Department of Biochemistry & Biophysics
Ben E. Black, Ph.D. Chromosome segregation; chromatin structure; epigenetic centromere specification; hydrogen/deuterium exchange
Britton Chance, Ph.D., Sc.D. Optical spectroscopy and imaging; photon migration in tissues; cancer studies
William F. DeGrado, Ph.D. Peptide and protein design
Gideon Dreyfuss, Ph.D. Nuclear transport, hnRNP complexes, RNA-binding proteins, spinal muscular atrophy
P. Leslie Dutton, Ph.D. Oxido-reductase engineering; design and chemical synthesis of redox proteins
S. Walter Englander, Ph.D. Protein folding; structure, structure change, and dynamics; H-exchange; NMR
Roland G. Kallen, M.D., Ph.D. Structure, function, and regulation of expression of ion channels
Mark A. Lemmon, Ph.D. Biochemistry/biophysics of intermolecular interactions of growth factor receptor signaling
Mitchell Lewis, D.Phil. Gene regulation; protein crystallography; Structural basis of recognition
Paul A. Liebman, M.D. G-protein-receptor-arrestin mechanisms; visual signal transduction.
Jeanne C. Myers, Ph.D. Structure-function of basement membrane zone collagens; connective tissue diseases
Hillary C.M. Nelson, Ph.D. Structural biology; transcription; protein-DNA interactions; heat shock response
Tomoko Ohnishi, Ph.D. Structure-function studies of respiratory components; biological EPR spectroscopy
Kim A. Sharp, Ph.D. Theory of protein and nucleic acid structure and function
James Shorter, Ph.D. Regulation of beneficial or neuropathogenic prions and amyloids by protein-remodeling factors, molecular chaperones, and small molecules
Cecilia Tommos, Ph.D. Protein radicals and electrochemistry; cation-π interactions; protein forced folding
Gregory D. Van Duyne, Ph.D. Structural biology; protein-protein interactions; x-ray crystallography
Jane M. Vanderkooi, Ph.D. Fluorescence; infrared; heme proteins
Sergei A. Vinogradov, Ph.D. Functional macromolecules, optical imaging probes, porphyrin chemistry, dendrimer chemistry, oxygen microscopy and tomography
A. Joshua Wand, Ph.D., Graduate Group Chair, Protein structure and dynamics; molecular recognition and signal transduction; NMR spectroscopy
David F. Wilson, Ph.D. Integration of metabolism; oxidative phosphorylation; neuroregulation
Takashi Yonetani, Ph.D. Structure, mechanism, and spectroscopy of hemoproteins and heme enzymes
Department of Radiology
Ari Borthakur, Ph.D. MRI techniques for clinical applications
Mark Elliott, Ph.D. fMRI and diffuse light imaging neuronal activity
Ravinder Reddy, Ph.D., Sodium and oxygen-17 MR methods; multiple quantum and polarization transfer MR techniques
Felix W. Wehrli, Ph.D. MRI of biomaterials microstructure, mathematical modeling, image processing
Department of Physiology
Roberto Dominguez, Ph.D. Actin cytoskeleton, protein phosphatase 1, structural biology
Kathryn M. Ferguson, Ph.D. Structural biology, growth factor receptor signaling, molecular mechanisms of protein-protein interactions
Yale E. Goldman, M.D., Ph.D. Motor proteins studied by photochemistry and spectroscopy
Todd Lamitina, Ph.D. Cellular osmoregulation, stress-induced gene expression, C. elegans genetics
Zhe Lu, M.D., Ph.D. Structure-function relationship of ion channels; molecular mechanisms of protein-protein interactions
E. Michael Ostap, Ph.D. Biochemistry of contractile proteins, biophysics of cell motility, and characterization of unconventional myosins
Brian M. Salzberg, Ph.D. Multiple-site optical recording; excitation-secretion coupling; neural networks
Department of Pharmacology
