RNA splicing and disease Transcriptional regulation/histone acetylation Cell cycle control/cancer Chromosome structure and segregation  Programming and function of specialized cell types   Mechanisms of transmembrane signaling Nuclear import/export of RNA Membranes and ion channels Intracellular signaling pathways Apoptosis vs cell survival   Structural basis of molecular recognition Protein design and engineering Pathways of protein folding Enzyme reaction mechanisms Computational approaches to molecular biophysics   Radical mechanisms in metalloenzymes Insulin action/diabetes Electron transfer/redox proteins Integration of metabolism Membrane protein structure   Optical imaging in tissues/cancer In vivo Magnetic Resonance Imaging and spectroscopy Structure and function of macromolecular motors Electron microscopy