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Andrew Avarbock (Ph.D., December 2005)
Thesis Advisor: Harvey Rubin
Thesis Topic: Functional regulation of RelMtb: the stringent response protein responsible for initiating dormancy in Mycobacterium tuberculosis
Current Position: Medical student, University of Pennsylvania School of Medicine, Philadelphia, PA
Email: aavarboc@mail.med.upenn.edu
Sabrina Bedard (Ph.D., May 2006)
Thesis Advisor: S. Walter Englander
Thesis Topic: Hydrogen exchange studies of staphylococcal nuclease folding and unfolding
Postdoc: Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA (Ben Black)
Email: bedard@mail.med.upenn.edu
Marcus G. Bell (Ph.D., December
2000)
Thesis Advisor: Yale Goldman
Thesis Topic: Polarized fluorescence depletion reports orientation distribution
and rotational dynamics of muscle cross-bridges
Postdoc: Department of Pathology, Thomas Jefferson University, Philadelphia,
PA (Robert Barsotti)
Current Position: Assistant Professor of Biomedical Sciences, Philadelphia
College of Osteopathic Medicine, Philadelphia, PA
Email: MarcusBe@pcom.edu
Gretchen Bender (Ph.D., May 2008)
Thesis Advisor: William DeGrado
Thesis Topic: De novo design and characterization of a family of metalloporphyrin proteins
Current Position: Senior Analyst, PriceSpective, LLC, Blue Bell, PA
Email: gbender_upenn@msn.com
Matthew Bentley (Ph.D., August 2008)
Thesis Advisor: Dewey McCafferty
Thesis Topic: Molecular recognition and catalysis in Sortase A from Staphylococcus aureus
Postdoc: Department of Protein Engineering, Genentech, Inc., South San Francisco, CA (Andrea Cochran)
Email: matthew.bentley@gmail.com
Mitchell Berger (Ph.D., May 2004)
Thesis Advisor: Mark Lemmon
Thesis Topic: Mechanisms of ErbB receptor oligomerization
Current Position: Student, University of Pennsylvania School of Medicine, Philadelphia, PA
Email: mberger@mail.med.upenn.edu
Kelley Bethoney (Ph.D., August 2008)
Thesis Advisor: Mark Lemmon
Thesis Topic: Analysis of lipid binding domains in the dynamin family of large GPTases
Postdoc: Department of Physiology, University of Pennsylvania, Philadelphia, PA (Roberto Dominguez)
Email: kbethoney@mail.med.upenn.edu
P. Dayanand Borge (Ph.D., December 2003)
Thesis Advisor: Bryan Wolf
Thesis Topic: IRS-1 inhibition of SERCA: a potential molecular interaction mechanism for regulation of insulin secretion and calcium homeostasis in pancreatic β-cells
Postdoc: Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 (Bryan Wolf)
Email: borge@mail.med.upenn.edu
Ari Borthakur (Ph.D., August
2000)
Thesis Advisor: Ravinder Reddy
Thesis Topic: Sodium NMR: a noninvasive probe for proteoglycan macromolecules
Postdoc: Department of Radiology, University of Pennsylvania School of Medicine,
Philadelphia, PA (Ravinder Reddy)
Current Position: Assistant Professor, Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, PA
Email: borthaku@mail.med.upenn.edu
Nabil Chehab
(Ph.D., December 1999)
Thesis Advisor: Thanos Halazonetis
Thesis Topic: Post translational modifications of the tumor suppressor p53:
how p53 is activated in response to DNA damage
Postdoc: Memorial Sloan Kettering Cancer Center, New York, NY (Nikola Pavletich)
Email: nabil@xray2.mskcc.org
Enn-Ling Chen (Ph.D., August
1998)
Thesis Advisor: John S. Leigh
Thesis Topic: Nuclear magnetic relaxation of water protons in protein solution
and tissue: insights into mechanism and application in MRI using low frequency
dispersion
Visiting Research Scientist, Feinberg Cardiovascular Research Institute, Northwestern
University School of Medicine, Chicago, IL
Current Position: Assistant Research Professor, Division of Cardiology, Department
of Medicine, Duke University Medical Center, Durham, NC
Xiaoxi Chen (Ph.D., December 1999)
Thesis Advisor: P. Leslie Dutton
Thesis Topic: Electron transfer in monolayer films of designed heme proteins
Postdoc: Department of Chemistry, Harvard University, Cambridge, MA (George
Whitesides)
Current Position: Phylos, Inc., Watertown, MA
Email: kchen@phylos.com; kxxchen@hotmail.com
Cheryl E. K. Clarkin (Ph.D., August 1999)
Thesis Advisor: Barbara Weber
Thesis Topic: BRCA1 regulation and DNA damage: a biochemical and genetic analysis
Current Position: Completing M.D. at University of Pennsylvania; University
of Pennsylvania School of Medicine, Philadelphia, PA
Email:cclarkin@mail.med.upenn.edu
David B. Clayton (Ph.D., December
2000)
Thesis Advisor: John S. Leigh
Thesis Topic: Multinuclear magnetic resonance techniquees for the study of brain
metabolism in vivo
Postdoc: Department of Radiology, Stanford University School of Medicine, Lucas
Center for MR Imaging and Spectroscopy, Stanford, CA (Dan Spielman)
Email: dclayton@stanford.edu
Adrienne Clements (Ph.D.,
May 2001)
Thesis Advisor: Ronen Marmorstein
Thesis Topic: Biophysical characterization and structural studies of two E1A-interacting
proteins: the pRB tumor suppressor and the PCAF coactivator