Paul H. Axelsen, M.D. Biophysical studies of molecular recognition and rational drug design
Doron Greenbaum, Ph.D. Protease function, chemical biology, proteomics, biochemistry, cell biology, malaria
Trevor M. Penning, Ph.D. Structure-function and gene regulation of the aldo-keto reductase superfamily
Wistar Institute
Shelley L. Berger, Ph.D. Role of adaptors in regulation of transcriptional activation in yeast and humans
Anthony J. Capobianco, Ph.D. Molecular aspects of Notch signaling; cancer
Ronen Marmorstein, Ph.D. Crystallography; biochemistry; transcription; cell-cycle; cancer
Emmanuel Skordalakes, Ph.D. X-ray crystallography; telomere biology; cancer and aging
David Speicher, Ph.D. Cancer proteomics; structure-function of membrane associated proteins: protein chemistry and mass spectrometry
Department of Bioengineering
John C. Schotland, M.D., Ph.D. Physical optics with applications to biomedical imaging
Department of Chemistry
Tobias Baumgart, Ph.D. Biomembrane function: thermodynamics, dynamics and mechanics
Barry S. Cooperman, Ph.D. Enzyme catalysis, regulation, ribosomes; kinetics; probes; bioorganic chemistry
Feng Gai, Ph.D. Spectroscopic study of protein folding/missfolding
Robin M. Hochstrasser, Ph.D. Photochemical and photobiological dynamics; nonlinear optical spectroscopy
Michael Klein, Ph.D. Computer simulation of lipid membranes, membrane proteins and ion channels
Jeffery G. Saven, Ph.D. Theory, simulation and design of proteins and folding molecules
Department of Pathology & Lab Medicine
Yair Argon, Ph.D. Quality control of protein folding in the cell by molecular chaperones
Virginia
M.-Y. Lee, Ph.D. Pathobiology of Alzheimer's and Parkinson's disease
Michael S. Marks, Ph.D. Molecular mechanisms of intracellular protein transport and organelle biogenesis
Bryan A. Wolf, M.D., Ph.D. Signal transduction in beta cells and neurons; diabetes; Alzheimer's disease
X. Long Zheng, M.D., Ph.D. ADAMTS13 metalloprotease and microvascular thrombosis
Department of Biology
Fevzi Daldal, Ph.D. Genetics, structure-function, regulation and biogenesis of cytochromes
Mark Goulian, Ph.D. Two-component signaling, bacterial regulatory circuits
Department of Cell & Developmental Biology
Christopher
Burd, Ph.D. Phosphatidylinositol signaling; Rab GTPase signaling
Phong Tran, Ph.D. Cytoskeleton organization and cellular pattern formation
John W. Weisel, Ph.D. Structural studies of molecular/cellular mechanisms in blood clotting and fibrinolysis
Department of Medicine
Charles S. Abrams, M.D., Phospholipid signaling pathways in platelets and lymphocytes
Joel S. Bennett, M.D. Regulation of integrin function
Lawrence Brass, M.D., Ph.D. Molecular basis for intracellular signaling in vascular biology
Wafik S. El-Deiry, M.D., Ph.D. Understanding and developing novel therapeutic strategies for cancer
Harvey Rubin, M.D., Ph.D. Pathogenesis of dormancy in mycobacterium tuberculosis; biomolecular computation and enzymology and cell biology of serine proteases and serine protease inhibitors
School of Veterinary Medicine
John H. Wolfe, V.M.D., Ph.D. Glycoproteins; lysosomal enzymes; storage diseases; gene transfer into brain
School of Dental Medicine
Kathleen Boesze-Battaglia, Ph.D. Tetraspanin protein structure and role in degenerative disease processes.
Fox Chase Cancer Center
Roland L. Dunbrack, Ph.D. Methods and applications of protein structure prediction
Heinrich Roder, Ph.D. NMR; protein folding mechanism; protein structure, dynamics and function
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