BUP Leadership & Faculty

Glen Gaulton, PhD
Vice Dean and Faculty Director, Center for Global Health; Interim Director, Botswana-UPenn Partnership

BIO: Glen N. Gaulton, PhD is Vice Dean and Director of the Center for Global Health, and Professor of Pathology and Laboratory of Medicine at the University of Pennsylvania Perelman School of Medicine.In this capacity Dr. Gaulton oversees the full scope of global heath activities in the school with a mission to improve health equity worldwide through improved awareness and access to care, discovery and outcomes based research, and comprehensive educational programs grounded in partnership. Prior to this appointment Dr. Gaulton served for 16 years as the lead scientific officer of the Perelman School. In this capacity he supervised all aspects of the School's research and research training enterprise and was responsible for both stimulating new research endeavors and providing the optimal intellectual and administrative support for ongoing research and education programs.

Dr. Gaulton received his PhD in biochemistry and molecular biology from the University of California, Santa Barbara. He conducted postgraduate research in immunology at the School of Public Health and School of Medicine at Harvard University. In 1985 Dr. Gaulton was appointed Assistant Professor of Pathology and Laboratory Medicine, in the School of Medicine at the University of Pennsylvania.  He was subsequently appointed as Associate Professor with tenure and from 1998 as full Professor. Dr. Gaulton was appointed Associate Dean and Director of the Combined Degree and Physician Scholar Programs in 1993, Director of Biomedical Graduate Studies in 1995, Vice Dean for Research and Research Training in 1998, and as Executive Vice Dean and Chief Scientific Officer in 2006.Dr. Gaulton's research interests are in the area viral pathogenesis, early detection of pathogen infection, and outcomes research in global health. Dr. Gaulton has published over 100 manuscripts and texts, and directly supervised the research training of over forty students and fellows. Dr. Gaulton serves on the Executive Advisory Board of five organizations, is an editor and/or reviewer for nine scholarly journals, and has been chair of four NIH study sections. Dr. Gaulton has received numerous awards for teaching and research, including the Dean's Award for Basic Science Teaching, the Berwick Memorial Teaching Award, the Lindback Award, the Harry Weaver Neuroscience Scholar Award from the National Multiple Sclerosis Society, and the Leukemia Society Scholar Award.





Doreen Ramogola-Masire, MD
Country Director

BIO: Born in Botswana, Doreen Ramogola-Masire graduated with honors from the School of Medicine of the University of Nottingham in the United Kingdom. She then continued her training in Obstetrics and Gynecology first in the United Kingdom and then in the Republic of South Africa at the University of Cape Town, where she also pursued subspecialties in Perinatal Medicine and Cervical Cancer Prevention. During her years of training she participated in the development of the "See and Treat" approach for the diagnosis and management of precervical cancer lesions, which ultimately proved to be a very effective approach currently recommended by the WHO for resource-limited settings. Her experience with "See and Treat" has been instrumental for the success of the implementation of this program for diagnosis and treatment of pre-cervical cancer lesions in HIV-infected women in Botswana. Her training in Perinatal Medicine has made her a key participant in issues of HIV infected pregnant women. She co-directed the first PMTCT clinic in the Western Cape, South Africa, and has been involved in developing national HIV guidelines, also serving in the national HIV Specialist Panel in Botswana. Dr. Ramogola-Masire was recently nominated to serve in the technical working group for piloting universal ART for pregnant women in Botswana. She was appointed as the In-Country Director of the Botswana-UPenn Partnership in January 2009, and has worked closely with Dr. Friedman on recruiting outstanding faculty, nurses, staff and auxiliary personnel to the Botswana-UPenn Partnership.







Staff

Chelsea Robble
Manager, Finance and Administration, Penn Center for Global Health

BIO: Chelsea Robble is the Manager of Finance and Administration for the Center of Global Health. Chelsea’s responsibilities include pre and post-award management, including all accounting activities, and financial and business operations of the Center. Through this responsibility Chelsea will manage all funding for Penn activities in Botswana inclusive of BUP; thus ensuring service excellence and, in a linked manner, compliance with University and in-country policies.

