Biochemistry and Molecular Biophysics Graduate Group

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BMB 585 (CAMB/GCB 585) Wistar Cancer Biology Course: Signaling Pathways in Cancer

Fall, every year, The Wistar Institute

Course directors:

Emmanuel Skordalakes, Ph.D., Room 321C, The Wistar Institute, skorda@wistar.org
Ashani Weeraratna, Ph.D., Room 452, The Wistar Institute, aweeraratna@wistar.org

Undergraduates require permission from the course directors

The course will cover basic pathways and mechanisms of cancer development and progression as well as current approaches for the identification of therapies for the treatment of cancer. Each session will consist of a one-hour lecture by one of the Wistar investigators listed below followed by one student presentations 40-45 minutes long on a recently published manuscript. The student presentations will be related to the topic presented and selected by the PI lecturing that day. These presentations will be assigned to the students at the beginning of the course and will serve as part of the final grade. This approach is designed to provide studnets with an integrated learning platform combining up-to-date basic mechanistic understanding of cancer pathways with more translational, disease-relevant topics in cancer therapy and molecular drug discovery.

 

Lecture
Topic Lecturer
1
Cancer Metabolism Dario Altieri
2
Chromatin and Cancer Susan Janicki
3
Viral Tumorigenesis Paul Lieberman
4
Telomeres, Telomerase and Cancer Riethman/Skordalakes
5
Wnt Pathways in Cancer Ashani Weeraratna
6
Cancer Vaccines Hildegund Ertl
7
Oncogenic Signaling by the Ras/Raf Pathway Jesse Villanueva
8
Oncogenesis and Tumor Suppressor Genes Maureen Murphy
9
Anti-Cancer Immunotherapies Jose Conejo-Garcia
10
Gene Suppression Signatures in Cancer Louse Showe
11
Small Molecule Inhibition of Oncogenic Kinases

Ronen Marmorstein

12
Transcriptional and Epigenetic Control of the Metastic Phenotype Frank Rauscher
13
The Tumor Microenvironment Ellen Pure
14
FINAL EXAM