Postdoc: Wistar Institute, Philadelphia, PA 19104 (Ronen Marmorstein)
Current Position: Centocor, Inc., Malvern, PA
Email: adrienne.clements.egan@verizon.net
Robert Daber (Ph.D., May 2009)
Thesis Advisor: Mitchell Lewis
Thesis Topic: Rational design of novel transcriptional regulators
Current Position: Postdoctoral Fellow, Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA
(Mitchell Lewis)
Email: daber@mail.med.upenn.edu
Jennifer L. Dashnau (Ph.D., May 2007)
Thesis Advisor: Jane M. Vanderkooi
Thesis Topic: Biological molecules as protectors against cellular damage caused by environmental extremes: the role of protectant-water interactions
Current Position: Project Engineer, Merck, Lansdale, PA (Dicky Abraham)
Email: jennifer.dashnau@gmail.com
Jamaine Saydu C. Davis (Ph.D., August 2007)
Thesis Advisor: Harvey Rubin
Thesis Topic: Characterization of an alternate ribonucleotide reductase small subunit, NRDF1, from Mycobacterium tuberculosis
Postdoc: National Cancer Institute at Frederick, Frederick, MD (Alex Wlodawer)
Email: jamaines@gmail.com
Ivan Dimitrov (Ph.D., May
2000)
Thesis Advisor: John S. Leigh
Thesis Topic: Diffusion, relaxation, and magnetic resonance imaging studies
of noble gases
Postdoc: Department of Chemistry, University of California, Berkeley, CA (Alexander Pines)
Current Postion: Research Associate, Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, PA
Email: dimitrov@mail.med.upenn.edu
Uma Duvvuri (M.D./Ph.D., May 2002)
Thesis Advisor: John S. Leigh
Thesis Topic: Magnetic resonance relaxation studies of osteoarthritis and tumor response to chemotherapy
Current Position: Resident in Otolaryngology, Hospital of the University of Pennsylvania, Philadelphia, PA
Email: uduvvuri@mail.med.upenn.edu
Dawn Eastmond (Ph.D., May 2004)
Thesis Advisor: Stephen Liebhaber
Thesis Topic: Alteration of gene expression by specially designed RNA decoys
Postdoc: Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia PA (Hillary Nelson)
Current Position: Assistant Director, Leadership Education and Development (LEAD) Program at the Wharton School, University of Pennsylvania
Mark Elliott (Ph.D., May 2000)
Thesis Advisor: John S. Leigh
Thesis Topic: Methods for improved quantitative accuracy in magnetic resonance
imaging and spectroscopy
Postdoc: Department of Radiology, University of Pennsylvania School of Medicine,
Philadelphia, PA (John S. Leigh)
Current Position: Assistant Professor of Radiology, University of Pennsylvania
School of Medicine, Philadelphia, PA
Email: mark@mail.mmrrcc.upenn.edu
Douglas Fletcher (Ph.D., May 1998)
Thesis Advisor: John Haselgrove
Thesis Topic: Hadamard encoded imaging and its in vivo applications
Current Postion: Lieutenant, United States Navy and Assistant Professor of Radiology,
Uniformed Services University of the Health Sciences, Bethesda, MD
Email: dfletcher@usuhs.mil
Maria Fernandez-Seara (Ph.D.,
May 2003)
Thesis Advisor: Felix Wehrli
Thesis Topic: Structural and functional implications of bone water and mineral
density studied by NMR
Postdoc: Functional Imaging Laboratory, London, UK (Robert Turner)
Current Position: Assistant Professor, U. Navarra, Navarra, Spain
Email: mfseara@unav.es
Mary Fitzgerald (Ph.D., December 2005)
Thesis Advisor: Ronen Marmorstein
Thesis Topic: Everted half-site recognition by Leu3: structure/function relationships of a Zn2Cys6 binuclear cluster motif
Postdoc: Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA (Ronen Marmorstein)
Current Position: Postdoc, Rutgers University Center For Advanced Biotechnology And Medicine, Busch Campus, Piscataway, NJ
Email: mfitzger@cabm.rutgers.edu
Brenda A. Frankel (Ph.D., August 2005)
Thesis Advisor: Dr. Dewey G. McCafferty
Thesis Title: Inhibition and catalytic mechanism of the Staphylococcus aureus
Postdoc: Albert Einstein College of Medicine (John Blanchard)
Email: bpetrone@aecom.yu.edu
Kendra King Frederick (Ph.D., December 2006)
Thesis Advisor: A. Joshua Wand
Thesis Topic: Protein dynamics and thermodynamics: a view emerging from NMR relaxation studies on the calmodulin system
Postdoc: Whitehead Institute, Cambridge (Susan Lindquist)
Email: kendrakf@wi.mit.edu
Kelly Gallagher (Ph.D., May
2002)
Thesis Advisor: Kim Sharp
Thesis Topic: Electrostatic contributions to heat capacity changes and an analysis of thermal hysteresis protein hydration using the random network model
Postdoc: Department of Biochemistry and Biophysics, University of Pennsylvania
School of Medicine, Philadelphia, PA (Kim Sharp)
Current Positions: Adjunct Lecturer of Physics, SUNY College at Oneonta, Oneonta,
NY & Faculty Reader, GRE Analytical Writing Assessment, Educational Testing
Services, Princeton, NJ
Email: krg90@bc.edu
Tara Leigh Beers Gibson (Ph.D.,
December 1999)
Thesis Advisor: Pinchas Cohen
Thesis Topic: Effects of proteolysis insulin-like growth factor binding protein-3
binding to insulin-like growth factor-I
Postdoc: Department of Pharmacology, University of Texas Southwestern Medical
