The co-recipients of the 2013 P. Leslie Dutton Award for Outstanding Dissertation by a BMB graduate student are Ni-Ting Chiou (advisor: Kristen Lynch)
and Morgan DeSantis (advisor: Jim Shorter)
Congratulations to Korrie Mack and Michael Woody, recipients of the 2013 Raiziss Awards.
Kevan Salimian (advisor: Ben Black) sucessfully defended his thesis on September 10th. Congratulations, Kevan!
Gideon Dreyfuss has been elected to the Institute of Medicine. Membership in the IOM is considered to be one of the highest honors in biomedicine.
Josh Allen (Ph.D., 2012; advisor Wafik El-Deiry) has recently joined the pharmaceutical company, Oncoceutics, Inc., as Director of Development.
Congratulations to the August 2013 BMB graduates!
Morgan DeSantis, Ph.D. (advisor: Jim Shorter)
Kathryn Blakey DuPont, Ph.D. (advosr: Feng Gai)
Melissa Martinez-Rivera, Ph.D. (advisor: Cecilia Tommos)
Nisha Ninan,Ph.D. (advisor: Greg Van Duyne)
Lee Solomon, Ph.D. (advisor: Les Dutton)
Shelley Berger and Virginia M.-Y. Lee, have been elected to the 2013 class of members of the American Academy of Arts and Sciences. Read about it here.
Congratulations to second year student, Zhenyu Zhao, who was awarded an NSF Graduate Research Fellowship!
Nicole Martinez-Gonzalez (advisor: Kristen Lynch) is the recipient of a National Research Service Award for her project: "Mechanisms of signal-resposive alternative splicing in T-cell activation".
Robert Magin is a recipient of the 2012 Raiziss Award.
Congratulations to the December 2012 BMB graduates:
Emily Bassett, Ph.D. (advisor: Ben Black)
Geronda Montalvo, Ph.D. (advisor: Bill DeGrado)
Fumin Shi, Ph.D. (advisor: Mark Lemmon)
Christopher Skipwith, Ph.D. (advisor: X. Long Zheng)
See photos from the Second Annual BMB Fall Symposium, Friday, November 2, 2012.Congratulations to Jim Shorter, who has been selected as recipient of the 2012 Michael S. Brown New Investigator Research Award, which recognizes emerging faculty investigators engaged in innovative discoveries.
First year student, Ismail Ahmed, was featured in the latest BGS Newsletter. Read about him here.
We are delighted to announce that Kate Ferguson will serve another three-year term as Chair of BMB!
Please welcome the following new BMB faculty!
Bohdana Discher (Research Assistant Professor of Biochemistry & Biophysics)
Ben Garcia (Presidential Associate Professor of Biochemistry & Biophysics)
Jerry Glickson (Research Professor of Radiology)
John I. Murray(Assistant Professor of Genetics)
Kathryn Wellen (Assistant Professor of Cancer Biology)
View pictures from the 2012 B&B/BMB Retreat here.Congratulations to the August 2012 BMB graduates!
Adam Akl (mentor: David Speicher) has been selected for the NIH Computational Genomics Training Grant.
Congratulations to the winners of the B&B/BMB 2012 Retreat Poster Awards:
Josh Wand First Place Award: Chris Nabel (advisor: Rahul Kohli), Nabel, Christopher S., Laura C. Wang and Rahul M. Kohli. The molecular basis for selective deamination of DNA over RNA by AID/APOBEC enzymes is determined by nucleotide sugar pucker and flexibility.
Second Place: Kevan Salimian (advisor: Ben Black), Salimian, Kevan J., Tanya Panchenko, Dan Hasson, Peter E. Warburton and Ben E. Black. Genomic approaches for studying centromeric chromatin.
Third Place: Nataline Meinhardt (advisor: Doron Greenbaum), Meinhardt, Nataline D., Swapnil Kulkarni, Hyunil Jo, Melanie Millholland, William F. DeGrado and Doron C. Greenbaum. Building specific inhibitors and activity-based probes of calpain by mimicking a natural protein alpha-helix interaction.
Honorable Mention: Ed Ballister (advisor: Mike Lampson), Ballister, Edward R., Zachary Feldman, David M. Chenoweth and Michael A. Lampson. Rapamycin revisited: improving inducible dimerization.