Chelsea was previously appointed in the Department of Otorhinolaryngology- Head and Neck Surgery, at the Perelman School of Medicine where she worked closely with Dr. Erle Robertson. Chelsea holds the Bachelor of Arts in Urban Planning from Binghamton University, and a Master’s in Business Administration, concentrating on finance, from Drexel University, Lebow College of Business.
 





Ari Ho-Foster, MSC
Country Operations Director, Gaborone

BIO: Mr. Ho-Foster completed undergraduate studies in biology with honours at McMaster University in Hamilton, Ontario. He holds a Masters of Science in Applied Epidemiology from the Autonomous University of Guerrero, completed concurrently with a two-year CIET/Health Canada internship to develop local public health infrastructure in several provinces of Atlantic Canada. He brings extensive experience in research management from working in Southern Africa since 2002. From 2002-4, he managed a large nationally-representative study of HIV risk and sexual violence in South Africa, capturing data from over 280,000 youth. He served as a reviewer for a systematic review of HIV prevention programs in 2005-6. In 2007-8, Mr. Ho-Foster was an investigator for a ten-country study of HIV and sexual violence knowledge, attitudes and practices, with management-level involvement in all aspects of the study, and particular focus in design, instrument development, data management and analysis. From 2007-9, Mr. Ho-Foster also was a faculty member on a multi-country initiative to build Southern African research capacity to implement randomized trials in HIV prevention research. In recent years, he was an investigator on a cluster-randomized control trial, assessing the impact of several community level prevention interventions on HIV infection rates (biological endpoints) in communities across Botswana, Namibia and Swaziland. He joined the Botswana-UPenn Partnership as an epidemiologist in June 2010 and took over as Country Operations Director in March 2012.





Ryan Littman-Quinn
Director, Mobile Health Informatics Program

BIO: Ryan Littman-Quinn is a mobile health (mHealth) professional with five years of experience working in both the USA healthcare and global health systems.  Since 2010, he founded, managed and expanded the Botswana-UPenn Partnership (BUP) Health Informatics Capacity Building program. With BUP, Ryan has directed capacity building initiatives and played a major role in the creation, implementation, research, and sustainable scale of 14 mHealth initiatives. All projects fulfill needs within the public health care system in Botswana, ranging from remote specialist access, to public health data collection, to mobile learning (mLearning) initiatives with the recently founded University of Botswana School of Medicine.

Ryan also has extensive mHealth consulting experience with the Centers for Disease Control and Prevention (Kenya, Botswana), the Clinton Foundation (Botswana, South Africa), Invest in Knowledge (Malawi), Hospitalito Atitlan (Guatemala), Vignet (USA), and ManGoes Mobile (USA). He is a regular guest lecturer at the University of Botswana, where he speaks to health science students about health informatics and mHealth, and MBA students about New Media Marketing.






Faculty

Tonya Arscott-Mills, MD
Research Director & Lead Pediatric Clinician

BIO: Dr. Tonya Arscott-Mills trained in Biology at Furman University before completing her undergraduate medical degree at Wake Forest University. She later completed post-graduate training in pediatrics at the St. Christopher's Hospital for Children in Philadelphia. She worked as an international fellow at the Cure International Hospital, Kabul, Afghanistan, and also served as a pediatrician to inner-city populations in Philadelphia, prior to joining the Botswana-UPenn Partnership in 2008.

Between 2008 and 2011, Dr. Arscott-Mills supported outreach and capacity building in clinical care to health facilities situated in northern Botswana from BUP's Francistown office. She currently supports both pre-service and in-service training in facilities in and around Gaborone. Dr. Arscott-Mills is an expert in the pediatric clinical care and management of TB-HIV in Botswana, and advises on several national Ministry of Health technical working groups, and holds faculty appointments at the University of Botswana School of Medicine and the University of Pennsylvania, Perelman School of Medicine. Dr. Arscott Mills was appointed Lead Pediatric Clinician for the BUP in 2013.