Center, Dallas, TX (Melanie Cobb)
Email: tgibs1@mednet.swmed.edu
Scott Keven Gibson (Ph.D.,
December 1999)
Thesis Advisor: Paul Liebman
Thesis Topic: Effects of phosphorylation on rhodopsin's active state equilibrium
and its interactions with G protein and arrestin
Postdoc: Department of Pharmacology, University of Texas Southwestern Medical
Center, Dallas, TX (Al Gilman)
Email: Scott.Gibson@UTSouthwestern.edu
Ari Goldberg (Ph.D., December 2004)
Thesis Advisor: John S. Leigh
Thesis Topic: New approaches to higher resolution images in Diffusion Optical Tomography
Current Position: Student, University of Pennsylvania School of Medicine
Email: arig@mail.med.upenn.edu
Patricia E. Gonzales (Ph.D., May 2005)
Thesis Advisor: Marcos E. Milla
Thesis Topic: Inhibition of the tumor necrosis factor-alpha converting exzyme by its pro domain
Current Position: Research Assistant, Pontificia Univeresidad Catolica del Peru, Lima, Peru
Robert Greenman (Ph.D., May 2000)
Thesis Advisor: Robert Lenkinski
Thesis Topic: Spatial mapping of the concentrations of phosphocreatine in the
human myocardium in vivo
Current Position: Staff Physicist, Beth Israel Deaconess Medical Center and
Instructor, Harvard Medical School, Boston, MA (Robert Lenkinski)
Email: rgreenma@caregroup.harvard.edu
Anne Marie Grosset (Ph.D., May 2000)
Thesis Advisor: P. Leslie Dutton
Thesis Topic: An allosterically regulated reversible mechanical molecular switch:
a de novo protein maquette functions as a redox/ironic strength sensor
coupling chemical binding energy or charge interactions to conformational change
Postdoc: Jefferson Medical College, Philadelphia, PA (Manual Covarrubias)
Current Position: Department of Biochemistry and Molecular Biology, Georgetown University School of Medicine, Washington, DC
Email: anne@bc.georgetown.edu
Feng Guo (Ph.D., May 2000)
Thesis Advisor: Gregory Van Duyne
Thesis Topic: Structural studies on the mechanism of Cre-loxP site-specific
recombination
Postdoc: Department of Chemistry and Biochemistry, Howard Hughes Medical Institute,
University of Colorado at Boulder, Boulder, CO (Tom Cech)
Email: Feng.Guo@colorado.edu
Alan S. Haas (Ph.D., August
2000)
Thesis Advisor: P. Leslie Dutton
Thesis Topic: Design and assembly of catalytically acive monolayer films of
cytochrome c and cytochrome c oxidase
Postdoc: Department of Cancer Cell Biology, Harvard School of Public Health,
Boston, MA (Bruce Demple)
Email: ahaas@hsph.harvard.edu
Jennifer Gronlund Haluko (Ph.D., December 2004)
Thesis Advisior: Dewey McCafferty
Thesis Topic:Studies on the mechanism of histone deacetylase enzymes
Present Position: Research Scientist, Colgate-Palmolive Company, Piscataway, NJ (Malcolm Williams)
Email: jennikins@gmail.com
Vladimira Heredia (Ph.D., December 2004)
Thesis Advisor: Trevor Penning
Thesis Topic: Determinants of the rate-limiting events in 3α-hydroxysteroid dehydrogenase (3α-HSD) catalysis
Postdoc: Department of Biochemistry, Pfizer, Inc., San Diego, CA (Shaoxian Sun)
Current Position: Development Scientist, Amylin Pharmaceuticals Inc., San Diego, CA
Email: VladiH@san.rr.com
Linh Hoang (Ph.D., May 2003)
Thesis Advisor: Walter Englander
Thesis Topic: Transient intermediate units in protein folding
Current Position: Continuing clinical rotations at Hospital of the University of Pennsylvania, Philadelphia, PA
Email: lhoang@mail.med.upenn.edu
David Hokanson (Ph.D., December 2007)
Thesis Advisor: E. Michael Ostap
Thesis Topic: Promiscuous Myo1c and its main squeeze PIP2: it's all about the tail
Postdoc: Department of Cell and Molecular Biology, Cornell University, Ithaca, NY (Anthony Bretcher)
Email: David.Hokanson@gmail.com
Seth Hopkins (Ph.D., May 1997)
Thesis Advisor: Yale Goldman
Thesis Topic: Orientation and motion of myosin's regulatory light chain region
in muscle fibers during force generation and filament sliding
Postdoc: Molecular Design Institute, University of California, San Francisco,
CA (Irwin Kuntz)
Current Position: Sepracor Corporation, Marlborough, MA
Email: seth.hopkins@sepracor.com
Elizabeth A. Hopper (Ph.D., May 1999)
Thesis Advisor: Tomoko Ohnishi
Thesis Topic: Membrane location and special properties of cluster N2 in complex
I of E. coli
Postdoc: Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia,
PA (Maureen Murphy)
Current Postdoc: Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia,
PA (Gary Kruh)
Email: EA_Hopper@fccc.du
Shawn Hou (Ph.D., December
2002)
Thesis Advisor: Robert Ricciardi
Thesis Topic: Transcriptional regulation of MHC class I genes in adenovirus transformed cells: COUP-TF and NF-KB. A tale of two transcription factors
Postdoc: University of Pennsylvania (Robert Ricciardi)
Current Position: Postdoctoral Scientist, Johnson & Johnson, Consumer and Personal Products World Wide, Skillman, NJ
Email: shou@cpcus.jnj.com
Steve Huang (MD/Ph.D., December 2001)
Thesis Advisor: P. Leslie Dutton
Thesis Topic: Structure of a molecular maquette scaffold