Mark Lemmon has been designated George W. Raiziss Professor in Biochemistry and Biophysics.
Congratulations to Gideon Dreyfuss on his election to the National Academy of Sciences.
Congratulations to the May 2012 BMB graduates!
Tammer, Farid, Ph.D. (advisor:Les Dutton)
David Moore, Ph.D. (advisor: Bill DeGrado)
Katie Sarachan, Ph.D. (advisor: Greg Van Duyne)
John Skinner, Ph.D. (advisor: Walter Englander
Mitch Lewis is recipient of a 2012 Christian R. and Mary F. Lindback Award for Distinguished Teaching, which is Penn's highest teaching honor.
Trevor Penning is the inaugural recipient of the endowed Thelma Brown and Henry Charles Molinoff Professor of Pharmacology.
The 2011 Saul Winegrad Award for Outstanding Dissertation has been awarded to Scott Bresler (advisor:: Mark Lemmon). Scott's dissertation topic was, "Regulation and inhibition of the anaplastic lymphoma kinase".
Kevan Salimian, a graduate student in Ben Black's lab, has been awarded the Dr. Roy G Williams Award for "meritorious research in basic medical sciences", which is one of the 2012 Medical Student Research Paper Prizes. The award was based on Kevan's paper on, "Feedback control in sensing chromosome biorientation by the Aurora B kinase", published in Current Biology last year.
Josh Allen has been selected to participate in the 2012 St. Jude National Graduate Student Symposium (NGSS) where he will present his work on "Potent anti-tumor effects of TIC10 require Foxo3a and TRAIL gene upregulation". Josh is completing his Ph.D. with WafikEl-Deiry at Hershey Medical Center.
Mark Lemmon is the 2012 Awardee of the Dorothy Crowfoot Hodgkin Award of the Protein Society. The Award, sponsored by Genentech, is granted in recognition of exceptional contributions in protein science,which profondly influence our understanding of biology.
Josh Wand was appointed Chair of the NIH Macromolecular Structure and Function B Study Section, effective July 1, 2012.
Morgan DeSantis (Ph.D. student with Jim Shorter) has been awarded a Ruth L. Kirschstein National Research Service Award (NRSA) from the National Institute of Neurological Disorders and Stroke (NINDS)
Molly Sheehan (Ph.D. student with Les Dutton) was selected to give a talk at a Gordon Research Conference on Oxygen Radicals, based on which she won a Young Investigator Award.
A 2011 AACR-Bristol-Myers Squibb Scholar-in-Training Award from the AACR (American Association for Cancer Research) has been awarded to Josh Allen (Ph.D. student with Wafik El-Deiry at Hershey Medical Center)
Congratulations to the December 2011 BMB graduates:
Scott Bresler, Ph.D. (advisor: Mark Lemmon)
Jennifer Greene, Ph.D. (advisor: Harry Ischiropoulos)
David Pilkinton, Ph.D. (advisor: Ravi Reddy)
Aaron Gitler was a finalist in the 2011 annual international competition for The Eppendorf & Science Prize for Neurobiology for his essay, "A simple yeast model provides new insight into complicated human neurodegenerative disease"
Aaron Gitler received the Instituto Paulo Gontijo 3rd International Medicine PG Award for the best ALS research by a young investigator. ALS is amyotrophic lateral sclerosis (also known as Lou Gehrig’s disease).
The first annual BMB Fall Symposium was held on September 30, 2011. See Photos
Dr. Ben Black is the recipient of the Michael S. Brown New Investigator Research Award, a 2011 Penn Medicine Award of Excellence.
Dr. Rahul Kohli has received a $500,000 grant from the Rita Allen Foundation, having been selected because of his research's potential for "revolutionary results." Kohli and his lab group integrate chemical biology and enzymology approaches to study the action of DNA modifying enzymes.
Please welcome our 2011 incoming BMB class! See their pictures here.
Congratulations to Renee Martin, who was awarded the Ph.D. in August 2011. Renee carried out her thesis work with Greg Van Duyne.
The following students were appointed to the Structural Biology & Molecular Biophysics Training Grant:Steve Artim (BMB), Ryan Bradley (CHEM), Ben Capraro (CHEM), Rob Culik (BMB), Devin Dersh (BMB), Alec Ricciuti (BMB), Matt Sochor (BMB), and Matt Stetz (BMB).
