|
BMB 509 – Macromolecular Biophysics II
Van Duyne/Wand
M/W, 1:30 – 3:00 p.m.
255 Anatomy-Chemistry Bldg.
Prerequisites: BMB 508 or permission of instructor.
This course introduces fundamental concepts in chemical kinetics and their application to problems in biochemistry such as protein folding and enzymology. There is an emphasis on dynamic processes in proteins and the techniques used to characterize them over a wide range of timescales. The latter half of the course focuses on emerging areas in biochemistry and biophysics including membrane biochemistry, single molecule methods and proteomics with an emphasis on mass spectrometry.
BMB 560 – Methods of Scientific Inquiry in Biological Systems
Wilson & Domotor
Tu/Th, 4:00 – 5:30 p.m.
1001 Stellar-Chance Laboratories
Prerequisites: graduate students in biological sciences or permission of instructors.
The foundational, social and methodological aspects of scientific reasoning in biomedical disciplines are discussed, including: 1) theories, laws, causal/functional explanation and experimental methodology in biology and medicine, 2) case studies in selected fields of biomedical sciences with special regards to strategies in concept and hypothesis formation, discovery, gathering evidence and testing and 3) social and moral factors pertinent to the research enterprise.
BMB 571 – Seminar Course – Imaging Technologies in Biomedical Research
Borthakur & Vinogradov
F, 12:00 noon - 2:00 p.m.
1001 Stellar-Chance Laboratories
This course will focus on modern imaging technologies used in biological research and medicine. The technologies covered will include CT, Ultrasound, MRI, PET, SPECT, and Optical Imaging. Our goal is to provide coverage of principles and enable students to make sound judgement about applicability of imaging methods to biological problems that they will encounter in the future. Simply put, our goal will be reached if after the course, students will feel confident navigating through, e.g. a meeting on molecular imaging, generally understanding most of its topics.
BMB 611 – Advanced X-ray Diffraction Methods
Van Duyne
M/W, 3:00 – 4:30 p.m.
255 Anatomy-Chemistry Building
first half (1/2 semester course; 1/2 credit)
Prerequisites: BMB 554/CHEM555 or equivalent, or permission of course director
Advanced topics in macromolecular x-ray diffraction. Crystallization, synchrotron data collection, data processing, anomalous diffraction, phasing methods, density modification methods, refinement. Emphasis is on applications and currently available methodology.
BMB 626 – Mass Spectrometry and Proteomics
Speicher
M/W, 9:00 – 10:30 a.m.
Wistar Institute
second half (1/2 semester course; 1/2 credit)
This course will provide a detailed introduction to proteomics and mass spectrometry. The role of mass spectrometry in both characterizing proteins for traditional protein structure – function studies and identification of proteins in proteome studies will be emphasized. Targeted and global proteomes, quantitative protein profiling and compositional proteomics, and applications of proteome studies will be discussed. Intended for first and second year graduate students and others with an interest in proteomics or mass spectrometry.
BMB 628 – Principles of Scientific Instruments
Liebman
Tu/Th, 10:30 a.m. – 12:00 noon
104 Anatomy-Chemistry Bldg.
first half (1/2 semester course; 1/2 credit)
Proper use of the tools of one’s trade is essential to quality assurance. General confidence in the infallibility of scientific instruments can be the cause of serious misapplication of research effort. This course systematically reviews first principles of instrumental detection, operation, calibration, truth-testing, trouble shooting and data analysis. Approaches to error appraisal and avoidance are developed using common laboratory examples. Anyone who cares is welcome. And we should all care.
Tutorial, Independent Study and Lab Rotation Courses
BMB 598 – Tutorial
Black
Literature studies in a specific research area under supervision of Biochemistry and Molecular Biophysics Graduate Group faculty, concluded by a written summary and a seminar presentation. Course offered fall, spring and summer semesters.
BMB 705 – Prelim Exam Preparation Course
DeGrado
Days and times to be announced
first half (1/2 semester course; 1/2 credit)
This course is designed for second year BMB students to prepare them for the Preliminary Exam, which must be completed in the spring semester of the second year.
BMB 699 – Laboratory Rotation
Ferguson
Supervised mini-projects for graduate students in BMB, seminar presentation required. Course offered fall, spring and summer semesters.
BMB 799 – Independent Study (Year 1 – 2)
BMB 999 – Independent Study (Years 3 – 5)
|
