Biochemistry and Molecular Biophysics Graduate Group

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BMB 554/CHEM 555 - Macromolecular Crystallography: Methods and Applications

Fall term

Course Co-Directors: Ronen Marmorstein (Biochemistry and Biophysics) and Emmanuel Skordalakes (Wistar Institute)

This is an introductory course on methods and applications of macromolecular structure determination using X-ray crystallography. The course will be broken up into three parts: 1) Principles of X-ray crystallography involving didactic lectures on the technique wth weekly problem sets; 2) Workshops on macromolecular structure determination involving hands-on experience with the technology; 3) Student "journal club" presentations on current high impact publications involving X-ray crystal structure determination.