for diversity generation in the immune system and pathogens; enzyme mechanisms, chemical biology, protein evolution
Harvey Rubin, M.D., Ph.D. Pathogenesis of dormancy in mycobacterium tuberculosis; biomolecular computation and enzymology and cell biology of serine proteases and serine protease inhibitors
Department of Microbiology
Sara Cherry, Ph.D. Viral-host interactions and innate immunity
Department of Pathology & Laboratory Medicine
Yair Argon, Ph.D. Quality control of protein folding in the cell by molecular chaperones
Virginia M.-Y. Lee, Ph.D. Pathobiology of Alzheimer's and Parkinson's disease
Michael S. Marks, Ph.D. Molecular mechanisms of intracellular protein transport and organelle biogenesis
X. Long Zheng, M.D., Ph.D. ADAMTS13 metalloprotease and microvascular thrombosis
Department of Pediatrics
Harry Ischiropoulos, Ph.D. Biological chemistry of nitric oxide; oxidative processes, protein aggregation and neurodegeneration
Department of Pharmacology
Paul H. Axelsen, M.D. Biophysical studies of molecular recognition and rational drug design
Scott Diamond, Ph.D. Mechanobiology, gene transfer, blood systems biology, drug discovery, protease chemical-biology
Doron Greenbaum, Ph.D. Protease function, chemical biology, proteomics, biochemistry, cell biology, malaria
Trevor M. Penning, Ph.D. Structure-function and gene regulation of the aldo-keto reductase superfamily
Department of Physiology
Joseph A. Baur, Ph.D. Molecular mechanisms of aging and caloric restriction
Roberto Dominguez, Ph.D. Actin cytoskeleton, protein phosphatase 1, structural biology
Kathryn M. Ferguson, Ph.D. Structural biology, growth factor receptor signaling, molecular mechanisms of protein-protein interactions
Ekaterina Grishchuk, Ph.D., Mechanisms that drive and control chromosome motions in mitosis
Yale E. Goldman, M.D., Ph.D. Motor proteins studied by photochemistry and spectroscopy
Paul Janmey, Ph.D. Cytoskeleton, biopolymer mechanics, phosphoinositides
Todd Lamitina, Ph.D. Cellular osmoregulation, stress-induced gene expression, C. elegans genetics
Zhe Lu, M.D., Ph.D. Structure-function relationship of ion channels; molecular mechanisms of protein-protein interactions
E. Michael Ostap, Ph.D. Biochemistry of contractile proteins, biophysics of cell motility, and characterization of unconventional myosins
Brian M. Salzberg, Ph.D. Multiple-site optical recording; excitation-secretion coupling; neural networks
Department of Radiation Oncology
Theresa Busch, Ph.D. Photodynamic therapy, tumor microenvironment
Department of Radiology
Jerry Glickson, Ph.D. Molecular imaging: NMR specroscopy and imaging of cancer; optical imaging of cancer; nanotechnology
Ravinder Reddy, Ph.D. Sodium and oxygen-17 MR methods; multiple quantum and polarization transfer MR techniques
Felix W. Wehrli, Ph.D. MRI of biomaterials microstructure, mathematical modeling, image processing
Department of Biology
Fevzi Daldal, Ph.D. Genetics, structure-function, regulation and biogenesis of cytochromes
Mark Goulian, Ph.D. Two-component signaling, bacterial regulatory circuits
Michael Lampson, Ph.D., Chromosome segregation in mitosis and meiosis, biosensors for mitotic kinases
Department of Chemistry
Tobias Baumgart, Ph.D. Biomembrane function: thermodynamics, dynamics and mechanics
Feng Gai, Ph.D. Spectroscopic study of protein folding/missfolding
E. James Petersson, Ph.D.,Semi-synthesis of labeled proteins to probe and control conformation
Jeffery G. Saven, Ph.D. Theory, simulation and design of proteins and folding molecules
Department of Bioengineering
Ravi Radhakrishnan, Ph.D., Computational structural biology and systems biology; cell membrane mediated trafficking; targeted drug delivery; cancer signaling
Arjun Raj, Ph.D., Systems biology; developmental biology; non-coding RNA
Casim A. Sarkar, Ph.D. Protein engineering; synthetic biology; cell-fate decisions
Chemical and Biomolecular Engineering
Scott L. Diamond, Ph.D., Mechanobiology, gene transfer, blood systems biology, drug discovery, protease chemical-boiology
Matthew Lazzara, Ph.D., ErbB-mediated cell signaling
Kathleen Boesze-Battaglia, Ph.D. Tetraspanin protein structure and role in degenerative disease processes
John H. Wolfe, V.M.D., Ph.D. Glycoproteins; lysosomal enzymes; storage diseases; gene transfer into brain
Ronen Marmorstein, Ph.D. Crystallography; biochemistry; transcription; cell-cycle; cancer
Emmanuel Skordalakes, Ph.D. X-ray crystallography; telomere biology; cancer and aging
David Speicher, Ph.D. Cancer proteomics; structure-function of membrane associated proteins: protein chemistry and mass spectrometry
Roland L. Dunbrack, Ph.D. Methods and applications of protein structure prediction
Heinrich Roder, Ph.D. NMR; protein folding mechanism; protein structure, dynamics and function