Current Position: Resident, Hospital of the University of Pennsylvania, Philadelphia,
PA
Email: sthuang@mail.med.upenn.edu
Justin Hulvershorn (Ph.D., December 2004)
Thesis Advisor: John S. Leigh
Thesis Topic: Imaging neural activity: improved localization, quantitation, and temporal resolution using novel fMRI contrasts
Current Position: Student, University of Pennsylvania School of Medicine
Email: hulversh@mail.med.upenn.edu
Masaru Ishii (MD/Ph.D., August
2001)
Thesis Advisor: John S. Leigh
Thesis Topic: Photon diffusion imaging in model and biological systems
Current Position: Resident, Hospital of the University of Pennsylvania, Philadelphia,
PA
Joseph M. Jez (Ph.D., May 1998)
Thesis Advisor: Trevor Penning
Thesis Topic: Steroid recognition and engineering of catalysis in mammalian aldo-keto reductases
Postdoc: Structural Biology Lab, The Salk Institute for Biological Studies, La Jolla, CA (Joseph Noel)
Current Position: Assistant Professor, Department of Biology, Washington University, St. Louis, MO and Assistant Member & Principal Investigator, Donald Danforth Plant Science Center, St. Louis, MO
Email: jjez@danforthcenter.org
Lil Jia (Ph.D., May 2004)
Thesis Advisor: Jonathan Raper
Thesis Topic: Slits are chemorepellents for retinal ganglion cell axons and trunk neural crest cells
Postdoc: NIDDK, NIH, Bethesda, MD (Douglas Forrest)
Kanli Jiang (Ph.D., August 2001)
Thesis Advisor: John Wolfe
Thesis Topic: Genetic engineering of a therapeutic lysosomal enzyme to improve
its delivery into the central nervous system
Current Position: Medical student, University of Pennsylvania School of Medicine,
Philadelphia, PA
Email: jiangkan@mail.med.upenn.edu
Jonathan H. Kaufman (Ph.D.,
December 2000)
Thesis Advisor: John S. Leigh
Thesis Topic: Magnetic resonance studies of cartilage osmotic and mechanical
properties
Postdoc: Department of Radiology, University of Pennsylvania School of Medicine,
Philadelphia, PA (John S. Leigh)
David Keleti (Ph.D., May 2008)
Thesis Advisor: Mark Lemmon
Thesis Topic: Diversity in molecular recognition of phospholipids by PH domains
Current Position: Medical Writer, Ethos Health Communications, Newtown, PA
Email: dkeleti@alumni.upenn.edu
Soo Hwa Kim (Ph.D., December 2006)
Thesis Advisor: Marcos Milla
Thesis Topic: A functional study of the cytoplasmic domain of tumor necrosis factor-α converting enzyme
Current Position: Analyst, Global Prior Art, Inc., Boston, MA
Email: soohwakim@alumni.upenn.edu
Megan King (Ph.D., December 2004)
Thesis Advisor: Mark Lemmon
Thesis Topic: The role of targeting and effector domains in the functions of dynamin-family GTPases
Postdoc: The Rockefeller University, New York, NY (Guenter Blobel)
Email: mking@rockefeller.edu
Daryl E. Klein (Ph.D., May 2008)
Thesis Advisor: Mark Lemmon
Thesis Topic: Biochemical and structural studies of a secreted antagonist of the Epidermal Growth Factor Receptor
Current Position: Clinics, Hospital of the University of Pennsylvania, Philadelphia, PA
Email: dek@mail.med.upenn.edu
Farhad Kosari (Ph.D., May 1999)
Thesis Advisor: Thomas Kleyman
Thesis Topic: Subunit stoichiometry of the epithelial sodium channel
Postdoc: Mayo Clinic, Rochester, MN (George Vasmatzis)
Email: kosari.farhad@mayo.edu
Astrid Kral (Ph.D., May 2000)
Thesis Advisor: Charles Omer
Thesis Topic: Structure-function studies of farnesyl:proteintransferase
Current Position: Senior Research Biochemist, Merck Research Labs, West Point,
PA
Email: astrid_kral@merck.com
Lisa Lai (Ph.D., December
2001)
Thesis Advisor: Sandra Holloway
Thesis Topic: Characterization of CDC16-183: a novel APC mutant which activates
the spindle checkpoint
Current Position: Postdoc, Department of Pathology, University of Washington, Seattle, WA (Peter Ravinovich)
Email: lail@u.washington.edu
Wai Leung Lau (Ph.D., May
2003)
Thesis Advisor: William DeGrado
Thesis Topic: Folding dynamics and membrane fusion mediated by model coiled-coil
peptides
Postdoc: University of Pennsylvania, Department of Biochemistry and Biophysics, Philadelphia, PA (William DeGrado)
Current Postdoc: MIT, Cambridge, MA (K. Dane Wittrup)
Email: wlau@mit.edu
Anthony Lee (Ph.D., May 2003)
Thesis Advisor: Mark Lemmon
Thesis Topic: Study of the dynamin PH domain and its role in receptor-mediated
endocytosis
Postdoc: University of California, Los Angeles, CA (Linda Liau)
Chun-Chi (David) Li (Ph.D., December 2008)
Thesis Advisor: Kathryn Ferguson
Thesis Topic: Pellino proteins contain a non-canonical FHA domain that mediates the interaction with IRAK1
Postdoc: Department of Physiology, University of Pennsylvania School of Medicine, Philadelphia, PA (Zhe Lu)
Email: lincc@mail.med.upenn.edu
Shuchun (Donald) Li (Ph.D.,
December 2001)
Thesis Advisor: John S. Leigh
Thesis Topic: New methods in MRI susceptometry: theory, experiments, application
Postdoc: Research Associate, Department of Physics, University of Pennsylvania,
Philadelphia, PA
Email: li@NSCP01.physics.upenn.edu