Surbhi Grover, MD
Assistant Professor, Radiation Oncology, Perelman School of Medicine of the University of Pennsylvania; Lead Physician, Oncology Program, BUP

BIO: Dr. Surbhi Grover is an Assistant Professor of Radiation Oncology at University of Pennsylvania and Adjunct Senior Lecturer at University of Botswana. She is interested in addressing the growing global cancer burden by focusing on public health endeavors and cost-effective clinical initiatives to improve access to care and outcomes of care in developing countries. Before residency, she worked with Professor Jeffrey Sachs at the Earth Institute and the Gates Foundation on advising the Ministry of Health of India on the National Rural Health Mission, a rural health initiative to strengthen basic and preventive healthcare in rural India.

Since 2011, Dr. Grover has been working with the Botswana-UPenn partnership, strengthening the oncology program in Botswana. She moved full-time to Botswana in 2014. In her current role, she is seeing cancer patients at the public hospital, conducting research and teaching. She is leading the implementation of an ongoing U54 NIH-funded study focused on cervical cancer and she is involved with mentoring several junior investigators at the University of Botswana through the mentoring core of U54. She has also completed a NIH-funded pilot prospective study studying impact of HIV on cervical cancer in Botswana and is currently studying HPV associated cancers in Botswana. She has lead the development of the first gynecological cancers and head and neck cancer multi-disciplinary tumor board to streamline patient treatment and follow up care in the country. Through this current grant application, she will further her work in cervical cancer in Botswana. She will leverage the infrastructure built by the U54 parent grant, her previous cervical cancer project, and the multi-disciplinary gynecological clinic to investigate role of HPV viral load in predicting tumor response and recurrence.





Miriam Haverkamp, MD, MPH
Lead Physician, Basic Care HIV Program

BIO: Dr. Haverkamp formerly worked as an infectious diseases specialist with the Division for Global Health in the department of pediatrics at Massachusetts General Hospital (MGH) in Boston and also served as an instructor at Harvard Medical School. At MGH her focus was on improving triaging and diagnostics of children with severe infections in resource-limited countries. Prior to MGH and Harvard, she trained in adult infectious diseases at Tufts Medical Center in Boston. Miriam’s previous work experience includes two years training in hematology-oncology in Germany, training in internal/social medicine at Montefiore Medical Center in the Bronx, New York where she also served as chief resident. After her chief year she was an NIH supported research fellow for HIV, TB, refugee medicine at Brown University based at Sihnanouk Hospital - Center of Hope in Phnom Penh, Cambodia. During this time she conducted research in the reproductive health of HIV positive women in addition to working as a senior clinician, medical training advisor and providing epidemiology training for local staff. She also served as an international consultant for the World Health Organization and the Cambodian MOH on their national guidelines for communicable disease surveillance and response.

Miriam received her MD from the Medizinische Hochschule Hannover, Germany. She is board certified in internal medicine and infectious diseases. In 2010 the Massachusetts Infectious Diseases Society awarded her the Edward H. Kass Award for Clinical Excellence during Fellowship. She also holds an MPH degree in quantitative methods from Harvard School of Public Health. Miriam joined the Botswana-UPenn Partnership in May 2011 and took over has the Lead for the HIV program in November of the same year.





Joseph Jarvis, MBBS, PhD
Adjunct Assistant Professor of Medicine, Perelman School of Medicine of the University of Pennsylvania

BIO: Joe Jarvis was awarded a Wellcome Trust training fellowship in 2007 to investigate novel treatment and prevention strategies for HIV-associated cryptococcal meningitis in South Africa at the University of Cape Town and the US National Institutes of Health Vaccine Research Centre, leading to a PhD (2012). My key achievements during the fellowship included highlighting the cryptococcal meningitis disease burden in southern Africa (Jarvis AIDS. 2009;23(9):1182-1183), development and implementation of cryptococcal antigen screening as a novel prevention strategy (Jarvis CID 2009; 48(7):856-62), development and evaluation of a novel point-of-care diagnostic test for cryptococcosis (Jarvis CID 2011; 53(10):1019-23), defining optimal treatment regimens for cryptococcal meningitis (Jarvis AIDS 2012; 26(9):1105-1113), and describing the host-immune response to cryptococcal infection (Jarvis JID 2013; 207(12):1817-28).

