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The primary
focus of my research is the investigation of neuronal activity through
the combined use of functional magnetic resonance imaging (fMRI) and near-infrared
spectroscopy (NIRS). These two modalities provide complimentary spatial
and temporal measurement of brain blood oxygenation changes during neuro-cognitive
activity. The lab is focused on primary technique and analysis development,
including the design of new infrared probes and MR pulse sequences. This
field spans the areas of MR physics, optics, medical imaging , signal
processing, and biostatistics. In addition to basic research, members
of this group have the opportunity to be involved in on-going applied
experiments with collaborative researchers from neuroradiology, psychiatry,
and psychology.
Selected Publications: Clayton, D.B., M.A. Elliott and R.E. Lenkinski (2001) In vivo proton spectroscopy without solvent suppression. Concepts in Magn. Res. 13:260-275. Walter, G.A., K. Vandenborne,
M.A. Elliott and J.S. Leigh (1999) In vivo ATP synthesis rates
in single human muscles during high intensity exercise. J. Physiol.
(London) 519:901-910. Elliott, M.A., G.A. Walter,
A. Swift, K. Vandenborne, J.C. Schotland and J.S. Leigh (1999) Spectral
quantitation by principal component analysis using complex singular value
decomposition. Magn. Res. Med. 41:450-455. Elliott, M.A., E.K. Insko,
R.L. Greenman and J.S. Leigh (1998) Improved resolution and signal-to-noise
ratio in MRI via enhanced signal digitization. J. Magn. Res. 130:300-304. Elliott, M.A., G.A. Walter, H. Gulish, A.S. Sadi, D.D. Lawson, W. Jaffe, E.K. Insko, J.S. Leigh and K. Vandenborne (1997) Volumetric measurement of human calf muscle from magnetic resonance imaging. Magma 5:93-98.
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