Mike Soo (BMB) was recently appointed to the Genetics Training Grant.
Charlie Mo and Chris Yarosh (both BMB) were recently appointed to the Cell & Molecular Biology Training Grant.
Congratulations to the winners of the B&B/BMB 2011 Retreat Poster Awards:
Josh Wand First Place Award: Ed Ballister (advisor: Mike Lampson)
Second Place: Tanya Panchenko (CAMB) (advisor: Ben Black)
Third Place: Morgan DeSantis (advisor: Jim Shorter)
Emily Bassett (advisor: Ben Black)
Kathleen Molnar (advisor: Bill DeGrado)
Elizabeth Sweeny (advisor: Jim Shorter)
Katarina Moravcevic is the recipient of the 2010 Dutton Award for Outstanding Publication by a BMB graduate student (Cell 143:966, 2010.)
2011 American Heart Association Predoctoral Fellowships were awarded to:
Steve Artim (advisor: Mark Lemmon)
Yu-San Huoh (advisor: Kate Ferguson)
Jin Park (advisor: Mark Lemmon)
Kevan Salimian (advisor: Ben Black)
Congratulations to Scott Bresler, who was been awarded the Rose Meadow Levinson Memorial Prize for his paper entitled, "Differential inhibitor sensitiviity of anaplastic lymphoma kinase variants found in neuroblastoma". The prize is awarded for meritorious research in the field of cancer or related area. Scott is an M.D./Ph.D. student in Mark Lemmon's lab.
The 2011 BMB recipient of the Saul Winegrad, M.D., Award for Outstanding Dissertation was awarded to Katarina Moravcevic. Katarina's thesis is entitled, “Investigation of phospholipid effector domains” (advisor: Mark Lemmon)
The M.S. in Biochemistry and Molecular Biophysics was awarded to Brian Frederick in 2011.
Dr. Todd Lamitina is the recipient of the in Molecular and Cellular Physiology, which supports summer research at the Mount Desert Island Biological Laboratory (MDIBL) in Maine.
NSF Research Fellowships have been awarded to the following graduate students:
Laura Castellano (Pharmacology); mentor - Jim Shorter
Janine Hall (Chemical & Biomolecular Engineering); mentor - Matt Lazzara
Peter Huwe (BMB); mentor - Ravi Radhakrishnan
Casim Sarkar, Assistant Professor in the Departments of Bioengineering and Chemical and Biomolecular Engineering, has received a NSF CAREER Award for his proposal, "Engineering Biomolecules and Cells for Oral Protein Delivery." The CAREER award is the NSF’s most prestigious award in support of junior faculty who exemplify the role of teacher-scholars through outstanding research, excellent education and the integration of education and research within the context of the mission of their organizations. Read more
Dr. Gideon Dreyfuss has been named a Fellow of the the American Association for the Advancement of Science (AAAS). Fellows of AAAS are selected for their contributions to science and technology and will be recognized at the Fellows Forum on February 19, 2011 during the AAAS Annual Meeting in Washington, D.C.
Dr. Joel Bennett, Professor of Medicine in the Division of Hematology and Oncology, is a recipient of the 2010 Beutler Prize. This is the highest honor that the American Society of Hematology gives out each year. The Beutler Prize is given to a basic scientist and a clinical investigator whose work has fundamentally changed the field of medicine. Dr. Bennett was recognized for his pioneering laboratory research on the integrin receptor, GPIIb-IIIa.
Congratulations to the December 2010 Graduates!
Katarina Moravcevic, Ph.D. (advisor: Mark Lemmon)
Leslie Milk, Ph.D. (advisor: Walter Englander)
Trey Schroder, Ph.D. (advisor: Yale Goldman)
Neo Wu has been chosen as one of the ten University nominees for the HHMI International Student Research Fellowships.
