FACULTY MEMBERS OF THE BMB GRADUATE GROUP

Listed alphabetically:

A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z

Listed by Research Interest:

Control of gene expression and cellular programming
Cell signaling and intracellular trafficking
Chemical and structural biology
Bioenergetics, metabolism, and membranes
Biomedical imaging and supramolecular assemblies

Listed by Department (Primary Appointment):

Biochemistry and Biophysics Radiology
Physiology Pharmacology
Wistar Institute Chemistry
Bioengineering Biology
Pathology and Lab Medicine Medicine
Cell and Developmental Biology Fox Chase Cancer Center
Veterinary Medicine School of Dental Medicine

  

Charles S. Abrams, M.D. Phospholipid signaling pathways in platelets and lymphocytes

Yair Argon, Ph.D. Quality control of protein folding in the cell by molecular chaperones

Paul H. Axelsen, M.D. Biophysical studies of molecular recognition and rational drug design

Tobias Baumgart, Ph.D. Biomembrane function: thermodynamics, dynamics and mechanics

Joel S. Bennett, M.D. Regulation of integrin function

Shelley L. Berger,  Ph.D. Role of adaptors in regulation of transcriptional activation in yeast and humans

Ben E. Black, Ph.D. Chromosome segregation; chromatin structure; epigenetic centromere specification; hydrogen/deuterium exchange

Kathleen Boesze-Battaglia, Ph.D. Tetraspanin protein structure and role in degenerative disease processes

Ari Borthakur, Ph.D. MRI techniques for clinical applications

Lawrence Brass, M.D., Ph.D.  Molecular basis for intracellular signaling in vascular  biology

Christopher Burd, Ph.D. Phosphatidylinositol signaling; Rab GTPase signaling.

Anthony J. Capobianco, Ph.D. Molecular aspects of Notch signaling; cancer

Britton Chance, Ph.D., Sc.D. Optical spectroscopy and imaging; photon migration in tissues; cancer studies

Barry S. Cooperman, Ph.D. Enzyme catalysis, regulation, ribosomes; kinetics; probes; bioorganic chemistry

Fevzi Daldal, Ph.D. Genetics, structure-function, regulation and biogenesis of cytochromes

William F. DeGrado, Ph.D. Peptide and protein design

Scott L. Diamond, Ph.D. Mechanobiology, gene transfer, blood systems biology, drug discovery, protease chemical-boiology

Roberto Dominguez, Ph.D. Actin cytoskeleton, structural biology

Gideon Dreyfuss, Ph.D. Nuclear transport, hnRNP complexes, RNA-binding proteins, spinal muscular atrophy.

Roland L. Dunbrack, Jr. Ph.D. Methods and applications of protein structure prediction

P. Leslie  Dutton, Ph.D. Oxido-reductase engineering; design and chemical synthesis of redox proteins

Wafik S. El-Deiry, M.D., Ph.D. Understanding and developing novel therapeutic strategies for cancer

Mark Elliott, Ph.D. fMRI and diffuse light imaging neuronal activity

S. Walter  Englander, Ph.D. Protein folding; structure, structure change, and dynamics; H-exchange; NMR

Kathryn M. Ferguson, Ph.D. Structural biology, growth factor receptor signaling, molecular mechanisms of protein-protein interactions

Feng Gai, Ph.D., Spectroscopic study of protein folding/misfolding

Yale E. Goldman,  M.D., Ph.D. Motor proteins studied by photochemistry and spectroscopy

Mark Goulian, Ph.D. Two-component signaling, bacterial regulatory circuits

Doron Greenbaum, Ph.D. Protease function, chemical biology, proteomics, biochemistry, cell biology, malaria

Robin M. Hochstrasser, Ph.D. Photochemical and photobiological  dynamics; nonlinear optical spectroscopy

Roland G.  Kallen, M.D., Ph.D. Structure, function, and regulation of expression of ion  channels

Michael Klein, Ph.D. Computer simulation of lipid membranes, membrane proteins and ion channels

Todd Lamitina, Ph.D. Cellular osmoregulation, stress-induced gene expression, C. elegans genetics