Lin Li (Ph.D., May 2000)
Thesis Advisor: John S. Leigh
Thesis Topic: Harmonic functions, Laplace fields and their applications with
magnetic resonance phase imaging
Postdoc: Department of Radiology, University of Pennsylvania School of Medicine,
Philadelphia, PA (John S. Leigh)
Email: lin@mail.mmrrcc.upenn.edu
Wei Li (Ph.D., August 2002)
Thesis Advisor: Rebecca Taub
Thesis Topic: The role of interleukin-6 and STAT3 in liver regeneration
Postdoc: Genomics Institute of the Novartis Research Foundation (GNF), San Diego, CA (Claudio Joazeiro)
Wenkai Li (Ph.D., December 2007)
Thesis Advisor: Virginia Lee
Thesis Topic: Structural and pharmacological studies on the abnormal aggregation and normal function of tau
Current Position: Senior Research Biologist, Neuroscience Drug Discovery, Merck Research Lab, Boston, MA (Mansuo Hayashi)
Email: wenkaili@mail.med.upenn.edu
Kai Lin (Ph.D., August 1999)
Thesis Advisor: Robert Ricciardi
Thesis Topic: Cloning and functional characterization of DNA polymerases and
processivity factors of human herpes-virus 6 and Kaposi's sarcoma-associated
herpesvirus
Postdoc: Department of Microbiology, University of Pennsylvania School of Dental
Medicine, Philadelphia, PA (Robert Ricciardi)
Current: Investigator, Vertex Pharmaceuticals, Inc., Cambridge, MA
Email: kai_lin@vpharm.com
Xinmin Li (Ph.D., August 2001)
Thesis Advisor: Ronen Marmorstein
Thesis Topic: Biophysical and structural characterizations of the BTB/POZ domain
from the promyelocytic leukemia zinc finger (PLZF)
Postdoc: Los Alamos National Laboratory, Los Alamos, (Paul Langan)
Chia-Shang Jason Liu (M.D./Ph.D., August 2005)
Thesis Advisor: Dr. Mark Elliott
Thesis Title: The nature of the blood oxygen level dependent signal in functioning magnetic resonance imaging: influences and intrinsic functional information
Current Position: Medical student, University of Pennsylvania School of Medicine, Philadelphia, PA
Email: cliu@mail.med.upenn.edu
Lin Liu (Ph.D., May 1999)
Thesis Advisor: Shelley Berger
Thesis Topic: In vitro and in vivo characterization of coactivator
acetyltransferases in transcription regulation
Postdoc: Section of Immunobiology, Yale University School of Medicine, New Haven,
CT (Charlie Janeway)
Email: lin.liu@yale.edu
Zhiqiang Liu (Ph.D., August
1997)
Thesis Advisor: Truman Brown
Thesis Topic: A new Baylesian approach to process chemical shift imaging data
Current: Consultant, CB Technologies, Inc, Malvern, PA
Yingli Ma (Ph.D., August 2005)
Thesis Advisor: Dr. Gregory D. Van Duyne
Thesis Title: Structural and biochemical studies of the Gemin6/7 heterodimer from the human SMN complex
Postdoc: The Howard Hughes Medical Institute, The Rockefeller University, New York, NY (Gunter Blobel)
Email: yingli.ma@gmail.com
Omar Manuar (Ph.D., December
2002)
Thesis Advisor: Dwight Jaggard
Thesis Topic: The effect of parametric direction on scattering from wire loops
Postdoc: University of Pennsylvania, Department of Bioengineering, Philadelphia, PA (Dwight Jaggard)
Email: omar@mail.med.upenn.edu
Eric Mellon (M.D./Ph.D., December 2008)
Thesis Advisor: Ravinder Reddy
Thesis Topic: The regional cerebral metabolic rate of oxygen consumption with proton detected 17O (NOTE: "17" is a superscript) magnetic resonance imaging
during precision 17O2 (O2 - 2 is a subscript) inhalation in swine
Current Position: Not available
Email: emellon@mail.med.upenn.edu
Mohita Jasmine Mohan (Ph.D., August 2005)
Thesis Advisor: Dr. Marcos Milla
Thesis Title: Substrate specificity is a determinant of ectodomain shedding by Tumor Necrosis Factor Alpha Converting Enzyme (TACE)
Current Position: Associate Consultant, L.E.K. Consulting
Email: mohitamohan@yahoo.com
Stephen E. Mulholland (Ph.D.,
December 1997)
Thesis Advisor: P. Leslie Dutton
Thesis Topic: Natural design, chemical synthesis and molecular guidelines for
the assembly of iron-sulfur protein maquettes
Postdoc: Wellman Labs, Massachusetts General Hospital, Boston, MA (Apostolos
Doukas)
Current Position: Research Scientist, Department of Chemistry and Biochemistry,
Biacore, AB, Cambridge, MA
Email: semulholland@earthlink.net
Jianping (Jenny) Ni (Ph.D.,
December 2001)
Thesis Advisor: Gregory Van Duyne
Thesis Topic: Structural studies of arginine repressor from Bacillus stearothermophilus
Postdoc: Department of Biochemistry and Biophysics, University of Pennsylvania
School of Medicine, Philadelphia, PA (Mitchell Lewis)
Email: ni2@mail.med.upenn.edu
Nathaniel Nucci (Ph.D., May 2008)
Thesis Advisor: Jane Vanderkooi
Thesis Topic: On the nature of aqueous solvation in biological systems
Postdoc: Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA (Josh Wand)
Email: nvnucci@mail.med.upenn.edu
Benjamin Howard North (Ph.D., December 2006)
Thesis Advisor: William F. DeGrado
Thesis Topic: Application of the Crick parmeterization to de novo protein design
Postdoc: Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA (Roland Dunbrack, Jr.)
