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The Molecular Diagnosis and Genotyping Facility provides molecular biology assays to investigators. Molecular assays are critical to many aspects of basic, clinical, and population research, including molecular stratification of patients entering clinical protocols, molecular epidemiological and pharmacogenetic studies, as well as longitudinal follow-up of patients in clinical investigations.
Since molecular technologies and instrumentation are evolving rapidly, the centralization of molecular testing services within this core facilitates utilization of leading-edge molecular analyses by the investigators. Because some assays are used for clinical decisions during clinical trials, tests are meticulously designed and performed with strict attention to the prevention of polymerase chain reaction (PCR) contamination.
The Facility is a fully equipped molecular biology laboratory staffed by experienced individuals in developing and performing molecular biological assays. While the Facility staff performs most of the assays, investigator-performed studies are actively encouraged through the sharing of Facility procedures, individualized training of investigators or their technical staff, and use of core equipment.
The Facility Director and the Technical Director are available to talk with investigators to explore how the services of the facility can enhance or design their specific research projects. We invite investigators to meet with us in the planning stages of their studies, especially before grant submissions, to discuss services that the core can provide, such as budget information and a description of the core for the resources section of the grant, as well as to plan collection and handling of the specimens for the study. The MDGF is happy to custom design assays to fit any investigators needs. To further inquire about the services of the MDGF, contact the Director. Dr. Don A. Baldwin at dbaldwin@mail.med.upenn.edu or the Technical Director, Dr. Kathakali Addya, at addya@mail.med.upenn.edu.
Molecular Diagnosis and Genotyping Facility 57 John Morgan Building University of Pennsylvania 3620 Hamilton Walk Philadelphia, PA 19104-4283 Phone: 215-746-5431 FAX: 215-573-4452