Biochemistry and Molecular Biophysics Graduate Group

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BMB 567 (CHEM 567) - Bioinorganic Chemistry

Fall, every year

Instructor:

Ivan Dmochowski , Ph.D.(Room 348, N73) 
ivandmo@sas.chem.upenn.edu

Required Text:

Biological Inorganic Chemistry: Structure and Reactivity by Bertini, Gray, Stiefel and Valentine

Additional Material:

Selected articles from the original scientific literature will be assigned throughout the semester and made available on Blackboard.

Material on Reserve:

the required text
Principles of Bioinorganic Chemistry by S. J. Lippard and J. M. Berg
The Biological Chemistry of The Elements by J. J. R. Frausto da Silva and R. J. P. Williams
Fundamentals of Biochemistry, 2nd Edition by D. Voet and J. G. Voet
Inorganic Chemistry, 4th Edition, by J. Huheey

Grading Scheme:

Homework 5%
First Midterm 17%
Second Midterm 20%
Final Exam 30%
Presentation 20%
Class Participation 8%

Office Hours: Fridays, 12:00 noon - 1 p.m., in Room 348 Chemistry

Sample Schedule:

Week
Topic Book Chapter
1
Introduction, Metal Bonding T.II
2
Biogeochemistry/ Intro to Proteins Chapter 2 /Chapter 3 /T.I
3
Metal Ion Transport/Storage Chapter 5 / Chapter 8
4
Metal Storage / Redox Chemistry Chapter 8 / Chapter 10.1
5
Redox Chemistry / Electron Transfer Chapters 10.1-10.2
6
MIDTERM 1/ GFP Nobel Prize / Midterm Review  
7
Fall Break/ ET + Photosynthesis+Respiration Chapters 10.2-10.3
8
Photosynthesis+Respiration / Photosystem II Chapters 10.3-10.4
9
Peroxidases/ O2 Transport/ O2 Activation Chapters 11.3-11.5
10
Metals in Medicine / MIDTERM 2 Chapter 7
11
Presentations/Presentations  
12
Presentations/Presentations  
13
Presentations/Presentations  
14
Presentations/Presentations