In 2010, we welcomed the followingnew faculty members to BMB:
Lewis A. Chodosh, Professor of Cancer Biology
J. Alan Diehl, Professor of Cancer Biology
Hua-Ying Fan, Assistant Professor of Biochemistry and Biophysics
Ekaterina L. Grishchuk, Assistant Professor of Physiology
Rahul Kohli, Assistant Professor of Medicine and Biochemistry & Biophysics
Matthew Lazzara, Assistant Professor of Chemical and Biomolecular Engineering
Ravi Radhakrishnan, Associate Professor of Bioengineering
Arjun Raj, Assistant Professor of Bioengineering
Trevor Penning, PhD, director of the Center of Excellence in Environmental Toxicology at the University of Pennsylvania School of Medicine, was named to the 2010 class of American Chemical Society (ACS) Fellows, an honor bestowed upon 192 scientists who have demonstrated outstanding accomplishments in chemistry and made important contributions to ACS, the world’s largest scientific society. The 2010 Fellows were recognized in late August during the Society’s national meeting in Boston. Read more about it.
Aaron Gitler is featured in the August 26, 2010 edition of The Philadelphia Inquirer discussing his recent paper in Nature dealing with his work on ALS.
Elizabeth Sweeny and Nick Bessman are both recipients of 2010 individual American Heart Association Predoctoral Fellowships.
Congratulations to the August 2010 BMB Graduates!
Bryan Gibb (advisor: Greg Van Duyne)
Dan Kulp (advisor: Bill DeGrado)
Karl Schmitz (advisor: Kate Ferguson)
Camella Wilson (advisior: Bryan Wolf)
Usha Ramachandran, M.S.
Julie Rogers (advisor: Feng Gai)
Nathan Scott (advisor: Jane Vanderkooi)
Margaret Tammaro, M.S.
The 2010 Dutton Award for Outstanding Graduate Student Publication was awarded to Trey Schroeder for his article in Current Biology entitled “Motor Number Controls Cargo Switching at Actin-Microtubule Intersections In Vitro” (Schroeder III, H.W, Mitchell, C., Shuman, H., Erika L.F. Holzbaur, E.L.F. and Yale E. Goldman, Y.E., Current Biology 20, 687-96, 2010).
Trey, an M.D./Ph.D. student in the laboratories of Yale Goldman and Erika Holzbaur, presented his research at the Dr. George W. Raisiss 27th Annual Retreat
The Dr. George W. Raisiss 27th Annual Retreat Graduate Student Poster Awards:
Josh Wand Award: Leslie Milk (advisor: Mitch Lewis)
Second Place: Carlos Gay-Antaki (advisor: John Wolfe)
Third Place: Kate Smith (advisor: Feng Gai)
Joseph Laasko has been named the winner of the 2010 Saul Winegrad Award for Outstanding Dissertation in Biochemistry & Molecular Biophysics. Congratulations to Joe and his mentor Professor Michael Ostap
Congratulations to the May 2010 BMB graduates!
Sarah Chobot Hokanson (advisor: Les Dutton)
Daniel Kulp (advisor: Bill DeGrado)
Bruce Lichtenstein (advisor: Les Dutton)
Jim Shorter received a Grand Challenges Explorations grant from the Bill and Melinda Gates Foundation for a project titled “Unleashing Protein Disaggregases to Prevent HIV Infection.” The Grand Challenges Explorations is an initiative to help scientists around the world explore bold and largely unproven ways to improve health in developing countries. Jim’s project focuses on new approaches to fight HIV prevention by engineering enzymes that disassemble protein fibrils found in semen and block HIV transmission.
Mike Lampson, Assistant Professor of Biology, has been appointed as a member of the BMB Graduate Group.
Trevor M. Penning, director of the Center of Excellence in Environmental Toxicology at the School of Medicine, will receive The National Postdoctoral Association (NPA) 2010 Distinguished Service Award at the NPA’s 8th Annual Meeting in March. Dr. Penning is recognized in the postdoctoral community as a longtime advocate on behalf of postdoctoral scholars, both on the home and national fronts. He is also professor of pharmacology, biochemistry and biophysics, and ob/gyn. Dr. Penning is internationally recognized for his research on steroid hormone enzymology and mechanisms by which polycyclic aromatic hydrocarbons cause cancer. He oversaw the formation of the postdoctoral office at Penn, one of the first in the country, and served as the director of the office of postdoctoral programs, and associate dean for postdoctoral research training in the School of Medicine from 1997 to 2001, and as director of biomedical postdoctoral programs from 2001 to 2005.
Congratulations to the December 2009 BMB graduates!
