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BMB 509 – Macromolecular Biophysics II
Van Duyne & Wand
M/W, 1:30 – 3:00 p.m.
255 Anatomy-Chemistry Bldg
Prerequisites: BMB 508 or permission of instructor
This course introduces fundamental concepts in chemical kinetics and their application to problems in biochemistry such as protein folding and enzymology. There is an emphasis on dynamic processes in proteins and the techniques used to characterize them over a wide range of timescales. The latter half of the course focuses on emerging areas in biochemistry and biophysics including membrane biochemistry, single molecule methods and proteomics with an emphasis on mass spectrometry.
BMB 560 – Methods of Scientific Inquiry in Biological Systems
Wilson & Domotor
M/W, 3:30 – 5:00 p.m.
1001 Stellar-Chance Labs
Prerequisites: graduate students in biological sciences or permission of instructors.
The foundational, social and methodological aspects of scientific reasoning in biomedical disciplines are discussed, including: 1) theories, laws, causal/functional explanation and experimental methodology in biology and medicine, 2) case studies in selected fields of biomedical sciences with special regards to strategies in concept and hypothesis formation, discovery, gathering evidence and testing and 3) social and moral factors pertinent to the research enterprise.
BMB 580 (BE 567) - Mathematical Computational Methods for Modeling Biological Systems
Schotland
T/Th, 12- 1:30 p.m.
Prerequisites: graduate standing or permission of instructor
This course will present a comprehensive account of the application of modeling methodology to the investigation of biological systems. The emphasis will be on an organized overview of the tools and techniques rather than the detailed mathematical structures upon which they may rely. The course will draw examples widely from the current literature in an attempt to not only show the topical relevance of the subject matter but also to equip participants with an understanding of the diversity of domains to which the techniques and methodologies apply.
BMB 581 (BE 581) Techniques of Magnetic Resonance Imaging
Wehrli
M/W, 5 – 6:30 p.m.
255 Anatomy-Chemistry
Detailed introduction to the physics and engineering of magnetic resonance imaging as applied to medical diagnosis. Covered are magnetism, spatial encoding principles, Fourier analysis, spin relaxation, imaging pulse sequences and pulse design, contrast mechanisms, chemical shift, flow encoding, diffusion and perfusion and a discussion of the most relevant clinical applications.
BMB 616 - Medical Problems in Modern Biochemistry
Nelson
Tu/Th, 10:30 a.m. – 12:00 noon
255 Anatomy-Chemistry
Prerequisites: undergraduate biochemistry; undergraduates require permission of course director.
This course on metabolic pathways will focus on diseases and other clinical conditions that have biochemical basis. We will try to understand the mechanisms and manifestations of the biochemical defects, ranging from dysregulation of the pathways to the implications of organ specificity of the defects. Clinical case topics will include familiar diseases such as diabetes, gout, and hypercholesterolemia, as well as rarer diseases such as: MCAD and CPT deficiencies (i.e. fatty acid oxidation defects); von Gierke’s and McArdles disease (i.e. glycogen storage diseases); and propionic acidemias (i.e. amino acid degradation diseases).
BMB 650 - Current Biochemical Topics
Black & Shorter
M, 12:00 noon – 1:00 p.m (255 Anatomy-Chemistry)
Th, 12:00 noon – 1:00 p.m. (Austrian Auditorium)
Th, 1:00 – 2:00 p.m., 248 Anat-Chem (JF Library, 248 Anatomy-Chemistry Building)
Participation in the "Dr. George W. Raiziss Biochemical Rounds", a weekly seminar program sponsored by the Department of Biochemistry and Biophysics. Program deals with a wide range of modern biochemical and biophysical topics presented by established investigators selected from our faculty and by leading scientists from other institutions.
Tutorial, Independent Study and Lab Rotation Courses
BMB 598 – Tutorial
Black
Literature studies in a specific research area under supervision of Biochemistry and Molecular Biophysics Graduate Group faculty, concluded by a written summary and a seminar presentation. Course offered fall, spring and summer semesters.
BMB 705 – Prelim Exam Preparation Course
DeGrado & Lemmon
First half of semester (1/2 semester course; 1/2 credit).
This course is designed for second year BMB students to prepare them for the Preliminary Exam, which must be completed in the spring semester of the second year.
BMB 699 – Laboratory Rotation
Shorter
Supervised mini-projects for graduate students in BMB, seminar presentation required. Course offered fall, spring and summer semesters.
BMB 799 – Independent Study (YRS 1- 2)
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