Eldridge Reeves Johnson University
Professor Emeritus of Biophysics

Ph.D., 1940, University of Pennsylvania
(Physical Chemistry)
Ph.D., 1942, Cambridge University
(Biology "B", Physiology)
D. Sc., 1952, Cambridge University

250 Anatomy Chemistry Building
Tel: 215-898-7159
Fax: 215-898-1806
Email: chance@mail.med.upenn.edu

Chance Departmental Page

 Our group's research focuses three areas:  1) cancer detection: angiogenesis, hypermetabolism and molecular beacons; 2) cognitive imaging: metabolic responses, hemodynamic response measured by NIR imaging; and 3) muscle function: oxygenation, blood volume in exercise; olympic athletes, geriatrics, and mitochondrial and vascular diseases.

 

Selected Publications:

Chen, Y., C. Mu, X, Intes and B. Chance (2001) Signal-to-noise analysis for detection sensitivity of small absorbing heterogeneity in turbid media with single-source and dual-interfering-source. Optics Express 9:212-224.

Szmedra, L., J. Im, S. Nioka, B. Chance and K.W. Rundell (2001) Hemoglobin/myoglobin oxygen desaturation during alpine skiing. Med. Sci. Sports Exerc. 33:232-236.

Chen, Y., S. Zhou, C. Xie, S. Nioka, M. Delivoria-Papadopoulos, E. Enday and B. Chance (2000) Preliminary evaluation of dual wavelength phased array imaging on neonatal brain function. J. Biomed. Optics 5:194-200.

 Chance, B., E. Anday, S. Nioka, S. Zhou, H. Long, K. Worden, C. Li, T. Turray, Y. Ovetsky, D. Pidikiti and R. Thomas (1998) A novel method for fast imaging of brain function, non-invasively, with light.  Optics Express 2:411-423.

 Chance, B., M. Cope, E. Gratton, N. Ramanujam and B. Tromberg (1998) Phase measurement of light absorption and scatter in human tissues. Rev. Sci. Instrum. 689:3457-3481.