Email: bnorth@mail.med.upenn.edu
Doris Ohliger (Ph.D., August 2001)
Thesis Advisor: Robert Forster
Thesis Topic: Carbonic anhydrase: how does this zinc enzyme work? Carbon-13
magnetization transfer studies of carbon dioxide-bicarbonate exchange
Current Position: HP Technician, Safety Office, University of Pennsylvania School
of Medicine, Philadelphia, PA
Email: doris@ehrs.upenn.edu
Karyn T. O'Neil (Ph.D., December
1998)
Thesis Advisor: William DeGrado
Thesis Topic: Protein engineering by phage display
Past Position: Senior Research Scientist, DuPont Pharmaceutical Company, Wilmington, DE
Current Position: Director, Centocor, Inc., Malvern, PA
Email: koneil@cntus.jnj.com
Nisha Palackal (Ph.D.,
May 2002)
Thesis Advisor: Trevor Penning
Thesis Topic: Role of human aldo-keto reductases in PAH activation
Past Position: Associate Staff Scientist, Diversa Corporation, San Diego, CA
Current Position: Research Scientist, Cayman Chemical Co., Ann Arbor, MI
Email: npalackal@cayman.com
Heather Pinkett (Ph.D., December 2004)
Thesis Advisor: Mitchell Lewis
Thesis Topic: Structural determination of the phage 186 repressor protein
Postdoc: California Institute of Technology, Pasadena, CA (Douglas Rees)
Email: hpinkett@yahoo.com
G. Scott Pesiridis (Ph.D., May 2006)
Thesis Advisor: Gregory Van Duyne
Thesis Topic: Allosteric regulation of PRMT5 by cooperative interactions of the plCln-SmD3 complex
Postdoc: Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA (Gregory Van Duyne)
Email: pesiridi@mail.med.upenn.edu
Naoyuki G. Saito (M.D., Ph.D., December 1998)
Thesis Advisor: Yvonne Paterson
Thesis Topic: Exploring the structural elements of MHC-peptide-TCR interaction
with analogs of VSV-8, an antigenic peptide derived from vesicular stomatitis
virus
Current Position: Assistant Professor, Departments of Radiation Medicine and Pharmacology & Therapeutics, Roswell Park Cancer Institute and Assistant Professor, SUNY, Buffalo
Email: nsaito@med.umich.edu
Vijay Sankaran (M.S.,
May 2002)
Thesis Advisor: Mark Lemmon
Thesis Topic: Examining the differential modes of binding by PI 3-kins product
targets
Current Position: entering MD/PhD program at Harvard University
Email: vijays@sas.upenn.edu
J. Michael Sauder (Ph.D., May 1998)
Thesis Advisor: Heinrich Roder
Thesis Topic: Characterization of intermediates in protein folding
Postdoc: Institute for Cancer Research, Philadelphia, PA (Heinrich Roder)
Postdoc: Institute for Cancer Research, Philadelphia, PA (Roland Dunbrack)
Current position: Scientist, Structural GenomiX, San Diego, CA
Email: msauder@stromix.com
Lumelle Schneeweis (Ph.D., May 2007)
Thesis Advisor: Paul Axelsen
Thesis Topic: Structural and functional analysis of osteoprotegerin and apolipoprotein E
Current Position: Research Investigator, Bristol-Myers Squibb, Princeton, NJ
Email: lumelle.schneeweis@bms.com
Daniel Scolnick (Ph.D., May
2000)
Thesis Advisor: Thanos Halazonetis
Thesis Topic: Cell cycle checkpoints: analysis of CHFR and p53
Postdoc: Department of Genetics, University of Pennsylvania School of Medicine,
Philadelphia, PA (Mark Fortini)
Email: scolnick@mail.med.upenn.edu
Sean-Patrick Scott (Ph.D., August 1998)
Thesis Advisor: Jacqueline Tanaka
Thesis Topic: Predicting and testing the structural basis of nucleotide discrimination
in cyclic nucleotide activated channels
Postdoc: Thomas Jefferson University, Philadelphia, PA (Irene Weber)
Current Position: Research Assistant Professor, Department of Biotechnology,
Temple University, Philadelphia, PA
Email: sscott04@temple.edu
Scott Shandler (Ph.D., May 2009)
Thesis Advisor: William DeGrado
Thesis Topic: Rational design and characterization of beta-peptides, a non-natural peptidomimetic scaffold
Current Position: Postdoctoral Fellow, Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA
(William DeGrado)
Email: shandles@mail.med.upenn.edu
Julia Shifman (Ph.D., December
1998)
Thesis Advisor: P. Leslie Dutton
Thesis Topic: Heme-heme and heme-protein interactions inside de novo
designed four-helix bundle proteins
Postdoc: Howard Hughes Medical Institute Research Labs, California Institute
of Technology, Pasadena, CA (Stephen L. Mayo)
Current Position: Principal Investigator, The Alexander Siberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel
Email: jshifman@cc.huji.ac.il
Liat Shimoni (Ph.D., December 1998)
Thesis Advisor: Jenny Glusker
Thesis Topic: Molecular recognition in selected biological systems
Postdoc: Institute for Cancer Research, Philadelphia, PA (Jenny Glusker)
Current Position: Programmer Analyst, Department of Population Science,
Fox Chase Cancer Center, Cheltenham, PA
Email: Liat_shimoni@hotmail.com
Mark D. Shtilerman (Ph.D., August 1999)
Thesis Advisor: S. Walter Englander
Thesis Topic: Proteins on the edge of extreme (from chaperonin-assisted to ultrafast
protein folding and origins of protein hyperthermostability)
Postdoc: Center for Neurological Diseases, Harvard Medical School, Boston, MA
(Peter Lansbury)
Current Position: Scientific Advisor, Intellectual Property Legal, Igen
International, Inc.
