Control of
Gene Expression and
Cellular Programming


 

Joseph A. Baur, Ph.D.
Molecular mechanisms of aging and caloric restriction

Shelley L. Berger,  Ph.D.
Role of adaptors in regulation of transcriptional activation in yeast and humans.

Lawrence Brass, M.D., Ph.D.
Molecular basis for intracellular signaling in vascular  biology

Gideon Dreyfuss, Ph.D.
Nuclear transport, hnRNP complexes, RNA-binding proteins, spinal muscular atrophy

Wafik S. El-Deiry, M.D., Ph.D.
Understanding and developing novel therapeutic strategies for cancer

Aaron Gitler, Ph.D.
Neurodegeneration, Parkinson’s, Alzheimer’s, synuclein, yeast, high-throughput, screening, neurofibromatosis, TDP-43, zebrafish

Todd Lamitina, Ph.D.
Cellular osmoregulation, stress-induced gene expression, C. elegans genetics

Mitchell Lewis, D.Phil.
Gene regulation; protein crystallography; Structural basis of recognition

Kristen W. Lynch, Ph.D.
Mechanism and consequences of regulated alternative splicing

Ronen  Marmorstein, Ph.D.
Crystallography; biochemistry; transcription; cell-cycle;  cancer

Hillary C.M. Nelson, Ph.D.
Structural biology; transcription; protein-DNA interactions; heat shock response

Casim A. Sarkar, Ph.D.
Synthetic biology; cell-fate decisions

James Shorter, Ph.D.
Regulation of beneficial or neuropathogenic prions and amyloids by protein-remodeling factors, molecular chaperones, and small molecules

David Speicher, Ph.D.
Cancer proteomics; structure-function of membrane associated proteins: protein chemistry and mass spectrometry

Gregory D. Van Duyne, Ph.D.
Structural biology; protein-protein interactions; x-ray  crystallography.

John H. Wolfe, V.M.D., Ph.D.
Glycoproteins; lysosomal enzymes;  storage diseases; gene transfer into brain.