Fall, every year, The Wistar Institute
Course directors:
Qihong Huang, Ph.D., Room 351, The Wistar Institute, qhuang@wistar.org
Emmanuel Skordalakes, Ph.D., Room 321C, The Wistar Institute, skorda@wistar.org
Undergraduates require permission from the course directors
The course will cover basic pathways and mechanisms of cancer development and progression as well as current approaches for the identification of therapies for the treatment of cancer. Each session will consist of a one-hour lecture by one of the Wistar investigators listed below followed by one student presentations 40-45 minutes long on a recently published manuscript. The student presentations will be related to the topic presented and selected by the PI lecturing that day. These presentations will be assigned to the students at the beginning of the course and will serve as part of the final grade. This approach is designed to provide studnets with an integrated learning platform combining up-to-date basic mechanistic understanding of cancer pathways with more translational, disease-relevant topics in cancer therapy and molecular drug discovery.
Lecture |
Topic | Lecturer |
1 |
Cancer as a genetic disease | Kaufman |
2 |
Viral tumorigenesis | Liebermann |
3 |
Gene expression signatures in cancer | Showe |
4 |
Wnt pathways in cancer | Weeraratna |
5 |
BRAF signalilng in melanoma | Herlyn |
6 |
Bcl-2 in follicular lymphoma | Altieri |
7 |
Metastasis and invasion | Huang |
8 |
Transcriptional control in epithelial metastasis | Rauscher |
9 |
Cancer genomics | Davuluri |
10 |
Regulatory T cell in cancer | Hui |
11 |
Small non-coding RNAs | Huang |
12 |
Cancer vaccines | Ertl |
13 |
NO CLASS | |
14 |
Cancer metabolism | Altieri |
15 |
Telomeres telomerase and cancer | Skordalakes |
16 |
FINAL EXAM | Skordalakes/Huang |
17 |
The immune system and cancer | Hu |