Helena Gaweska, Ph.D. (advisor: Dewey McCafferty)
Joseph Kielec, Ph.D. (advisor: Josh Wand)
Alexei Polishchuk, Ph.D. (advisor: Bill DeGrado)
Mark Lemmon won the 2009 Stanley N. Cohen Biomedical Research Award. This award is given to a University of Pennsylvania School of Medicine faculty member for their body of work in the last five years with an emphasis on biomedical research. Mark was recognized for his work in cellular signaling: signaling by receptor tyrosine kinases (RTKs) and the role of inositol phospholipids in cellular control. His groundbreaking contributions to both of these areas have been internationally recognized, most notably for elegantly combining disciplines from structural and computational biology to cell biology and genetics.
Jim Shorter, Assistant Professor of Biochemistry and Biophysics in the School of Medicine, is a recipient of a 2009 Ellison Medical Foundation New Scholar Award in Aging. The award provides support for newly independent investigators, beginning in their first three years after their postdoctoral training. It also provides funding up to $100,000 per year for a four-year period to a maximum of 25 scholars. Dr. Shorter studies how baker’s yeast can be applied to the study of such lethal nerve degeneration disorders as Alzheimer’s disease.
In 2009, we welcomed the following new faculty members into the BMB Graduate Group:
Joseph Baur, Assistant Professor of Physiology
Morris Birnbaum, Professor of Medicine
Theresa Busch, Radiation Oncology
Paul Janmey, Professor Physiology
Kristen Lynch, Associate Professor of Biochemisry and Biophysics
Mark Lemmon, Diego Alvarado, and Daryl Klein coauthored a paper, “ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor” published in the September 10, 2009 edition of Nature.
Congratulations to the BMB August 2009 graduates!
Sung Hee Choi, Ph.D.
John Gledhill, Ph.D.
Kathleen Hummel, M.S.
Joseph Laakso, Ph.D.
Douglas Metcalf, Ph.D.
Congratulations to Walter Englander who has been named the winner of the 2010 Founders Award of the Biophysical Society "for pioneering the development of hydrogen exchange ('HX') techniques for exploring the stability, interactions and dynamics of macromolecules and their folding." He will receive the Award at the 2010 meeting of the Biophysical Society in San Francisco in February 2010.
Many thanks to Josh Wand for his nine years of service as Chair of the Biochemistry and Molecular Biophysics Graduate Group. Kate Ferguson became the new Chair as of July 1, 2009.
Results from the 2009 Retreat:
Dutton Award: Joe Laasko
Josh Wand First Place: Elizabeth Sweeny
Second Place: Karl Schmitz
Third Place: Joe Kielec
Softball Game Results: Faculty 9, Students 8
Shelley Berger has been named the 10th Penn Integrates Knowledge University Professor. Read more.
Michael Klein, Hepburn Professor of Physical Science in the Department of Chemistry, was one of 72 new members elected into the National Academy of Science. Members are recognized for their distinguished and continuing achievements in original research.
Walter Witschey has been named the winner of the 2009 Saul Winegrad Award for Outstanding Dissertation in Biochemistry & Molecular Biophysics. The award will be presented at the May 18 graduation ceremony. Congratulations to Walter and his mentor Professor Ravi Reddy for a superlative effort.
Congratulations to the May 2009 graduates!
Bob Daber, Ph.D. (mentor: Mitch Lewis)
Scott Shandler, Ph.D. (mentor: Bill DeGrado)
Carol Shultz, Ph.D. (mentor: Trevor Penning)
Walter Witschey, Ph.D. (mentor: Ravi Reddy)
On April 19, Britton Chance received an honorary degree from Huazhong University of Science and Technology (HUST). Dr. Chance strongly supports the field of Biomedical Photonics in China and has a center named after him, the BC CBMP, at HUST.
Congratulations to Mitch Lewis, recipient of the 2009 Dean's Award for Excellence in Basic Science Teaching! This award was established in 1987 to recognize teaching excellence and commitment to medical education in the basic sciences.
Congratulations to the December 2008 graduates!
Chun-Chi (David) Lin, Ph.D. (mentor: Kate Ferguson)
Eric Mellon, Ph.D. (mentor: Ravi Reddy)
Four Penn faculty members have joined the Graduate Group: Casim Sarkar, Assistant Professor of Bioengineering; Aaron Gitler, Assistant Professor of Cell and Developmental Biology; John Crocker, Associate Professor of Chemical and Biomolecular Engineering, and Harry Ischiropoulos, Research Professor of Pediatrics
Kathryn Ferguson received the Michael S. Brown New Investigator Research Award. This Penn Medicine Award of Excellence recognizes emerging faculty investigators engaged in innovative discoveries.