Email: mshtilerman@igen.com
Carol Shultz (Ph.D., May 2009)
Thesis Advisor: Paul Axelsen
Thesis Topic: Quinone reduction by aldo-keto reductases in polycyclic aromatic hydrocarbon activation
Current Position: Process Scientist, Merck & Co., Inc., West Point, PA (Dicky Abraham)
Email: carol.shultz@merck.com
Rachel S. Signarvic (Ph.D., December 2006)
Thesis Advisor: Dr. William F. DeGrado
Thesis Topic: The de novo design of molecular switches: manipulation of secondary structure to modulate conformational stability
Postdoc: Department of Medicine, University Pennsylvania, Philadelphia, PA 19104 (Skip Brass)
Email: signarvi@mail.med.upenn.edu
Avram Slovic (Ph.D., December 2004)
Thesis Advisor: William DeGrado
Thesis Topic: Water-solubilization of integral membrane proteins
Postdoc: Columbia University, New York, NY (James Rothman)
Current Position: Biofuels Program Manager, Amyris Biotechnologies, Brasil
Email: slovic@amyris.com
Joanna Slusky (Ph.D., December 2007)
Thesis Advisor: William DeGrado
Thesis Topic: Sketching nature's energy function: designing helices that target TM proteins and creating software for further design
Postdoc: Department of Biochemistry and Physics, Stockholm University, Stockholm, Sweden (Gunnar von Heijne)
Email: joannas@gmail.com
Young-Han Song (Ph.D., May
1998)
Thesis Advisor: Nancy Cooke
Thesis Topic: Vitamin D binding protein gene: transcriptional regulation and
linkage analysis
Postdoc: Massachusetts General Hospital Cancer Center, Charlestown, MA (Daniel Haber)
Current Position: Associate Professor, Ilsong Institute of Life Science, Hallym University, Gangwon-do, Korea
Email: ysong@hallym.ac.kr
Jeffrey S. Souris (Ph.D., December 1999)
Thesis Advisor: John S. Leigh
Thesis Topic: Diffusing wave emission tomography in highly-scattering systems
Postdoc: Department of Radiology, University of Pennsylvania School of Medicine,
Philadelphia, PA (John S. Leigh)
Email: sourisj@mail.med.upenn.edu
Steven E. Stayrook (Ph.D., May 2001)
Thesis Advisor: Mitchell Lewis
Thesis Topic: Crystal structure of human sterol carrier protein 2
Present Position: Research Assistant, Howard Hughes Medical Institute, University
of Pennsylvania School of Medicine, Philadelphia, PA
Email: stayrook@mail.med.upenn.edu
Alan D. Stein (M.D., Ph.D., August 1998)
Thesis Advisor: John S. Leigh
Thesis Topic: Magnetic resonance elastography: technique development and application
Current: Resident, Hospital of the University of Pennsylvania, Philadelphia,
PA
Email: alan@medcosm.com
Christopher M. Summa
(Ph.D., May 2002)
Thesis Advisor: William DeGrado
Thesis Topic: Computational methods and their applications for de novo
functional protein design and membrane protein solubilization
Postdoc: Department of Structural Biology, Stanford University School of Medicine, Stanford, CA (Michael Levitt)
Current: Assistant Professor, University of New Orleans and Research Institute for Children, New Orleans
Email: csumma@cs.uno.edu
Lawrence Szewczuk (Ph.D., December 2004)
Thesis Advisor: Trevor Penning
Thesis Topic: Selective mechanism-based inactivation of COX-1 by m-hydroquinones
Postdoc: Johns Hopkins University, Baltimore, MD (Philip Cole)
Email: suzak_44@yahoo.com
Change Tan (Ph.D., August
2000)
Thesis Advisor: Peter S. Klein
Thesis Topic: Function and mechanism of frizzled signaling
Postdoc: Department of Genetics, Harvard Medical School, Boston, MA (Norbert
Perrimon)
Current Position: Assistant Professor, Department of Life Sciences, University of Missouri-Columbia, Columbia, MO
Email: tanc@missouri.edu
Mark Tang (Ph.D., August 1997)
Thesis Advisor: Trevor Penning
Thesis Topic: A reassessment of the catalytic mechanism of prostaglandin H2
synthase
Postdoc: California Institute of Technology, Pasadena, CA (Francis Arnold)
Current Position: Alpha Therapeutic, Los Angeles, CA
Email: mswtang@yahoo.com
Zhenyu Tang (Ph.D., May 2000)
Thesis Advisor: Thomas Kadesch
Thesis Topic: Mechanisms of mammalian Notch signaling
Postdoc: Dana-Farber Institute, Harvard Medical School, Boston, MA (Yoshihiro
Nakatani)
Email: Zhenyu_Tang@dfci.harvard.edu
Jeffrey S. Taylor (Ph.D., December 1998)
Thesis Advisor: Roger Burnett
Thesis Topic: Computational biology: methods in automated molecular docking
with applications in structural virology and
antibody-antigen recognition
Postdoc: Duke University, Durham, NC (Lorena Beese)
Email: JTaylor@biochem.duke.edu
Robert M. Tjin Tham Sjin (Ph.D., August 1998)
Thesis Advisors: Barbara Hoffman and Dan Liebermann
Thesis Topic: A novel IL-6 response element confers specificity for JunB induction
in M1 myeloid versus HepG2 hepatoma cells
Postdoc: Temple University School of Medicine, Fels Institute, Philadelphia,
PA (Barbara Hoffman and Dan Lieberman)
Email: r_tjin@hotmail.com
Raymond C. Trievel (Ph.D.,
December 2000)
Thesis Advisor: Ronen Marmorstein
Thesis Topic: Crystal structure, catalytic mechanism, and substrate specificity of the GCN5 histone acetyltransferase family
Postdoc: National Institutes of Health, Bethesda, MD (James Hurley)
Email: trievel@helix.nih.gov
Francesco Vanzi (Ph.D., December
2002)