Virginia M.-Y. Lee, Ph.D. Pathobiology of Alzheimer's and Parkinson's disease

Mark A.  Lemmon, Ph.D. Biochemistry/biophysics of intermolecular interactions of  growth factor receptor signaling

Paul A. Liebman, M.D. G-protein-receptor-arrestin mechanisms; visual signal transduction

Mitchell Lewis, D.Phil. Gene regulation; protein crystallography; structural basis of recognition

Zhe Lu, M.D., Ph.D. Structure-function relationship of ion channels; molecular mechanisms of protein-protein interactions

Michael S. Marks, Ph.D. Molecular mechanisms of intracellular protein transport and organelle biogenesis

Ronen  Marmorstein, Ph.D. X-ray crystallography, chromatin regulation, tumor suppressors, oncoproteins, kinases, aging, structure-based inhibitor design

Jeanne C. Myers, Ph.D. Structure-function of basement membrane zone collagens; connective tissue diseases

Hillary C.M. Nelson, Ph.D. Structural biology; transcription; protein-DNA interactions; heat shock response

Tomoko Ohnishi, Ph.D. Structure-function studies of respiratory components;  biological EPR spectroscopy

E. Michael Ostap, Ph.D. Biochemistry of contractile proteins, biophysics of cell motility, and characterization of unconventional myosins

Trevor M. Penning, Ph.D. Structure-function of aldo-keto reductases; role in steroid hormone action and chemical carcinogenesis

Ravinder Reddy, Ph.D. Sodium and oxygen-17 MR methods; multiple quantum and polarization transfer MR techniques

Heinrich Roder, Ph.D. NMR; protein folding mechanism; protein structure, dynamics and function

Harvey Rubin, M.D., Ph.D. Pathogenesis of dormancy in mycobacterium tuberculosis; biomolecular computation and enzymology and cell biology of serine proteases and serine protease inhibitors

Brian M. Salzberg, Ph.D. Multiple-site optical recording; excitation-secretion coupling; neural networks

Jeffery G. Saven, Ph.D. Theory, simulation and design of proteins and folding molecules

John C. Schotland, M.D., Ph.D. Physical optics with applications to biomedical imaging

Kim A. Sharp, Ph.D.  Theory of protein and nucleic acid structure and function

James Shorter, Ph.D. Regulation of beneficial or neuropathogenic prions and amyloids by protein-remodeling factors, molecular chaperones, and small molecules

Emmanuel Skordalakes, Ph.D. X-ray crystallography; telomere biology; cancer and aging

David Speicher, Ph.D.  Cancer proteomics; structure-function of membrane associated proteins: protein chemistry and mass spectrometry

Cecilia Tommos, Ph.D.
Protein radicals and electrochemistry; cation-π interactions; protein forced folding

Phong Tran, Ph.D. Cytoskeleton organization and cellular pattern formation

Jane M. Vanderkooi, Ph.D. Fluorescence; infrared; heme proteins

Gregory D. Van Duyne, Ph.D. Structural biology; protein-protein interactions; x-ray crystallography

Sergei A. Vinogradov, Ph.D. Functional macromolecules, optical imaging probes, porphyrin chemistry, dendrimer chemistry, oxygen microscopy and tomography

A. Joshua  Wand, Ph.D., Graduate Group Chair, Protein structure and dynamics; molecular recognition and signal transduction; NMR spectroscopy

Felix W. Wehrli, Ph.D. MRI of biomaterials microstructure, mathematical modeling, image processing

John W. Weisel, Ph.D. Structural studies of molecular/cellular mechanisms in blood clotting and fibrinolysis

David F. Wilson, Ph.D. Integration of metabolism; oxidative phosphorylation; neuroregulation

Bryan A. Wolf,  M.D., Ph.D. Cytokines and cell death of insulin secreting beta cells and islets; diabetes

John H. Wolfe, V.M.D., Ph.D. Glycoproteins; lysosomal enzymes; storage diseases; gene transfer into brain

Takashi Yonetani, Ph.D. Structure, mechanism, and spectroscopy of hemoproteins and heme enzymes

X. Long Zheng, M.D., Ph.D. ADAMTS13 metalloprotease and microvascular thrombosis