On September 29, 2008, Britton Chance received a 2008 Friendship Award presented by the Chinese government. This award is the highest honor China gives in recognition of foreigners who have made outstanding contributions to China’s economic and social progress. This year, fifty foreigners from nineteen different countries accepted this award. At right, Chinese Premier Wen Jiabao thanks Britton Chance in the Great Hall of People.
A Life in Resonance - A Scientific Symposium to Honor the Memory and Scientific Contributions of John S. Leigh, Ph.D., was held on Friday September 12, 2008, Dunlop Auditorium, University of Pennsylvania.
Congratulations to the August 2008 graduates!
Matthew Bentley, Ph.D. (mentor, Dr. Dewey McCafferty)
Kelley Bethoney, Ph.D. (mentor, Dr. Mark Lemmon)
Joy (Qingyi) Yang, Ph.D. (mentor, Dr. Kim Sharp)
Peng Yuan, Ph.D. (mentor, Dr. Greg Van Duyne)
The P. Leslie Dutton Award for Outstanding Graduate Student Publication was announced at the B&B/BMB Retreat. This annual award was established by the Graduate Group in Biochemistry and Molecular Biophysics in honor of Les Dutton's relentless support of graduate education while Chair of the Department of Biochemistry and Biophysics from 1994 - 2008.
Congratulations to the following students who received Graduate Student Poster Awards at the B&B/BMB Retreat on June 19-20:
First place: Bob Daber (Lewis lab)
Second place (tied): Kathleen Molar (Englander/Shorter labs) & Elizabeth Sweeny (Shorter lab)
Third place: Emily Bassett (Black lab)
Zhe Lu was one of 56 biomedical scientists selected to be a Howard Hughes Medical Institute investigator. His lab develops therapeutic strategies to combat certain diseases that currently lack effective treatment and pursues the answers to fundamental biological questions.
Nathaniel Nucci, Ph.D., is a recipient of the 2008 Saul Winegrad Award for Outstanding Dissertation. Nathaniel's thesis work, "On the nature of aqueous solvation in biological systems", was carried out in the laboratory of Dr. Jane Vanderkooi.
Walter Englander was named the 2007 Herbert C. Sober Lecturer of the American Society of Biochemistry and Molecular Biology. Walter was recognized for his outstanding contributions to biochemistry through his development and application of hydrogen exchange methods.
Dr. Robin M. Hochstrasser, Donner Professor of Physical Sciences, has been elected to the Fellows of The Royal Society of Edinburgh (RSE). He was recognized for being a "pioneer in the innovative use of lasers."
Dr. Tobias Baumgart, Assistant Professor of Chemistry, has been named a Alfred P. Sloan Research Fellow for 2008. The Sloan Research Fellowships honor scientists for research at the frontiers of physics, chemistry, computational and evolutionary molecular biology, computer science, economics, mathematics and neuroscience. Read more
On January 17, 2008, Virginia M.-Y. Lee was a recipient of the 2008 Franklin Founder Award, presented each year by Celebration! Benjamin Franklin, Founder. Dr. Lee was honored for her contributions to finding the underlying causes of and developing novel treatments for Alzheimer's disease, Parkinson's disease,and other neurodegenerative disorders. Read more about it.
A 2008 Harold M. Weintraub Graduate Student Award was given to Daryl Klein. This award recognizes outstanding achievement during graduate studies in biological sciences.
William DeGrado received the American Chemical Society's 2008 Ralph F. Hirschmann Award in Peptide Chemistry, sponsored by Merck Research Laboratories. The award recognizes and encourages "outstanding achievements in the chemistry, biochemistry, and biophysics of peptides.
Dr. Yale Goldman was named Fellow of the American Association for the Advancement of Science. Read more
Jim Shorter is the recipient of a 2007 NIH Director’s New Innovator Award for his research in developing biochemical methods to combat diseases caused by nerve degeneration, such as Parkinson’s, Alzheimer's, and Huntington’s Diseases.