Thesis Advisor: Yale E. Goldman
Thesis Topic: Mechanical studies of single ribosome/mRNA complexes
Current Position: Research Scientist, European Laboratory for Non-Linear Spectroscopy,
University of Florence, Italy
Email: fvanzi@lens.unifi.it
Ravi Venkataramani (Ph.D.,
May 2001)
Thesis Advisor: Ronen Marmorstein
Thesis Topic: Crystal structure and mutational analysis of cell cycle regulator,
p18INK4c
Postdoc: Wistar Institute, Philadelphia, PA (Ronen Marmorstein)
Current Position: Associate, Booz Allen and Hamilton
Scott T. R. Walsh (Ph.D., August 2000)
Thesis Advisor: William DeGrado
Thesis Topic: Evolution of a de novo designed three-helix bundle protein:
from structure to function and everything in between…
Postdoc: Department of Biochemistry and Molecular Biology, University of Chicago,
Chicago, IL (Tony Kossiakoff)
Current Position: Assistant Professor, Department of Molecular and Cellular Biochemistry, The Ohio State University College of Medicine, Columbus OH
Email: walsh220@osu.edu
Glenn Walter (Ph.D., May 1997)
Thesis Advisor: John S. Leigh
Thesis Topic: Noninvasive evaluation of metabolic capacities in human skeletal
muscles
Postdoc: Department of Physiology, University of Pennsylvania School of Medicine,
Philadelphia, PA (H. Lee Sweeney)
Current Position: Assistant Professor of Physiology and Functional Genomics,
University of Florida, Gainesville, FL
Email: glennw@phys.med.ufl.edu
http://www.med.ufl.edu/phys/glennw.shtml
Jason Wan (Ph.D., May 2005)
Thesis Advisor: Joseph T. Jarrett
Thesis Topic: Flavodoxin-dependent biotin synthase
Postdoc: NIDDK, National Institutes of Health (Jeremy Berg)
Email: jasonwan@mail.nih.gov
Lian Wang (Ph.D., August 1997)
Thesis Advisor: Shelley Berger
Thesis Topic: The function of histone acetyltransferase GCN5 in transcription
regulation
Postdoc: Harvard Medical School, Brigham Women's Hospital, Boston, MA (Elliott
Kieff)
Current Position: Senior Scientist, Department of Biology, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT
Email: lwang@rdg.boehringer-ingelheim.com
Xun Wang (Ph.D., May
2003)
Thesis Advisor: Mortimer Poncz
Thesis Topic: Control of megakaryocyte-specific gene expression by GATA-1 and
FOG-1: role of Ets transcription factors
Postdoc: University of Pennsylvania Department of Pediatrics, Philadelphia, PA (Mortimer Poncz)
Email: xun@mail.med.upenn.edu
Walter Witschey (Ph.D., May 2009)
Thesis Advisor: Ravinder Reddy
Thesis Topic: Rotating frame magnetic resonance imaging techniques
Current Position: Postdoc, University of Freiburg, Freiburg, Germany (Juergen Hennig)
Email: wwitschey@gmail.com
Alissa B. Woska (Ph.D., December
1998)
Thesis Advisor: Michael L. Klein
Thesis Topic: Using computer simulation techniques to determine the structure
and properties of a synthetic 4-helix bundle
Current Position: Research Chemist, Hercules, Inc., Wilmington, DE
Joy (Qingyi) Yang (Ph.D., August 2008)
Thesis Advisor: Kim Sharp
Thesis Topic: New computational tools for macromolecular simulation and modeling: charge assignment, structure modeling, and molecular dynamic simulation
Postdoc: Not available
Email: qyang@mail.med.upenn.edu
Jie Yao (Ph.D., December 1999)
Thesis Advisor: Daniel Kessler
Thesis Topic: Regulation of Xenopus development by the organizer specific gene goosecoid
Email: jj_yao@yahoo.com
Jeongsik Yong (Ph.D., August
2002)
Thesis Advisor: Gideon Dreyfuss
Thesis Topic: Diverse functions of RNA-binding proteins in the biogenesis of
ribonucleoprotein particles
Postdoc: Howard Hughes Medical Institute, University of Pennsylvania School
of Medicine, Philadelphia, PA (Gideon Dreyfuss)
Current Position: Research Assistant Professor of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA
Email: jeongsik@mail.med.upenn.edu
Peng Yuan (Ph.D., August 2008)
Thesis Advisor: Gregory Van Duyne
Thesis Topic: Structural land biochemical studies of site-specific recombinases
Postdoc: Laboratory of Molecular Neurobiology and Biophysics, The Rockefeller Institute, New York, NY (Roderick MacKinnon)
Email: yuanxt@gmail.com
Hui Zhang (Ph.D., May 1999)
Thesis Advisor: Roland G. Kallen
Thesis Topic: Muscle-specific transcription of the rat skeletal muscle tetrodotoxin-resistant sodium channel gene (rSkM2)
Past Position: Product Manager, New England Biolabs, Inc., Beverly, MA
Past Position: Senior Research Scientist, Institute for Systems Biology, Seattle, WA
Current Position: Assistant Professor, Department of Pathology, Johns Hopkins University, Baltimore, MD
Email: hzhang32@jhmi.edu
Omar Zgheib (Ph.D., December 2007)
Thesis Advisor: Thanos Halazonetis
Thesis Topic: Mechanism of recruitment of p53-binding protein 1 (53BP1) to DNA double-strand breaks
Postdoc: University of Geneva, Genva, Switzerland (Thanos Halazonetis)
Email: Omar.Zgheib@molbio.unige.ch
Jinsong Zhang (Ph.D., August 1999)
Thesis Advisor: Mitchell Lazar
Thesis Topic: Regulation and dysregulation of nuclear receptor corepressor-mediated
repression
Postdoc: Laboratory of Biochemistry and Molecular Biology, Rockefeller University,
New York, NY (Robert Roeder)
Email: zhangji@mail.rockefeller.edu