Subsequent to the fellowship, Joe’s research continues to focus on HIV-related opportunistic infections in sub-Saharan Africa. He has published the largest-ever cohort study (over 500 patients) examining factors associated with mortality in cryptococcal meningitis (Jarvis CID 2014;58(5):736-45), and first-authored publications examining the immune phenotype in HIV-associated cryptococcal meningitis patients, and its relationship with mortality and IRIS (Jarvis PLoS Pathogens 2015;11(4):e1004754, and Jarvis CID 2014;59(4):493-500).

Joe joined the Botswana-UPenn Partnership in February 2014, where he has continued his clinical trials work aimed at improving meningitis outcomes in African settings. He also is examining the utility of novel diagnostics to improve outcomes in HIV-associated meningitis patients (funded by two NIH pilot awards; one investigating the utility of cryptococcal antigen screening as a strategy to reduce cryptococcal-related mortality in African ART programmes; the second developing novel point-of-care PCR based diagnostics for meningitis), and has performed a 15-year nationwide retrospective study (The Botswana National Meningitis Survey) determining incidence and aetiology of meningitis in Botswana, and the impact of the HIV-epidemic and ART roll-out.





Chawangwa Modongo, MB-MRCPI
Lead Physician, TB Program

BIO: Chawangwa Modongo, Assistant Professor of Medicine at the University of Pennsylvania, joined the Botswana-UPenn Partnership (BUP) in 2008. A citizen of Botswana, Chawa earned her MBBS degree from the National University of Galway in Ireland. She currently serves as the lead physician and Principal Investigator for the BUP’s PEPFAR-funded Adult TB Program, which is funded through a $5.5 million grant from the U.S. Centers for Disease Control and Prevention that aims to train and expand the local health care workforce in Botswana with the goal to identify and treat TB mono-infected and HIV/TB dual-infected individuals in order to stop the overlapping epidemics of HIV and TB in Botswana. Today, the majority of TB deaths occur in patients co-infected with HIV, many caused by delays and difficulties related to early diagnosis.

Dr. Modongo is one of the most experienced physicians in Botswana in managing HIV/TB co-infected patients as well as multi-drug resistant TB. For the past decade she has managed most of the MDR-TB, complicated TB cases, and TB cases with adverse effects secondary to HIV and/or TB drugs in the country. Through these efforts she has helped develop a national-level cohort of MDR-TB patients. The analyses on this cohort have allowed the description of the treatment outcomes, identification of high ototoxicity rates and pharmacokinetic studies of amikacin in this population. Dr. Modongo has been a co-investigator in several NIH funded TB projects implemented in Botswana in collaboration with Drs. Zetola, Bisson, and Klausner investigating clinical and diagnostic implications of mixed TB infections and bacterial microevolution and pioneering new new TB diagnostics.





Chelsea Morroni, MD, MPH, PhD
Adjunct Assistant Professor of Medicine Family, Perelman School of Medicine of the Univesity of Pennsylvania; Family Planning and Sexual and Reproductive Health Doctor, BUP

BIO: Dr. Chelsea Morroni has extensive experience in strengthening family planning, and sexual and reproductive health service provision more broadly, in resource poor settings. She has lived and worked in this field in southern Africa for nearly 20 years. She currently directs the Botswana Sexual and Reproductive Health Initiative, and is a medical advisor to the Botswana Family Welfare Organisation (the only non-governmental provider of family planning services in Botswana) and is a special advisor to the Botswana Ministry of Health Family Planning Programme.

In addition to having experience of public health programs in developing countries, Dr Morroni also brings with her an extensive academic pedigree. She has a BA in social anthropology from Harvard University, an MPH and medical degree from the University of Cape Town, an MPhil and PhD in epidemiology from Columbia University, a Diploma in Tropical Medicine from the London School of Hygiene and Tropical Medicine and a Diploma in Sexual and Reproductive Healthcare from the UK Faculty of Sexual and Reproductive Healthcare. She is currently appointed in the Institute for Women’s Health and the Institute for Global Health, University College London, with honorary appointments at the University of Cape Town, the University of Botswana, the Botswana Harvard Aids Institute Partnership and the University of Pennsylvania Perelman School of Medicine.





Giacomo Paganotti, PhD
Research Associate, Lab Supervisor

BIO: Dr. Paganotti was born in Rome, Italy. He graduated in zoology at the Department of Biology of the University of Rome “Tor Vergata”, studying the relationship between the bilateral degree of wing asymmetry and the male mating success of two species of damselflies with a field and laboratory approach (both morphometry and genetics). In September 1997, he was awarded a doctoral fellowship from the University of Modena (Italy) to study the genetic variability in Plasmodium falciparum natural populations in Burkina Faso, West Africa, in different ethnic groups with different susceptibilities to malaria. In December 2002, he was awarded an Institute Pasteur – Cenci Bolognetti Foundation fellowship (2002-2004) to study P. falciparum gametocyte production in two different ethnic groups of Burkina Faso. He spent six months in West Africa during 2002 to carry out the survey in the villages and collect mosquitoes and blood samples for this project. In September 2005, he was awarded an Institute Pasteur – Cenci Bolognetti Foundation Return Fellowship to study P. falciparum multiplicity of infection and chloroquine resistance in subjects from Burkina Faso. During the last years, he started to develop the new hypothesis that human genetic variation in drug metabolising enzymes could influence the distribution of parasite drug resistance alleles.

In November 2013 he accepted a research associate position at the Botswana-UPenn Partnership in where he will continue his research and supervise the BUP Core lab at Univ. of Botswana and the BUP lab in the National Health lab in Gaborone. His main research focus will be to look at the possible interaction between ART and HIV drug resistance, both looking at human poor metaboliser and ultra-rapid metaboliser alleles and the associated risk of speeding virus drug resistance selection in Botswana. He is also interested in HHV-8’s modality of mother to child transmission through saliva applied on the child’s skin after the bites of blood feeding arthropods.

Dr. Paganotti has been published in Nature (2001), the American Journal of Tropical Medicine and Hygiene (2004), Parasitology (2006), Malaria Journal (2008, 2012), Journal of Infectious Diseases (2011).





Nicola Zetola, MD, MPH
Research Assistant Professor of Radiation Oncology, Perelman School of Medicine of the University of Pennsylvania






Founding Director

Harvey Friedman, MD
Founding Director

Dr. Friedman served as the Director of the Botswana-UPenn Partnership for 15 years from its beginning in 2001 until 2016 and oversaw the growth of the program from a handful of volunteer physicians to a one involving ten of Penn’s twelve schools, and more than 150 full-time Botswana based faculty and staff, and key partners at the University of Botswana and the Ministry of Health. In his role as Director, he had the pleasure of meeting and working with a number of world leaders in the fight against HIV/AIDS in Botswana including Former Presidents Ketumile Masire and Festus Mogae of Botswana and George W. Bush of the United States. In his time working in Botswana, Dr. Friedman was proud to have witnessed and been part of what is considered to be one of the most ambitious and successful national HIV/AIDS treatment programs ever instituted.

Dr. Friedman continues to serve as PI on some Botswana-based grants.









Chelsea Robble
Manager of Finance and Administration, Penn Center for Global Health

BIO: Chelsea Robble is the Manager of Finance and Administration for the Center of Global Health.  Her responsibilities include pre and post-award management, including all accounting activities, and financial and business operations of the Center.  Through this responsibility Chelsea manages all funding for Penn activities in Botswana inclusive of BUP; thus ensuring service excellence and, in a linked manner, compliance with University and in-country policies.

Chelsea was previously appointed in the Department of Otorhinolaryngology- Head and Neck Surgery, at the Perelman School of Medicine where she worked closely with Dr. Erle Robertson. Chelsea holds the Bachelor of Arts in Urban Planning from Binghamton University, and a Master’s in Business Administration, concentrating on finance, from Drexel University, Lebow College of Business.


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